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# airway_allergic_asthma | ||
Welcome! Here, we present our study of allergic asthma in the human airway. | ||
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## Read the paper :mortar_board: | ||
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Please read and cite our original research article: | ||
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- CITATION | ||
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## Explore the data :microscope: | ||
<table> | ||
<tr> | ||
<td width="33%"> | ||
<a href="https://villani.mgh.harvard.edu/allergy-asthma/app/?ds=AEC_data&gene=MAL&groupby=none"> | ||
<img src="https://user-images.githubusercontent.com/209714/208189301-54950cab-9d7e-46e4-ba95-6f18e0bae550.png"></img> | ||
</a> | ||
</td> | ||
<td> | ||
<b>Cell Clusters</b> | ||
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Metadata variables and gene expression in two-dimensional embeddings. | ||
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3 cell lineages: | ||
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- Epithelial cells, Mononuclear phagocytes, T cellslls | ||
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:point_right: <a href="https://villani.mgh.harvard.edu/allergy-asthma/app/?ds=AEC_data&gene=MAL&groupby=none">View Cell Clusters</a> | ||
</td> | ||
</tr> | ||
<tr> | ||
<td> | ||
<a href="https://villani.mgh.harvard.edu/allergy-asthma/gene-contrasts/"> | ||
<img src="https://user-images.githubusercontent.com/209714/208189495-d2c43409-d81e-4e06-86b8-5567ac79dc36.png"></img> | ||
</a> | ||
</td> | ||
<td> | ||
<b>Gene Contrasts</b> | ||
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Differential expression statistics for all genes across: | ||
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- 2 contrasts (condition Ag vs Bln, group AA vs AC) | ||
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:point_right: <a href="https://villani.mgh.harvard.edu/allergy-asthma/gene-contrasts/">View Gene Contrasts</a> | ||
</td> | ||
</tr> | ||
</table> | ||
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## Read the source code 💻 | ||
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This repository includes two folders: | ||
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[deg_table/][deg_table] | ||
- The differentially expressed gene tables. | ||
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[figure_scripts/][figure_scripts] | ||
- The source code for creating the figures that appear in the manuscript. | ||
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[deg_table]: https://github.com/villani-lab/airway_allergic_asthma/tree/main/deg_table | ||
[figure_scripts]: https://github.com/villani-lab/airway_allergic_asthma/tree/main/figure_scripts | ||
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## Download the data 💾 | ||
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The raw and processed scRNA-seq gene expression files are available at NCBI GEO | ||
[GSE193816]. | ||
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[GSE193816]: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE193816 |