The Polygenic Score Catalog Calculator is a nextflow pipeline for polygenic score calculation
As a part of COVID-19 Host Genetics Initiative, we perform the following set of analyses to better understand the genetic basis of COVID-19 susceptibility and severity.
CoMorMent-Containers
Variational Inference of Polygenic Risk Scores
A toolkit to calculate polygenic scores using PLINK2, PRS-CS, RapidoPGS, or PRSice2.
quincunx: an R package to query, download and wrangle PGS Catalog data
Software program for generating synthetic datasets for genotypes and phenotypes
Toolkit for the efficient construction and analysis of polygenic risk scores in R.
Multi Kernel Linear Mixed Models for Complex Phenotype Prediction
quincunx: an R package to query, download and wrangle PGS Catalog data
Python applications and libraries for working with PGS data and the PGS Catalog
(superseded by pygscatalog) Utilities for working with PGS Catalog API and scoring files
This repository contains the programming codes used in Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types https://advances.sciencemag.org/content/7/3/eabd9036
Polygenic risk modeling with latent trait-related genetic components
power calculator for Genetic Risk Scores (GRS)
Those are the code files for producing the PheWAS analyses in the manuscript "Phenome-Wide Association Study of Polygenic Risk Score for Alzheimer’s Disease in Electronic Health Records". Part of our analyses included sensitive genomic data. Codes to produce AD PRS were not included here.
Machine Learning in Genomics and Healthcare (COMP 565) Project
Machine Learning in Genomics and Healthcare (COMP 565) Project
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