diff --git a/Dockerfile b/Dockerfile
index 3a5fc38..d8cf8a0 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -8,10 +8,6 @@ WORKDIR /opt/app
 RUN set -xe \
     && apt-get update \
     && apt-get install python3-pip -y
-# RUN pip3 install --upgrade pip
-# RUN python3 -m pip install -i https://pypi.tuna.tsinghua.edu.cn/simple --upgrade pip
-# RUN pip config set global.index-url https://pypi.tuna.tsinghua.edu.cn/simple 
-# RUN pip install -r requirements.txt --default-timeout=1000
 COPY . /opt/app
 
 RUN apt-get update
@@ -21,18 +17,13 @@ RUN wget \
     && mkdir /root/.conda \
     && bash Miniconda3-latest-Linux-x86_64.sh -b \
     && rm -f Miniconda3-latest-Linux-x86_64.sh
-RUN conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/pkgs/free/ \
-    && conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/pkgs/main/ \
-    && conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/conda-forge/
+# RUN conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/bioconda/
+# RUN conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/pytorch/
+# RUN conda config --set show_channel_urls yes
 RUN conda install -c bioconda anarci
-RUN conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/pytorch/ \
-    && conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/pkgs/free/ \
-    && conda config --set show_channel_urls yes
-RUN conda config --set remote_read_timeout_secs 1000.0
-# RUN conda install -c bioconda anarci
 RUN conda install pytorch==1.10.0 cudatoolkit=10.2 -c pytorch
 
-RUN pip config set global.index-url https://pypi.tuna.tsinghua.edu.cn/simple
+# RUN pip config set global.index-url https://pypi.tuna.tsinghua.edu.cn/simple
 RUN python -m pip install --upgrade pip
 RUN pip install biopython==1.79
 RUN pip install pytorch-lightning==1.6.4
diff --git a/data/cluster/reslevel_cdr3_cluster_0.2.pkl b/data/cluster/reslevel_cdr3_cluster_0.2.pkl
new file mode 100644
index 0000000..213167c
Binary files /dev/null and b/data/cluster/reslevel_cdr3_cluster_0.2.pkl differ
diff --git a/data/cluster/reslevel_epi_cluster_0.2.pkl b/data/cluster/reslevel_epi_cluster_0.2.pkl
new file mode 100644
index 0000000..f2e353a
Binary files /dev/null and b/data/cluster/reslevel_epi_cluster_0.2.pkl differ
diff --git a/data/cluster/seqlevel_epi_cluster_0.5.pkl b/data/cluster/seqlevel_epi_cluster_0.5.pkl
new file mode 100644
index 0000000..33c2c51
--- /dev/null
+++ b/data/cluster/seqlevel_epi_cluster_0.5.pkl
@@ -0,0 +1,2859 @@
+(dp0
+S'>Epi_59'
+p1
+cnumpy.core.multiarray
+scalar
+p2
+(cnumpy
+dtype
+p3
+(S'i4'
+p4
+I0
+I1
+tp5
+Rp6
+(I3
+S'<'
+p7
+NNNI-1
+I-1
+I0
+tp8
+bS'\x16\x00\x00\x00'
+p9
+tp10
+Rp11
+sS'>Epi_58'
+p12
+g2
+(g6
+S'n\x00\x00\x00'
+p13
+tp14
+Rp15
+sS'>Epi_51'
+p16
+g2
+(g6
+S'\x93\x00\x00\x00'
+p17
+tp18
+Rp19
+sS'>Epi_50'
+p20
+g2
+(g6
+S'\x04\x00\x00\x00'
+p21
+tp22
+Rp23
+sS'>Epi_53'
+p24
+g2
+(g6
+S';\x00\x00\x00'
+p25
+tp26
+Rp27
+sS'>Epi_52'
+p28
+g2
+(g6
+S'v\x00\x00\x00'
+p29
+tp30
+Rp31
+sS'>Epi_55'
+p32
+g2
+(g6
+S'n\x00\x00\x00'
+p33
+tp34
+Rp35
+sS'>Epi_54'
+p36
+g2
+(g6
+S'Z\x00\x00\x00'
+p37
+tp38
+Rp39
+sS'>Epi_57'
+p40
+g2
+(g6
+S'\xcc\x00\x00\x00'
+p41
+tp42
+Rp43
+sS'>Epi_56'
+p44
+g2
+(g6
+S'v\x00\x00\x00'
+p45
+tp46
+Rp47
+sS'>Epi_328'
+p48
+g2
+(g6
+S'n\x00\x00\x00'
+p49
+tp50
+Rp51
+sS'>Epi_329'
+p52
+g2
+(g6
+S'n\x00\x00\x00'
+p53
+tp54
+Rp55
+sS'>Epi_322'
+p56
+g2
+(g6
+S'f\x00\x00\x00'
+p57
+tp58
+Rp59
+sS'>Epi_323'
+p60
+g2
+(g6
+S'r\x00\x00\x00'
+p61
+tp62
+Rp63
+sS'>Epi_320'
+p64
+g2
+(g6
+S'n\x00\x00\x00'
+p65
+tp66
+Rp67
+sS'>Epi_321'
+p68
+g2
+(g6
+S'n\x00\x00\x00'
+p69
+tp70
+Rp71
+sS'>Epi_326'
+p72
+g2
+(g6
+S'\xd2\x00\x00\x00'
+p73
+tp74
+Rp75
+sS'>Epi_327'
+p76
+g2
+(g6
+S'c\x00\x00\x00'
+p77
+tp78
+Rp79
+sS'>Epi_324'
+p80
+g2
+(g6
+S'\xcb\x00\x00\x00'
+p81
+tp82
+Rp83
+sS'>Epi_325'
+p84
+g2
+(g6
+S'"\x00\x00\x00'
+p85
+tp86
+Rp87
+sS'>Epi_241'
+p88
+g2
+(g6
+S'\xb4\x00\x00\x00'
+p89
+tp90
+Rp91
+sS'>Epi_240'
+p92
+g2
+(g6
+S'\x15\x00\x00\x00'
+p93
+tp94
+Rp95
+sS'>Epi_243'
+p96
+g2
+(g6
+S'F\x00\x00\x00'
+p97
+tp98
+Rp99
+sS'>Epi_242'
+p100
+g2
+(g6
+S'\xa7\x00\x00\x00'
+p101
+tp102
+Rp103
+sS'>Epi_245'
+p104
+g2
+(g6
+S'P\x00\x00\x00'
+p105
+tp106
+Rp107
+sS'>Epi_244'
+p108
+g2
+(g6
+S'\x0e\x00\x00\x00'
+p109
+tp110
+Rp111
+sS'>Epi_247'
+p112
+g2
+(g6
+S'`\x00\x00\x00'
+p113
+tp114
+Rp115
+sS'>Epi_246'
+p116
+g2
+(g6
+S'n\x00\x00\x00'
+p117
+tp118
+Rp119
+sS'>Epi_249'
+p120
+g2
+(g6
+S'=\x00\x00\x00'
+p121
+tp122
+Rp123
+sS'>Epi_248'
+p124
+g2
+(g6
+S'\xd0\x00\x00\x00'
+p125
+tp126
+Rp127
+sS'>Epi_119'
+p128
+g2
+(g6
+S'n\x00\x00\x00'
+p129
+tp130
+Rp131
+sS'>Epi_293'
+p132
+g2
+(g6
+S'f\x00\x00\x00'
+p133
+tp134
+Rp135
+sS'>Epi_290'
+p136
+g2
+(g6
+S'<\x00\x00\x00'
+p137
+tp138
+Rp139
+sS'>Epi_291'
+p140
+g2
+(g6
+S'`\x00\x00\x00'
+p141
+tp142
+Rp143
+sS'>Epi_296'
+p144
+g2
+(g6
+S'\x05\x00\x00\x00'
+p145
+tp146
+Rp147
+sS'>Epi_297'
+p148
+g2
+(g6
+S'\xcd\x00\x00\x00'
+p149
+tp150
+Rp151
+sS'>Epi_294'
+p152
+g2
+(g6
+S'\xaf\x00\x00\x00'
+p153
+tp154
+Rp155
+sS'>Epi_295'
+p156
+g2
+(g6
+S'n\x00\x00\x00'
+p157
+tp158
+Rp159
+sS'>Epi_111'
+p160
+g2
+(g6
+S'!\x00\x00\x00'
+p161
+tp162
+Rp163
+sS'>Epi_110'
+p164
+g2
+(g6
+S'\xbc\x00\x00\x00'
+p165
+tp166
+Rp167
+sS'>Epi_113'
+p168
+g2
+(g6
+S'k\x00\x00\x00'
+p169
+tp170
+Rp171
+sS'>Epi_112'
+p172
+g2
+(g6
+S'k\x00\x00\x00'
+p173
+tp174
+Rp175
+sS'>Epi_115'
+p176
+g2
+(g6
+S'\xb0\x00\x00\x00'
+p177
+tp178
+Rp179
+sS'>Epi_114'
+p180
+g2
+(g6
+S'm\x00\x00\x00'
+p181
+tp182
+Rp183
+sS'>Epi_117'
+p184
+g2
+(g6
+S'\xc3\x00\x00\x00'
+p185
+tp186
+Rp187
+sS'>Epi_116'
+p188
+g2
+(g6
+S'o\x00\x00\x00'
+p189
+tp190
+Rp191
+sS'>Epi_82'
+p192
+g2
+(g6
+S'n\x00\x00\x00'
+p193
+tp194
+Rp195
+sS'>Epi_83'
+p196
+g2
+(g6
+S'n\x00\x00\x00'
+p197
+tp198
+Rp199
+sS'>Epi_80'
+p200
+g2
+(g6
+S'\x0f\x00\x00\x00'
+p201
+tp202
+Rp203
+sS'>Epi_81'
+p204
+g2
+(g6
+S'\x0f\x00\x00\x00'
+p205
+tp206
+Rp207
+sS'>Epi_86'
+p208
+g2
+(g6
+S'\x18\x00\x00\x00'
+p209
+tp210
+Rp211
+sS'>Epi_87'
+p212
+g2
+(g6
+S'k\x00\x00\x00'
+p213
+tp214
+Rp215
+sS'>Epi_84'
+p216
+g2
+(g6
+S'o\x00\x00\x00'
+p217
+tp218
+Rp219
+sS'>Epi_85'
+p220
+g2
+(g6
+S'"\x00\x00\x00'
+p221
+tp222
+Rp223
+sS'>Epi_88'
+p224
+g2
+(g6
+S'e\x00\x00\x00'
+p225
+tp226
+Rp227
+sS'>Epi_89'
+p228
+g2
+(g6
+S'\x91\x00\x00\x00'
+p229
+tp230
+Rp231
+sS'>Epi_209'
+p232
+g2
+(g6
+S'\xb7\x00\x00\x00'
+p233
+tp234
+Rp235
+sS'>Epi_208'
+p236
+g2
+(g6
+S'i\x00\x00\x00'
+p237
+tp238
+Rp239
+sS'>Epi_205'
+p240
+g2
+(g6
+S'i\x00\x00\x00'
+p241
+tp242
+Rp243
+sS'>Epi_204'
+p244
+g2
+(g6
+S'i\x00\x00\x00'
+p245
+tp246
+Rp247
+sS'>Epi_207'
+p248
+g2
+(g6
+S'i\x00\x00\x00'
+p249
+tp250
+Rp251
+sS'>Epi_206'
+p252
+g2
+(g6
+S'i\x00\x00\x00'
+p253
+tp254
+Rp255
+sS'>Epi_201'
+p256
+g2
+(g6
+S'i\x00\x00\x00'
+p257
+tp258
+Rp259
+sS'>Epi_200'
+p260
+g2
+(g6
+S'`\x00\x00\x00'
+p261
+tp262
+Rp263
+sS'>Epi_203'
+p264
+g2
+(g6
+S'i\x00\x00\x00'
+p265
+tp266
+Rp267
+sS'>Epi_202'
+p268
+g2
+(g6
+S'o\x00\x00\x00'
+p269
+tp270
+Rp271
+sS'>Epi_19'
+p272
+g2
+(g6
+S'i\x00\x00\x00'
+p273
+tp274
+Rp275
+sS'>Epi_18'
+p276
+g2
+(g6
+S'I\x00\x00\x00'
+p277
+tp278
+Rp279
+sS'>Epi_15'
+p280
+g2
+(g6
+S'h\x00\x00\x00'
+p281
+tp282
+Rp283
+sS'>Epi_14'
+p284
+g2
+(g6
+S'-\x00\x00\x00'
+p285
+tp286
+Rp287
+sS'>Epi_17'
+p288
+g2
+(g6
+S'l\x00\x00\x00'
+p289
+tp290
+Rp291
+sS'>Epi_16'
+p292
+g2
+(g6
+S'\x95\x00\x00\x00'
+p293
+tp294
+Rp295
+sS'>Epi_11'
+p296
+g2
+(g6
+S'B\x00\x00\x00'
+p297
+tp298
+Rp299
+sS'>Epi_10'
+p300
+g2
+(g6
+S'\xa6\x00\x00\x00'
+p301
+tp302
+Rp303
+sS'>Epi_13'
+p304
+g2
+(g6
+S'\x9e\x00\x00\x00'
+p305
+tp306
+Rp307
+sS'>Epi_12'
+p308
+g2
+(g6
+S'\x87\x00\x00\x00'
+p309
+tp310
+Rp311
+sS'>Epi_278'
+p312
+g2
+(g6
+S'\n\x00\x00\x00'
+p313
+tp314
+Rp315
+sS'>Epi_279'
+p316
+g2
+(g6
+S'z\x00\x00\x00'
+p317
+tp318
+Rp319
+sS'>Epi_270'
+p320
+g2
+(g6
+S'f\x00\x00\x00'
+p321
+tp322
+Rp323
+sS'>Epi_271'
+p324
+g2
+(g6
+S'n\x00\x00\x00'
+p325
+tp326
+Rp327
+sS'>Epi_272'
+p328
+g2
+(g6
+S'\xad\x00\x00\x00'
+p329
+tp330
+Rp331
+sS'>Epi_273'
+p332
+g2
+(g6
+S'n\x00\x00\x00'
+p333
+tp334
+Rp335
+sS'>Epi_274'
+p336
+g2
+(g6
+S'n\x00\x00\x00'
+p337
+tp338
+Rp339
+sS'>Epi_275'
+p340
+g2
+(g6
+S'd\x00\x00\x00'
+p341
+tp342
+Rp343
+sS'>Epi_276'
+p344
+g2
+(g6
+S'd\x00\x00\x00'
+p345
+tp346
+Rp347
+sS'>Epi_277'
+p348
+g2
+(g6
+S'\x84\x00\x00\x00'
+p349
+tp350
+Rp351
+sS'>Epi_155'
+p352
+g2
+(g6
+S'o\x00\x00\x00'
+p353
+tp354
+Rp355
+sS'>Epi_154'
+p356
+g2
+(g6
+S's\x00\x00\x00'
+p357
+tp358
+Rp359
+sS'>Epi_157'
+p360
+g2
+(g6
+S'\x99\x00\x00\x00'
+p361
+tp362
+Rp363
+sS'>Epi_156'
+p364
+g2
+(g6
+S'\xaa\x00\x00\x00'
+p365
+tp366
+Rp367
+sS'>Epi_151'
+p368
+g2
+(g6
+S'i\x00\x00\x00'
+p369
+tp370
+Rp371
+sS'>Epi_150'
+p372
+g2
+(g6
+S'v\x00\x00\x00'
+p373
+tp374
+Rp375
+sS'>Epi_153'
+p376
+g2
+(g6
+S'&\x00\x00\x00'
+p377
+tp378
+Rp379
+sS'>Epi_152'
+p380
+g2
+(g6
+S'&\x00\x00\x00'
+p381
+tp382
+Rp383
+sS'>Epi_159'
+p384
+g2
+(g6
+S'\xb8\x00\x00\x00'
+p385
+tp386
+Rp387
+sS'>Epi_158'
+p388
+g2
+(g6
+S'4\x00\x00\x00'
+p389
+tp390
+Rp391
+sS'>Epi_120'
+p392
+g2
+(g6
+S'm\x00\x00\x00'
+p393
+tp394
+Rp395
+sS'>Epi_121'
+p396
+g2
+(g6
+S'/\x00\x00\x00'
+p397
+tp398
+Rp399
+sS'>Epi_122'
+p400
+g2
+(g6
+S'R\x00\x00\x00'
+p401
+tp402
+Rp403
+sS'>Epi_123'
+p404
+g2
+(g6
+S'U\x00\x00\x00'
+p405
+tp406
+Rp407
+sS'>Epi_124'
+p408
+g2
+(g6
+S'\x01\x00\x00\x00'
+p409
+tp410
+Rp411
+sS'>Epi_125'
+p412
+g2
+(g6
+S'\x01\x00\x00\x00'
+p413
+tp414
+Rp415
+sS'>Epi_126'
+p416
+g2
+(g6
+S'\x01\x00\x00\x00'
+p417
+tp418
+Rp419
+sS'>Epi_127'
+p420
+g2
+(g6
+S'\x08\x00\x00\x00'
+p421
+tp422
+Rp423
+sS'>Epi_128'
+p424
+g2
+(g6
+S'\x1d\x00\x00\x00'
+p425
+tp426
+Rp427
+sS'>Epi_129'
+p428
+g2
+(g6
+S'\xc9\x00\x00\x00'
+p429
+tp430
+Rp431
+sS'>Epi_339'
+p432
+g2
+(g6
+S'\xb3\x00\x00\x00'
+p433
+tp434
+Rp435
+sS'>Epi_338'
+p436
+g2
+(g6
+S'L\x00\x00\x00'
+p437
+tp438
+Rp439
+sS'>Epi_335'
+p440
+g2
+(g6
+S'L\x00\x00\x00'
+p441
+tp442
+Rp443
+sS'>Epi_334'
+p444
+g2
+(g6
+S'L\x00\x00\x00'
+p445
+tp446
+Rp447
+sS'>Epi_337'
+p448
+g2
+(g6
+S'\xab\x00\x00\x00'
+p449
+tp450
+Rp451
+sS'>Epi_336'
+p452
+g2
+(g6
+S'\xcf\x00\x00\x00'
+p453
+tp454
+Rp455
+sS'>Epi_331'
+p456
+g2
+(g6
+S'\x1c\x00\x00\x00'
+p457
+tp458
+Rp459
+sS'>Epi_330'
+p460
+g2
+(g6
+S'i\x00\x00\x00'
+p461
+tp462
+Rp463
+sS'>Epi_333'
+p464
+g2
+(g6
+S'x\x00\x00\x00'
+p465
+tp466
+Rp467
+sS'>Epi_332'
+p468
+g2
+(g6
+S'n\x00\x00\x00'
+p469
+tp470
+Rp471
+sS'>Epi_234'
+p472
+g2
+(g6
+S'\x1e\x00\x00\x00'
+p473
+tp474
+Rp475
+sS'>Epi_235'
+p476
+g2
+(g6
+S'J\x00\x00\x00'
+p477
+tp478
+Rp479
+sS'>Epi_236'
+p480
+g2
+(g6
+S':\x00\x00\x00'
+p481
+tp482
+Rp483
+sS'>Epi_237'
+p484
+g2
+(g6
+S'\x96\x00\x00\x00'
+p485
+tp486
+Rp487
+sS'>Epi_230'
+p488
+g2
+(g6
+S'\xb1\x00\x00\x00'
+p489
+tp490
+Rp491
+sS'>Epi_231'
+p492
+g2
+(g6
+S'n\x00\x00\x00'
+p493
+tp494
+Rp495
+sS'>Epi_232'
+p496
+g2
+(g6
+S'\xb5\x00\x00\x00'
+p497
+tp498
+Rp499
+sS'>Epi_233'
+p500
+g2
+(g6
+S'n\x00\x00\x00'
+p501
+tp502
+Rp503
+sS'>Epi_238'
+p504
+g2
+(g6
+S'C\x00\x00\x00'
+p505
+tp506
+Rp507
+sS'>Epi_239'
+p508
+g2
+(g6
+S'n\x00\x00\x00'
+p509
+tp510
+Rp511
+sS'>Epi_46'
+p512
+g2
+(g6
+S'o\x00\x00\x00'
+p513
+tp514
+Rp515
+sS'>Epi_47'
+p516
+g2
+(g6
+S'2\x00\x00\x00'
+p517
+tp518
+Rp519
+sS'>Epi_44'
+p520
+g2
+(g6
+S'L\x00\x00\x00'
+p521
+tp522
+Rp523
+sS'>Epi_45'
+p524
+g2
+(g6
+S'o\x00\x00\x00'
+p525
+tp526
+Rp527
+sS'>Epi_42'
+p528
+g2
+(g6
+S'$\x00\x00\x00'
+p529
+tp530
+Rp531
+sS'>Epi_43'
+p532
+g2
+(g6
+S'\x1c\x00\x00\x00'
+p533
+tp534
+Rp535
+sS'>Epi_40'
+p536
+g2
+(g6
+S'E\x00\x00\x00'
+p537
+tp538
+Rp539
+sS'>Epi_41'
+p540
+g2
+(g6
+S'n\x00\x00\x00'
+p541
+tp542
+Rp543
+sS'>Epi_48'
+p544
+g2
+(g6
+S'\xc0\x00\x00\x00'
+p545
+tp546
+Rp547
+sS'>Epi_49'
+p548
+g2
+(g6
+S'\x0c\x00\x00\x00'
+p549
+tp550
+Rp551
+sS'>Epi_348'
+p552
+g2
+(g6
+S'n\x00\x00\x00'
+p553
+tp554
+Rp555
+sS'>Epi_349'
+p556
+g2
+(g6
+S'o\x00\x00\x00'
+p557
+tp558
+Rp559
+sS'>Epi_340'
+p560
+g2
+(g6
+S'k\x00\x00\x00'
+p561
+tp562
+Rp563
+sS'>Epi_341'
+p564
+g2
+(g6
+S'k\x00\x00\x00'
+p565
+tp566
+Rp567
+sS'>Epi_342'
+p568
+g2
+(g6
+S'\x17\x00\x00\x00'
+p569
+tp570
+Rp571
+sS'>Epi_343'
+p572
+g2
+(g6
+S'i\x00\x00\x00'
+p573
+tp574
+Rp575
+sS'>Epi_344'
+p576
+g2
+(g6
+S'\xc4\x00\x00\x00'
+p577
+tp578
+Rp579
+sS'>Epi_345'
+p580
+g2
+(g6
+S'\xc1\x00\x00\x00'
+p581
+tp582
+Rp583
+sS'>Epi_346'
+p584
+g2
+(g6
+S'M\x00\x00\x00'
+p585
+tp586
+Rp587
+sS'>Epi_347'
+p588
+g2
+(g6
+S'\xa8\x00\x00\x00'
+p589
+tp590
+Rp591
+sS'>Epi_285'
+p592
+g2
+(g6
+S'n\x00\x00\x00'
+p593
+tp594
+Rp595
+sS'>Epi_284'
+p596
+g2
+(g6
+S'\x19\x00\x00\x00'
+p597
+tp598
+Rp599
+sS'>Epi_287'
+p600
+g2
+(g6
+S'n\x00\x00\x00'
+p601
+tp602
+Rp603
+sS'>Epi_286'
+p604
+g2
+(g6
+S'n\x00\x00\x00'
+p605
+tp606
+Rp607
+sS'>Epi_168'
+p608
+g2
+(g6
+S'f\x00\x00\x00'
+p609
+tp610
+Rp611
+sS'>Epi_169'
+p612
+g2
+(g6
+S'k\x00\x00\x00'
+p613
+tp614
+Rp615
+sS'>Epi_283'
+p616
+g2
+(g6
+S'v\x00\x00\x00'
+p617
+tp618
+Rp619
+sS'>Epi_282'
+p620
+g2
+(g6
+S'h\x00\x00\x00'
+p621
+tp622
+Rp623
+sS'>Epi_164'
+p624
+g2
+(g6
+S'p\x00\x00\x00'
+p625
+tp626
+Rp627
+sS'>Epi_165'
+p628
+g2
+(g6
+S'\xd1\x00\x00\x00'
+p629
+tp630
+Rp631
+sS'>Epi_166'
+p632
+g2
+(g6
+S'\x9f\x00\x00\x00'
+p633
+tp634
+Rp635
+sS'>Epi_167'
+p636
+g2
+(g6
+S'g\x00\x00\x00'
+p637
+tp638
+Rp639
+sS'>Epi_289'
+p640
+g2
+(g6
+S'o\x00\x00\x00'
+p641
+tp642
+Rp643
+sS'>Epi_161'
+p644
+g2
+(g6
+S'o\x00\x00\x00'
+p645
+tp646
+Rp647
+sS'>Epi_162'
+p648
+g2
+(g6
+S'\xa3\x00\x00\x00'
+p649
+tp650
+Rp651
+sS'>Epi_163'
+p652
+g2
+(g6
+S'y\x00\x00\x00'
+p653
+tp654
+Rp655
+sS'>Epi_79'
+p656
+g2
+(g6
+S'o\x00\x00\x00'
+p657
+tp658
+Rp659
+sS'>Epi_78'
+p660
+g2
+(g6
+S'u\x00\x00\x00'
+p661
+tp662
+Rp663
+sS'>Epi_77'
+p664
+g2
+(g6
+S'D\x00\x00\x00'
+p665
+tp666
+Rp667
+sS'>Epi_76'
+p668
+g2
+(g6
+S'n\x00\x00\x00'
+p669
+tp670
+Rp671
+sS'>Epi_75'
+p672
+g2
+(g6
+S'\x98\x00\x00\x00'
+p673
+tp674
+Rp675
+sS'>Epi_74'
+p676
+g2
+(g6
+S'k\x00\x00\x00'
+p677
+tp678
+Rp679
+sS'>Epi_73'
+p680
+g2
+(g6
+S'n\x00\x00\x00'
+p681
+tp682
+Rp683
+sS'>Epi_72'
+p684
+g2
+(g6
+S'n\x00\x00\x00'
+p685
+tp686
+Rp687
+sS'>Epi_71'
+p688
+g2
+(g6
+S'n\x00\x00\x00'
+p689
+tp690
+Rp691
+sS'>Epi_70'
+p692
+g2
+(g6
+S'n\x00\x00\x00'
+p693
+tp694
+Rp695
+sS'>Epi_281'
+p696
+g2
+(g6
+S'n\x00\x00\x00'
+p697
+tp698
+Rp699
+sS'>Epi_280'
+p700
+g2
+(g6
+S'n\x00\x00\x00'
+p701
+tp702
+Rp703
+sS'>Epi_160'
+p704
+g2
+(g6
+S'n\x00\x00\x00'
+p705
+tp706
+Rp707
+sS'>Epi_288'
+p708
+g2
+(g6
+S'j\x00\x00\x00'
+p709
+tp710
+Rp711
+sS'>Epi_304'
+p712
+g2
+(g6
+S'n\x00\x00\x00'
+p713
+tp714
+Rp715
+sS'>Epi_305'
+p716
+g2
+(g6
+S'n\x00\x00\x00'
+p717
+tp718
+Rp719
+sS'>Epi_269'
+p720
+g2
+(g6
+S'{\x00\x00\x00'
+p721
+tp722
+Rp723
+sS'>Epi_307'
+p724
+g2
+(g6
+S'n\x00\x00\x00'
+p725
+tp726
+Rp727
+sS'>Epi_300'
+p728
+g2
+(g6
+S'n\x00\x00\x00'
+p729
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+Rp731
+sS'>Epi_301'
+p732
+g2
+(g6
+S'\\\x00\x00\x00'
+p733
+tp734
+Rp735
+sS'>Epi_302'
+p736
+g2
+(g6
+S'v\x00\x00\x00'
+p737
+tp738
+Rp739
+sS'>Epi_303'
+p740
+g2
+(g6
+S'v\x00\x00\x00'
+p741
+tp742
+Rp743
+sS'>Epi_263'
+p744
+g2
+(g6
+S'\x92\x00\x00\x00'
+p745
+tp746
+Rp747
+sS'>Epi_262'
+p748
+g2
+(g6
+S'\xa9\x00\x00\x00'
+p749
+tp750
+Rp751
+sS'>Epi_261'
+p752
+g2
+(g6
+S'>\x00\x00\x00'
+p753
+tp754
+Rp755
+sS'>Epi_260'
+p756
+g2
+(g6
+S'.\x00\x00\x00'
+p757
+tp758
+Rp759
+sS'>Epi_308'
+p760
+g2
+(g6
+S'6\x00\x00\x00'
+p761
+tp762
+Rp763
+sS'>Epi_309'
+p764
+g2
+(g6
+S'o\x00\x00\x00'
+p765
+tp766
+Rp767
+sS'>Epi_265'
+p768
+g2
+(g6
+S'A\x00\x00\x00'
+p769
+tp770
+Rp771
+sS'>Epi_264'
+p772
+g2
+(g6
+S'n\x00\x00\x00'
+p773
+tp774
+Rp775
+sS'>Epi_133'
+p776
+g2
+(g6
+S'n\x00\x00\x00'
+p777
+tp778
+Rp779
+sS'>Epi_132'
+p780
+g2
+(g6
+S'\x7f\x00\x00\x00'
+p781
+tp782
+Rp783
+sS'>Epi_131'
+p784
+g2
+(g6
+S'\x18\x00\x00\x00'
+p785
+tp786
+Rp787
+sS'>Epi_130'
+p788
+g2
+(g6
+S'[\x00\x00\x00'
+p789
+tp790
+Rp791
+sS'>Epi_137'
+p792
+g2
+(g6
+S'n\x00\x00\x00'
+p793
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+Rp795
+sS'>Epi_136'
+p796
+g2
+(g6
+S'n\x00\x00\x00'
+p797
+tp798
+Rp799
+sS'>Epi_135'
+p800
+g2
+(g6
+S'\x80\x00\x00\x00'
+p801
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+Rp803
+sS'>Epi_134'
+p804
+g2
+(g6
+S'n\x00\x00\x00'
+p805
+tp806
+Rp807
+sS'>Epi_139'
+p808
+g2
+(g6
+S'v\x00\x00\x00'
+p809
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+Rp811
+sS'>Epi_138'
+p812
+g2
+(g6
+S'n\x00\x00\x00'
+p813
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+Rp815
+sS'>Epi_227'
+p816
+g2
+(g6
+S'?\x00\x00\x00'
+p817
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+Rp819
+sS'>Epi_226'
+p820
+g2
+(g6
+S'\x81\x00\x00\x00'
+p821
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+Rp823
+sS'>Epi_225'
+p824
+g2
+(g6
+S'%\x00\x00\x00'
+p825
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+Rp827
+sS'>Epi_224'
+p828
+g2
+(g6
+S'\x8d\x00\x00\x00'
+p829
+tp830
+Rp831
+sS'>Epi_223'
+p832
+g2
+(g6
+S'+\x00\x00\x00'
+p833
+tp834
+Rp835
+sS'>Epi_258'
+p836
+g2
+(g6
+S'q\x00\x00\x00'
+p837
+tp838
+Rp839
+sS'>Epi_188'
+p840
+g2
+(g6
+S'\xa1\x00\x00\x00'
+p841
+tp842
+Rp843
+sS'>Epi_189'
+p844
+g2
+(g6
+S'D\x00\x00\x00'
+p845
+tp846
+Rp847
+sS'>Epi_186'
+p848
+g2
+(g6
+S'n\x00\x00\x00'
+p849
+tp850
+Rp851
+sS'>Epi_187'
+p852
+g2
+(g6
+S'Y\x00\x00\x00'
+p853
+tp854
+Rp855
+sS'>Epi_184'
+p856
+g2
+(g6
+S'n\x00\x00\x00'
+p857
+tp858
+Rp859
+sS'>Epi_259'
+p860
+g2
+(g6
+S')\x00\x00\x00'
+p861
+tp862
+Rp863
+sS'>Epi_182'
+p864
+g2
+(g6
+S'k\x00\x00\x00'
+p865
+tp866
+Rp867
+sS'>Epi_183'
+p868
+g2
+(g6
+S'\x13\x00\x00\x00'
+p869
+tp870
+Rp871
+sS'>Epi_229'
+p872
+g2
+(g6
+S'\x10\x00\x00\x00'
+p873
+tp874
+Rp875
+sS'>Epi_228'
+p876
+g2
+(g6
+S'v\x00\x00\x00'
+p877
+tp878
+Rp879
+sS'>Epi_33'
+p880
+g2
+(g6
+S'k\x00\x00\x00'
+p881
+tp882
+Rp883
+sS'>Epi_32'
+p884
+g2
+(g6
+S'\xae\x00\x00\x00'
+p885
+tp886
+Rp887
+sS'>Epi_31'
+p888
+g2
+(g6
+S'\x8a\x00\x00\x00'
+p889
+tp890
+Rp891
+sS'>Epi_30'
+p892
+g2
+(g6
+S'a\x00\x00\x00'
+p893
+tp894
+Rp895
+sS'>Epi_37'
+p896
+g2
+(g6
+S'\x0f\x00\x00\x00'
+p897
+tp898
+Rp899
+sS'>Epi_36'
+p900
+g2
+(g6
+S'\x0f\x00\x00\x00'
+p901
+tp902
+Rp903
+sS'>Epi_35'
+p904
+g2
+(g6
+S'\xc8\x00\x00\x00'
+p905
+tp906
+Rp907
+sS'>Epi_34'
+p908
+g2
+(g6
+S'c\x00\x00\x00'
+p909
+tp910
+Rp911
+sS'>Epi_39'
+p912
+g2
+(g6
+S'\xb6\x00\x00\x00'
+p913
+tp914
+Rp915
+sS'>Epi_38'
+p916
+g2
+(g6
+S't\x00\x00\x00'
+p917
+tp918
+Rp919
+sS'>Epi_250'
+p920
+g2
+(g6
+S'\xb2\x00\x00\x00'
+p921
+tp922
+Rp923
+sS'>Epi_251'
+p924
+g2
+(g6
+S'W\x00\x00\x00'
+p925
+tp926
+Rp927
+sS'>Epi_353'
+p928
+g2
+(g6
+S'0\x00\x00\x00'
+p929
+tp930
+Rp931
+sS'>Epi_352'
+p932
+g2
+(g6
+S'n\x00\x00\x00'
+p933
+tp934
+Rp935
+sS'>Epi_351'
+p936
+g2
+(g6
+S'N\x00\x00\x00'
+p937
+tp938
+Rp939
+sS'>Epi_350'
+p940
+g2
+(g6
+S'\x8f\x00\x00\x00'
+p941
+tp942
+Rp943
+sS'>Epi_354'
+p944
+g2
+(g6
+S'V\x00\x00\x00'
+p945
+tp946
+Rp947
+sS'>Epi_222'
+p948
+g2
+(g6
+S'3\x00\x00\x00'
+p949
+tp950
+Rp951
+sS'>Epi_221'
+p952
+g2
+(g6
+S'S\x00\x00\x00'
+p953
+tp954
+Rp955
+sS'>Epi_220'
+p956
+g2
+(g6
+S'\x97\x00\x00\x00'
+p957
+tp958
+Rp959
+sS'>Epi_185'
+p960
+g2
+(g6
+S'(\x00\x00\x00'
+p961
+tp962
+Rp963
+sS'>Epi_179'
+p964
+g2
+(g6
+S'\x8b\x00\x00\x00'
+p965
+tp966
+Rp967
+sS'>Epi_178'
+p968
+g2
+(g6
+S'v\x00\x00\x00'
+p969
+tp970
+Rp971
+sS'>Epi_177'
+p972
+g2
+(g6
+S'\r\x00\x00\x00'
+p973
+tp974
+Rp975
+sS'>Epi_176'
+p976
+g2
+(g6
+S'\x15\x00\x00\x00'
+p977
+tp978
+Rp979
+sS'>Epi_175'
+p980
+g2
+(g6
+S'9\x00\x00\x00'
+p981
+tp982
+Rp983
+sS'>Epi_174'
+p984
+g2
+(g6
+S'\x0c\x00\x00\x00'
+p985
+tp986
+Rp987
+sS'>Epi_173'
+p988
+g2
+(g6
+S'\xa4\x00\x00\x00'
+p989
+tp990
+Rp991
+sS'>Epi_172'
+p992
+g2
+(g6
+S'#\x00\x00\x00'
+p993
+tp994
+Rp995
+sS'>Epi_171'
+p996
+g2
+(g6
+S'#\x00\x00\x00'
+p997
+tp998
+Rp999
+sS'>Epi_170'
+p1000
+g2
+(g6
+S'#\x00\x00\x00'
+p1001
+tp1002
+Rp1003
+sS'>Epi_180'
+p1004
+g2
+(g6
+S'v\x00\x00\x00'
+p1005
+tp1006
+Rp1007
+sS'>Epi_181'
+p1008
+g2
+(g6
+S'\xac\x00\x00\x00'
+p1009
+tp1010
+Rp1011
+sS'>Epi_68'
+p1012
+g2
+(g6
+S'k\x00\x00\x00'
+p1013
+tp1014
+Rp1015
+sS'>Epi_69'
+p1016
+g2
+(g6
+S'\xa2\x00\x00\x00'
+p1017
+tp1018
+Rp1019
+sS'>Epi_64'
+p1020
+g2
+(g6
+S'G\x00\x00\x00'
+p1021
+tp1022
+Rp1023
+sS'>Epi_65'
+p1024
+g2
+(g6
+S'G\x00\x00\x00'
+p1025
+tp1026
+Rp1027
+sS'>Epi_66'
+p1028
+g2
+(g6
+S'7\x00\x00\x00'
+p1029
+tp1030
+Rp1031
+sS'>Epi_67'
+p1032
+g2
+(g6
+S'l\x00\x00\x00'
+p1033
+tp1034
+Rp1035
+sS'>Epi_60'
+p1036
+g2
+(g6
+S'\xc2\x00\x00\x00'
+p1037
+tp1038
+Rp1039
+sS'>Epi_61'
+p1040
+g2
+(g6
+S'\x86\x00\x00\x00'
+p1041
+tp1042
+Rp1043
+sS'>Epi_62'
+p1044
+g2
+(g6
+S'\xa5\x00\x00\x00'
+p1045
+tp1046
+Rp1047
+sS'>Epi_63'
+p1048
+g2
+(g6
+S'\x14\x00\x00\x00'
+p1049
+tp1050
+Rp1051
+sS'>Epi_9'
+p1052
+g2
+(g6
+S'N\x00\x00\x00'
+p1053
+tp1054
+Rp1055
+sS'>Epi_8'
+p1056
+g2
+(g6
+S'N\x00\x00\x00'
+p1057
+tp1058
+Rp1059
+sS'>Epi_1'
+p1060
+g2
+(g6
+S'N\x00\x00\x00'
+p1061
+tp1062
+Rp1063
+sS'>Epi_0'
+p1064
+g2
+(g6
+S'2\x00\x00\x00'
+p1065
+tp1066
+Rp1067
+sS'>Epi_3'
+p1068
+g2
+(g6
+S'\x9c\x00\x00\x00'
+p1069
+tp1070
+Rp1071
+sS'>Epi_2'
+p1072
+g2
+(g6
+S'\x88\x00\x00\x00'
+p1073
+tp1074
+Rp1075
+sS'>Epi_5'
+p1076
+g2
+(g6
+S'\t\x00\x00\x00'
+p1077
+tp1078
+Rp1079
+sS'>Epi_4'
+p1080
+g2
+(g6
+S'n\x00\x00\x00'
+p1081
+tp1082
+Rp1083
+sS'>Epi_7'
+p1084
+g2
+(g6
+S'\xba\x00\x00\x00'
+p1085
+tp1086
+Rp1087
+sS'>Epi_6'
+p1088
+g2
+(g6
+S'\xbf\x00\x00\x00'
+p1089
+tp1090
+Rp1091
+sS'>Epi_292'
+p1092
+g2
+(g6
+S':\x00\x00\x00'
+p1093
+tp1094
+Rp1095
+sS'>Epi_118'
+p1096
+g2
+(g6
+S' \x00\x00\x00'
+p1097
+tp1098
+Rp1099
+sS'>Epi_317'
+p1100
+g2
+(g6
+S'f\x00\x00\x00'
+p1101
+tp1102
+Rp1103
+sS'>Epi_316'
+p1104
+g2
+(g6
+S'^\x00\x00\x00'
+p1105
+tp1106
+Rp1107
+sS'>Epi_315'
+p1108
+g2
+(g6
+S'j\x00\x00\x00'
+p1109
+tp1110
+Rp1111
+sS'>Epi_314'
+p1112
+g2
+(g6
+S'v\x00\x00\x00'
+p1113
+tp1114
+Rp1115
+sS'>Epi_313'
+p1116
+g2
+(g6
+S'h\x00\x00\x00'
+p1117
+tp1118
+Rp1119
+sS'>Epi_312'
+p1120
+g2
+(g6
+S'\x02\x00\x00\x00'
+p1121
+tp1122
+Rp1123
+sS'>Epi_311'
+p1124
+g2
+(g6
+S'\x83\x00\x00\x00'
+p1125
+tp1126
+Rp1127
+sS'>Epi_310'
+p1128
+g2
+(g6
+S']\x00\x00\x00'
+p1129
+tp1130
+Rp1131
+sS'>Epi_256'
+p1132
+g2
+(g6
+S'\x03\x00\x00\x00'
+p1133
+tp1134
+Rp1135
+sS'>Epi_257'
+p1136
+g2
+(g6
+S'\xb9\x00\x00\x00'
+p1137
+tp1138
+Rp1139
+sS'>Epi_254'
+p1140
+g2
+(g6
+S'\x8c\x00\x00\x00'
+p1141
+tp1142
+Rp1143
+sS'>Epi_255'
+p1144
+g2
+(g6
+S'n\x00\x00\x00'
+p1145
+tp1146
+Rp1147
+sS'>Epi_252'
+p1148
+g2
+(g6
+S'~\x00\x00\x00'
+p1149
+tp1150
+Rp1151
+sS'>Epi_253'
+p1152
+g2
+(g6
+S'\xc5\x00\x00\x00'
+p1153
+tp1154
+Rp1155
+sS'>Epi_319'
+p1156
+g2
+(g6
+S'n\x00\x00\x00'
+p1157
+tp1158
+Rp1159
+sS'>Epi_318'
+p1160
+g2
+(g6
+S'\x0b\x00\x00\x00'
+p1161
+tp1162
+Rp1163
+sS'>Epi_298'
+p1164
+g2
+(g6
+S'8\x00\x00\x00'
+p1165
+tp1166
+Rp1167
+sS'>Epi_299'
+p1168
+g2
+(g6
+S'8\x00\x00\x00'
+p1169
+tp1170
+Rp1171
+sS'>Epi_106'
+p1172
+g2
+(g6
+S'b\x00\x00\x00'
+p1173
+tp1174
+Rp1175
+sS'>Epi_107'
+p1176
+g2
+(g6
+S'o\x00\x00\x00'
+p1177
+tp1178
+Rp1179
+sS'>Epi_104'
+p1180
+g2
+(g6
+S'\xbd\x00\x00\x00'
+p1181
+tp1182
+Rp1183
+sS'>Epi_105'
+p1184
+g2
+(g6
+S'_\x00\x00\x00'
+p1185
+tp1186
+Rp1187
+sS'>Epi_102'
+p1188
+g2
+(g6
+S'n\x00\x00\x00'
+p1189
+tp1190
+Rp1191
+sS'>Epi_103'
+p1192
+g2
+(g6
+S'v\x00\x00\x00'
+p1193
+tp1194
+Rp1195
+sS'>Epi_100'
+p1196
+g2
+(g6
+S'k\x00\x00\x00'
+p1197
+tp1198
+Rp1199
+sS'>Epi_101'
+p1200
+g2
+(g6
+S"'\x00\x00\x00"
+p1201
+tp1202
+Rp1203
+sS'>Epi_108'
+p1204
+g2
+(g6
+S'E\x00\x00\x00'
+p1205
+tp1206
+Rp1207
+sS'>Epi_109'
+p1208
+g2
+(g6
+S'\xbe\x00\x00\x00'
+p1209
+tp1210
+Rp1211
+sS'>Epi_95'
+p1212
+g2
+(g6
+S'A\x00\x00\x00'
+p1213
+tp1214
+Rp1215
+sS'>Epi_94'
+p1216
+g2
+(g6
+S'Q\x00\x00\x00'
+p1217
+tp1218
+Rp1219
+sS'>Epi_97'
+p1220
+g2
+(g6
+S'4\x00\x00\x00'
+p1221
+tp1222
+Rp1223
+sS'>Epi_96'
+p1224
+g2
+(g6
+S'*\x00\x00\x00'
+p1225
+tp1226
+Rp1227
+sS'>Epi_91'
+p1228
+g2
+(g6
+S'\x9b\x00\x00\x00'
+p1229
+tp1230
+Rp1231
+sS'>Epi_90'
+p1232
+g2
+(g6
+S'@\x00\x00\x00'
+p1233
+tp1234
+Rp1235
+sS'>Epi_93'
+p1236
+g2
+(g6
+S'\xce\x00\x00\x00'
+p1237
+tp1238
+Rp1239
+sS'>Epi_92'
+p1240
+g2
+(g6
+S'n\x00\x00\x00'
+p1241
+tp1242
+Rp1243
+sS'>Epi_99'
+p1244
+g2
+(g6
+S'K\x00\x00\x00'
+p1245
+tp1246
+Rp1247
+sS'>Epi_98'
+p1248
+g2
+(g6
+S'v\x00\x00\x00'
+p1249
+tp1250
+Rp1251
+sS'>Epi_218'
+p1252
+g2
+(g6
+S'1\x00\x00\x00'
+p1253
+tp1254
+Rp1255
+sS'>Epi_219'
+p1256
+g2
+(g6
+S'k\x00\x00\x00'
+p1257
+tp1258
+Rp1259
+sS'>Epi_212'
+p1260
+g2
+(g6
+S'n\x00\x00\x00'
+p1261
+tp1262
+Rp1263
+sS'>Epi_213'
+p1264
+g2
+(g6
+S'n\x00\x00\x00'
+p1265
+tp1266
+Rp1267
+sS'>Epi_210'
+p1268
+g2
+(g6
+S'\x9a\x00\x00\x00'
+p1269
+tp1270
+Rp1271
+sS'>Epi_211'
+p1272
+g2
+(g6
+S'T\x00\x00\x00'
+p1273
+tp1274
+Rp1275
+sS'>Epi_216'
+p1276
+g2
+(g6
+S'\x85\x00\x00\x00'
+p1277
+tp1278
+Rp1279
+sS'>Epi_217'
+p1280
+g2
+(g6
+S'o\x00\x00\x00'
+p1281
+tp1282
+Rp1283
+sS'>Epi_214'
+p1284
+g2
+(g6
+S'\xbb\x00\x00\x00'
+p1285
+tp1286
+Rp1287
+sS'>Epi_215'
+p1288
+g2
+(g6
+S'|\x00\x00\x00'
+p1289
+tp1290
+Rp1291
+sS'>Epi_191'
+p1292
+g2
+(g6
+S'\x12\x00\x00\x00'
+p1293
+tp1294
+Rp1295
+sS'>Epi_190'
+p1296
+g2
+(g6
+S'\x82\x00\x00\x00'
+p1297
+tp1298
+Rp1299
+sS'>Epi_193'
+p1300
+g2
+(g6
+S',\x00\x00\x00'
+p1301
+tp1302
+Rp1303
+sS'>Epi_192'
+p1304
+g2
+(g6
+S'}\x00\x00\x00'
+p1305
+tp1306
+Rp1307
+sS'>Epi_195'
+p1308
+g2
+(g6
+S'\x94\x00\x00\x00'
+p1309
+tp1310
+Rp1311
+sS'>Epi_194'
+p1312
+g2
+(g6
+S'\xa0\x00\x00\x00'
+p1313
+tp1314
+Rp1315
+sS'>Epi_197'
+p1316
+g2
+(g6
+S'X\x00\x00\x00'
+p1317
+tp1318
+Rp1319
+sS'>Epi_196'
+p1320
+g2
+(g6
+S'\x8e\x00\x00\x00'
+p1321
+tp1322
+Rp1323
+sS'>Epi_199'
+p1324
+g2
+(g6
+S'\xc7\x00\x00\x00'
+p1325
+tp1326
+Rp1327
+sS'>Epi_198'
+p1328
+g2
+(g6
+S'\x11\x00\x00\x00'
+p1329
+tp1330
+Rp1331
+sS'>Epi_20'
+p1332
+g2
+(g6
+S'\xca\x00\x00\x00'
+p1333
+tp1334
+Rp1335
+sS'>Epi_21'
+p1336
+g2
+(g6
+S'O\x00\x00\x00'
+p1337
+tp1338
+Rp1339
+sS'>Epi_22'
+p1340
+g2
+(g6
+S'\x0e\x00\x00\x00'
+p1341
+tp1342
+Rp1343
+sS'>Epi_23'
+p1344
+g2
+(g6
+S'1\x00\x00\x00'
+p1345
+tp1346
+Rp1347
+sS'>Epi_24'
+p1348
+g2
+(g6
+S'u\x00\x00\x00'
+p1349
+tp1350
+Rp1351
+sS'>Epi_25'
+p1352
+g2
+(g6
+S'\x1f\x00\x00\x00'
+p1353
+tp1354
+Rp1355
+sS'>Epi_26'
+p1356
+g2
+(g6
+S'j\x00\x00\x00'
+p1357
+tp1358
+Rp1359
+sS'>Epi_27'
+p1360
+g2
+(g6
+S'o\x00\x00\x00'
+p1361
+tp1362
+Rp1363
+sS'>Epi_28'
+p1364
+g2
+(g6
+S'\x1a\x00\x00\x00'
+p1365
+tp1366
+Rp1367
+sS'>Epi_29'
+p1368
+g2
+(g6
+S'\x89\x00\x00\x00'
+p1369
+tp1370
+Rp1371
+sS'>Epi_306'
+p1372
+g2
+(g6
+S'9\x00\x00\x00'
+p1373
+tp1374
+Rp1375
+sS'>Epi_268'
+p1376
+g2
+(g6
+S'I\x00\x00\x00'
+p1377
+tp1378
+Rp1379
+sS'>Epi_267'
+p1380
+g2
+(g6
+S'h\x00\x00\x00'
+p1381
+tp1382
+Rp1383
+sS'>Epi_266'
+p1384
+g2
+(g6
+S'h\x00\x00\x00'
+p1385
+tp1386
+Rp1387
+sS'>Epi_142'
+p1388
+g2
+(g6
+S'H\x00\x00\x00'
+p1389
+tp1390
+Rp1391
+sS'>Epi_143'
+p1392
+g2
+(g6
+S'\xc6\x00\x00\x00'
+p1393
+tp1394
+Rp1395
+sS'>Epi_140'
+p1396
+g2
+(g6
+S'\x9d\x00\x00\x00'
+p1397
+tp1398
+Rp1399
+sS'>Epi_141'
+p1400
+g2
+(g6
+S'5\x00\x00\x00'
+p1401
+tp1402
+Rp1403
+sS'>Epi_146'
+p1404
+g2
+(g6
+S'w\x00\x00\x00'
+p1405
+tp1406
+Rp1407
+sS'>Epi_147'
+p1408
+g2
+(g6
+S'\x90\x00\x00\x00'
+p1409
+tp1410
+Rp1411
+sS'>Epi_144'
+p1412
+g2
+(g6
+S'F\x00\x00\x00'
+p1413
+tp1414
+Rp1415
+sS'>Epi_145'
+p1416
+g2
+(g6
+S'\x1b\x00\x00\x00'
+p1417
+tp1418
+Rp1419
+sS'>Epi_148'
+p1420
+g2
+(g6
+S'\x07\x00\x00\x00'
+p1421
+tp1422
+Rp1423
+sS'>Epi_149'
+p1424
+g2
+(g6
+S'\x06\x00\x00\x00'
+p1425
+tp1426
+Rp1427
+s.
\ No newline at end of file
diff --git a/scripts/data_prepare.py b/scripts/data_prepare.py
index ff59e4b..087e478 100644
--- a/scripts/data_prepare.py
+++ b/scripts/data_prepare.py
@@ -58,3 +58,46 @@ def make_shuffled_nega(cdr3, epi, labels, epi_id):
     }
 
 
+def get_cluster(dataset_name, split):
+    if (dataset_name in ['seqlevel_data']) and split == 'cv-new_epitope':
+        cluster_path = './data/cluster/seqlevel_epi_cluster_0.5.pkl'
+        with open(cluster_path, 'rb') as f:
+            epi2cluster = pickle.load(f, encoding='iso-8859-1')
+        epi2cluster = {int(k.split('_')[-1]):v for k, v in epi2cluster.items()}
+        return epi2cluster
+    elif dataset_name == 'reslevel_data':
+        cluster_path_dict = {
+            'cdr3': './data/cluster/reslevel_cdr3_cluster_0.2.pkl',
+            'epi': './data/cluster/reslevel_epi_cluster_0.2.pkl',
+        }
+        cdr32cluster, epi2cluster = {}, {}
+        if ('new_cdr3' in split) or ('both_new' in split):
+            with open(cluster_path_dict['cdr3'], 'rb') as f:
+                cdr32cluster = pickle.load(f, encoding='iso-8859-1')
+        if ('new_epi' in split) or ('both_new' in split):
+            with open(cluster_path_dict['epi'], 'rb') as f:
+                epi2cluster = pickle.load(f, encoding='iso-8859-1')
+    else:
+        raise ValueError('dataset_name {} not supported'.format(dataset_name))
+    return cdr32cluster, epi2cluster
+
+
+def get_split(split_type, dataset_name, all_cdr3, all_epi):
+    cdr32cluster, epi2cluster = get_cluster(dataset_name, split_type)
+
+    assert split_type in ['cv-both_new', 'cv-new_cdr3', 'cv-new_epi']
+    kfold = GroupKFold(3) if split_type == 'cv-both_new' else GroupKFold(5)
+    if len(cdr32cluster) != 0:  # new_cdr3, both_new
+        cdr3_group_id = [cdr32cluster[cdr3_this] for cdr3_this in all_cdr3]
+        split_cdr3 = list(kfold.split(all_cdr3, groups=cdr3_group_id))
+        split = split_cdr3
+    if len(epi2cluster) != 0:  # new_epi, both_new
+        epi_group_id = [epi2cluster[epi_this] for epi_this in all_epi]
+        split_epi = list(kfold.split(all_epi, groups=epi_group_id))
+        split = split_epi
+    if split_type == 'cv-both_new':
+        split = [[np.intersect1d(fold_tcr[0], fold_epi[0]), np.intersect1d(fold_tcr[1], fold_epi[1])]
+            for fold_tcr, fold_epi in zip(split_cdr3, split_epi)]
+    
+    return split
+    
\ No newline at end of file
diff --git a/scripts/data_process.py b/scripts/data_process.py
index e7e4b5b..fb4cbd9 100644
--- a/scripts/data_process.py
+++ b/scripts/data_process.py
@@ -8,6 +8,7 @@
 from models import AutoEncoder
 base_data_dir = './all_data/'
 
+device = torch.device('cuda' if torch.cuda.is_available() else 'cpu')
 
 def GetBlosumMat(residues_list):
     n_residues = len(residues_list)  # the number of amino acids _ 'X'
@@ -74,7 +75,7 @@ def get_numbering(seqs, ):
     
     # # using ANARCI to get numbering file
     # cmd = ("conda run -n teim "  # this environment name should be the same as the one you install anarci
-    cmd = (" ANARCI"
+    cmd = ("ANARCI"
             " -i tmp_faketcr.fasta  -o tmp_align --csv -p 24")
     res = os.system(cmd)
     
@@ -105,7 +106,7 @@ def get_numbering(seqs, ):
     return df.loc[seqs, 'cdr3_align'].values
 
 
-def load_ae_model(tokenizer, path='./ckpt/epi_ae.ckpt'):
+def load_ae_model(tokenizer, path='./ckpt/epi_ae.ckpt',):
     # tokenizer = Tokenizer()
     ## load model
     model_args = dict(
@@ -117,7 +118,7 @@ def load_ae_model(tokenizer, path='./ckpt/epi_ae.ckpt'):
     model.eval()
 
     ## load weights
-    state_dict = torch.load(path)
+    state_dict = torch.load(path, map_location=device)
     state_dict = {k[6:]:v for k, v in state_dict.items()}
     model.load_state_dict(state_dict)
     return model
diff --git a/scripts/inference_res.py b/scripts/inference_res.py
index e6d3eba..6fe8a15 100644
--- a/scripts/inference_res.py
+++ b/scripts/inference_res.py
@@ -20,7 +20,7 @@
 import warnings
 warnings.filterwarnings("ignore")
 
-os.environ['CUDA_VISIBLE_DEVICES'] = '2'
+device = torch.device('cuda' if torch.cuda.is_available() else 'cpu')
 
 
 class MyDataSet(torch.utils.data.Dataset):
@@ -289,7 +289,7 @@ def __init__(self, ):
             'use_vae': False,
         }
         self.model, self.tokenizer = self.load_pdb_model()
-        self.model = self.model.cuda()
+        self.model = self.model.to(device)
         self.model.eval()
 
     def load_pdb_model(self):
@@ -302,7 +302,7 @@ def load_pdb_model(self):
                 model_type = self.data_mode['model_type']
             ), lr=0.1, weight_decay=0.1, model=deepcopy(base_model))
 
-        model.load_state_dict(torch.load(pdb_model_path)['state_dict'])
+        model.load_state_dict(torch.load(pdb_model_path, map_location=device)['state_dict'])
 
         n_para = np.sum([a.numel() for a in model.parameters()])
         print('Number of paramters', n_para)
@@ -340,9 +340,9 @@ def forward(self, encoding_cdr3, encoding_epi, epi_vec):
         pred = []
         for batch in np.arange(0, len(encoding_cdr3) // bs + 1):
             idx_end = min((batch+1)*bs, len(encoding_cdr3))
-            input_cdr3 = torch.Tensor(encoding_cdr3[batch*bs:idx_end, ...]).cuda()
-            input_epi = torch.Tensor(encoding_epi[batch*bs:idx_end, ...]).cuda()
-            input_vec = torch.Tensor(epi_vec[batch*bs:idx_end, ...]).cuda()
+            input_cdr3 = torch.Tensor(encoding_cdr3[batch*bs:idx_end, ...]).to(device)
+            input_epi = torch.Tensor(encoding_epi[batch*bs:idx_end, ...]).to(device)
+            input_vec = torch.Tensor(epi_vec[batch*bs:idx_end, ...]).to(device)
             pred_batch = self.model([input_cdr3, input_epi, input_vec])
             pred_batch = pred_batch.cpu().detach().numpy()
             pred.extend(pred_batch)
diff --git a/scripts/inference_seq.py b/scripts/inference_seq.py
index ecd5a1e..468c39d 100644
--- a/scripts/inference_seq.py
+++ b/scripts/inference_seq.py
@@ -14,7 +14,7 @@
 from sklearn.metrics import roc_auc_score, average_precision_score
 import warnings
 warnings.filterwarnings("ignore")
-os.environ['CUDA_VISIBLE_DEVICES'] = '0'
+device = torch.device('cuda' if torch.cuda.is_available() else 'cpu')
 
 
 class BdTrainerSystem(pl.LightningModule):
@@ -103,7 +103,7 @@ def get_scores(self, y_true, y_pred, y_mask):
 class BindPredictor:
     def __init__(self, path='./ckpt/teim_seq.ckpt'):
         self.model = BdTrainerSystem.load_from_checkpoint(path)
-        self.model = self.model.cuda()
+        self.model = self.model.to(device)
         self.model.eval()
         self.tokenizer = Tokenizer()
 
@@ -124,9 +124,9 @@ def forward(self, encoding_cdr3, encoding_epi, epi_vec):
         pred = []
         for batch in np.arange(0, len(encoding_cdr3) // bs + 1):
             idx_end = min((batch+1)*bs, len(encoding_cdr3))
-            input_cdr3 = torch.Tensor(encoding_cdr3[batch*bs:idx_end, ...]).cuda()
-            input_epi = torch.Tensor(encoding_epi[batch*bs:idx_end, ...]).cuda()
-            input_vec = torch.Tensor(epi_vec[batch*bs:idx_end, ...]).cuda()
+            input_cdr3 = torch.Tensor(encoding_cdr3[batch*bs:idx_end, ...]).to(device)
+            input_epi = torch.Tensor(encoding_epi[batch*bs:idx_end, ...]).to(device)
+            input_vec = torch.Tensor(epi_vec[batch*bs:idx_end, ...]).to(device)
             pred_batch = self.model([input_cdr3, input_epi, input_vec])
             pred_batch = pred_batch.cpu().detach().numpy()
             pred.extend(pred_batch)