Created on Tue Auguest 24 2021 @author: Quinton Dowling

INTRODUCTION This directory contains scripts and flags for generating pseudo-symmetric trimeric proteins and nanocage desing. Two directories are included:

Pseudosymmetric Design: Contains scripts, input files, and README for enumerating pairwise point mutations in the 3-fold interface Nanocage Design: Contains scripts, input files, and README for desiging nanocage interfaces

REQUIREMENTS Rosetta 3.14 https://docs.rosettacommons.org/docs/latest/Home tcDock Bale, Jacob B., Shane Gonen, Yuxi Liu, William Sheffler, Daniel Ellis, Chantz Thomas, Duilio Cascio, et al. 2016. “Accurate Design of Megadalton-Scale Two-Component Icosahedral Protein Complexes.” Science 353 (6297): 389–94.