diff --git a/src/ontology/fypo-edit.owl b/src/ontology/fypo-edit.owl index 2eac56da..ac083713 100644 --- a/src/ontology/fypo-edit.owl +++ b/src/ontology/fypo-edit.owl @@ -8692,6 +8692,19 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -15383,8 +15396,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PomBase:mah") oboInOwl:hasRel AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PomBase:mah") oboInOwl:hasRelatedSynonym "increased duration of mitotic G1 phase during vegetative growth") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PomBase:mah") oboInOwl:hasRelatedSynonym "increased duration of mitotic G1 phase progression") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PomBase:mah") oboInOwl:hasRelatedSynonym "mitotic cell cycle delay in G1") -AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SGD:phenotype_annotation") oboInOwl:hasRelatedSynonym "mitotic cell cycle progression in G1 phase: delayed") -AnnotationAssertion(Annotation(oboInOwl:hasDbXref "SGD:phenotype_annotation") oboInOwl:hasRelatedSynonym "mitotic cell cycle progression in G1 phase: increased duration") AnnotationAssertion(oboInOwl:id "FYPO:0000333") AnnotationAssertion(rdfs:comment "A G1/S delay may indicate that a checkpoint, such as the cell size checkpoint or the G1/S DNA damage checkpoint, is activated. Checkpoint activation can be tested using checkpoint kinase mutants.") AnnotationAssertion(rdfs:label "mitotic G1/S phase transition delay") @@ -131678,7 +131689,7 @@ AnnotationAssertion(oboInOwl:created_by "2024-05-03T12:03:19Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") AnnotationAssertion(rdfs:label "abolished protein neddylation during vegetative growth"@en) -SubClassOf( ) +SubClassOf( ) # Class: (normal histone H3-K14 acetylation at silent mating-type cassette during vegetative growth) @@ -131762,6 +131773,124 @@ AnnotationAssertion(rdfs:label "in EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) SubClassOf( ) +# Class: (abnormal mitotic S/G2 phase transition) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10947840") "A cellular process phenotype in which a cell does not execute a mitotic S/G2 cell cycle phase transition normally.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:34:01Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "abnormal mitotic S/G2 phase transition"@en) +SubClassOf( ) + +# Class: (increased histone H3-K56 acetylation in transcribed regions during mitotic G2/M phase) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27268234") "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which acetylation of lysine at position 56 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:41:42Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "increased histone H3-K56 acetylation in transcribed regions during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (increased histone H4-K20 monomethylation in transcribed regions during mitotic G2/M phase) + +AnnotationAssertion( "A cellular process phenotype observed in the G2/M phase of the mitotic cycle in which monomethylation of lysine at position 20 of histone H4 in regions of the genome that are actively transcribed occurs to a greater extent than normal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:48:50Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "increased histone H4-K20 monomethylation in transcribed regions during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (normal histone H3-K56 acetylation during mitotic G2/M phase) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27268234") "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which acetylation of lysine at position 56 of histone H3 is normal (i.e. indistinguishable from wild type).") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:51:36Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "normal histone H3-K56 acetylation during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (normal histone H4-K20 monomethylation during mitotic G2/M phase) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27268234") "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which monomethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type).") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:56:48Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "normal histone H4-K20 monomethylation during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (normal histone H4-K20 trimethylation during mitotic G2/M phase) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27268234") "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which trimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type).") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T05:58:53Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "normal histone H4-K20 trimethylation during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (decreased histone H4-K20 trimethylation during mitotic G2/M phase) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:27268234") "A cellular process phenotype observed during the G2/M phase of the mitotic cell cycle in which trimethylation of lysine at position 20 of histone H4 is decreased.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:01:40Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "decreased histone H4-K20 trimethylation during mitotic G2/M phase"@en) +SubClassOf( ) + +# Class: (increased cellular phosphate (Pi) level) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37949217") "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) measured in a cell (total or free) is higher than normal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:11:57Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission _yeast_phenotype") +AnnotationAssertion(rdfs:label "increased cellular phosphate (Pi) level"@en) +SubClassOf( ) + +# Class: (increased total cellular phosphate (Pi) level) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37949217") "A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of phosphate (Pi) measured in a cell is higher than normal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:19:32Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "increased total cellular phosphate (Pi) level"@en) +SubClassOf( ) + +# Class: (increased free cellular phosphate (Pi) level) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37949217") "A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of free phosphate (Pi) measured in a cell is higher than normal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:22:59Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "increased free cellular phosphate (Pi) level"@en) +SubClassOf( ) + +# Class: (abnormal phosphate export) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37949217") "A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of phosphate ions (Pi) out of a cell is abnormal.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:31:25Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "abnormal phosphate export"@en) +SubClassOf( ) + +# Class: (sensitive to phosphate (Pi)) + +AnnotationAssertion( "A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate (Pi). Cells stop growing (and may die) at a concentration of phosphate that allows wild type cells to grow.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:42:53Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "sensitive to phosphate (Pi)"@en) +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) + +# Class: (increased lactate dehydrogenase activity) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37787465") "A molecular function phenotype in which the observed rate of lactate dehydrogenase activity is increased.") +AnnotationAssertion(oboInOwl:created_by "vw") +AnnotationAssertion(oboInOwl:creation_date "2024-05-20T06:54:47Z"^^xsd:dateTime) +AnnotationAssertion(oboInOwl:hasOBONamespace "fission_yeast_phenotype") +AnnotationAssertion(rdfs:label "increased lactate dehydrogenase activity"@en) +SubClassOf( ) + # Class: (decreased rate of cytoplasmic microtubule polymerization during mitotic interphase) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36633091") Annotation(oboInOwl:hasDbXref "PomBase:mlr") "A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a lower rate, or speed, than normal.")