diff --git a/CMakeLists.txt b/CMakeLists.txt
index a725f897..821e1039 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -119,8 +119,6 @@ target_compile_features(hictk_project_options INTERFACE "cxx_std_${CMAKE_CXX_STA
 target_compile_definitions(hictk_project_options INTERFACE FMT_HEADER_ONLY FMT_ENFORCE_COMPILE_STRING)
 # Tweak spdlog
 target_compile_definitions(hictk_project_options INTERFACE SPDLOG_FMT_EXTERNAL)
-#Tweak xxHash
-target_compile_definitions(hictk_project_options INTERFACE XXH_INLINE_ALL)
 
 if(WIN32)
   target_compile_definitions(hictk_project_options INTERFACE NOMINMAX _CRT_SECURE_NO_WARNINGS)
diff --git a/cmake/modules/FindxxHash.cmake b/cmake/modules/FindxxHash.cmake
deleted file mode 100644
index 5829494b..00000000
--- a/cmake/modules/FindxxHash.cmake
+++ /dev/null
@@ -1,45 +0,0 @@
-# Copyright (C) 2023 Roberto Rossini <roberros@uio.no>
-#
-# SPDX-License-Identifier: MIT
-
-find_package(PkgConfig)
-pkg_check_modules(PC_xxHash QUIET xxHash)
-
-find_path(
-  xxHash_INCLUDE_DIR
-  NAMES xxhash.h
-  PATHS ${PC_xxHash_INCLUDE_DIRS}
-  PATH_SUFFIXES include)
-find_library(
-  xxHash_LIBRARY
-  NAMES xxhash
-  PATHS ${PC_xxHash_LIBRARY_DIRS}
-  PATH_SUFFIXES lib)
-
-set(xxHash_VERSION ${PC_xxHash_VERSION})
-
-include(FindPackageHandleStandardArgs)
-find_package_handle_standard_args(
-  xxHash
-  FOUND_VAR xxHash_FOUND
-  REQUIRED_VARS xxHash_LIBRARY xxHash_INCLUDE_DIR
-  VERSION_VAR xxHash_VERSION)
-
-if(xxHash_FOUND)
-  set(xxHash_LIBRARIES ${xxHash_LIBRARY})
-  set(xxHash_INCLUDE_DIRS ${xxHash_INCLUDE_DIR})
-  set(xxHash_DEFINITIONS ${PC_xxHash_CFLAGS_OTHER})
-endif()
-
-if(xxHash_FOUND AND NOT TARGET xxHash::xxhash)
-  add_library(xxHash::xxhash UNKNOWN IMPORTED)
-  set_target_properties(
-    xxHash::xxhash
-    PROPERTIES IMPORTED_LOCATION "${xxHash_LIBRARY}"
-               INTERFACE_COMPILE_OPTIONS "${PC_xxHash_CFLAGS_OTHER}"
-               INTERFACE_INCLUDE_DIRECTORIES "${xxHash_INCLUDE_DIR}")
-endif()
-
-mark_as_advanced(xxHash_INCLUDE_DIR xxHash_LIBRARY)
-
-set(xxHash_VERSION_STRING ${xxHash_VERSION})