diff --git a/src/ontology/Makefile b/src/ontology/Makefile index 3951dcad80..f81e195d50 100644 --- a/src/ontology/Makefile +++ b/src/ontology/Makefile @@ -427,8 +427,9 @@ mirror-cl: | $(TMPDIR) .PHONY: mirror-go .PRECIOUS: $(MIRRORDIR)/go.owl mirror-go: | $(TMPDIR) - if [ $(MIR) = true ] && [ $(IMP) = true ]; then curl -L $(OBOBASE)/go/go-base.owl --create-dirs -o $(MIRRORDIR)/go.owl --retry 4 --max-time 200 &&\ - $(ROBOT) convert -i $(MIRRORDIR)/go.owl -o $@.tmp.owl && mv $@.tmp.owl $(TMPDIR)/$@.owl; fi + if [ $(MIR) = true ] && [ $(IMP) = true ]; then $(ROBOT) convert -I http://purl.obolibrary.org/obo/go/go-base.owl -o $@.tmp.owl && \ + $(ROBOT) remove -i $@.tmp.owl --base-iri http://purl.obolibrary.org/obo/GO_ --base-iri http://purl.obolibrary.org/obo/GOREL_ --base-iri http://purl.obolibrary.org/obo/GOCHE_ --axioms external --preserve-structure false --trim false -o $@.tmp.owl &&\ + mv $@.tmp.owl $(TMPDIR)/$@.owl; fi ## ONTOLOGY: envo diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl index 44bebed8e7..fa2f60b947 100644 --- a/src/ontology/imports/merged_import.owl +++ b/src/ontology/imports/merged_import.owl @@ -7,8 +7,8 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-09-18") + +Annotation(owl:versionInfo "2023-10-24") Declaration(Class()) Declaration(Class()) @@ -833,7 +833,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1093,7 +1092,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1439,6 +1437,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1463,7 +1462,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1706,6 +1704,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2170,6 +2169,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2196,8 +2196,11 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2229,7 +2232,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3964,6 +3966,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5119,13 +5122,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5425,7 +5424,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5884,10 +5882,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6109,6 +6105,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -8102,6 +8099,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -9076,7 +9076,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10042,6 +10041,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10566,6 +10566,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10648,6 +10649,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11166,7 +11168,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11218,6 +11219,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11477,6 +11479,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11572,6 +11576,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11695,6 +11700,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11723,6 +11729,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11753,6 +11760,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -12082,6 +12090,8 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12104,7 +12114,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12119,8 +12128,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12164,9 +12171,7 @@ Declaration(AnnotationProperty() Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12190,7 +12195,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12207,7 +12211,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12219,7 +12222,7 @@ Declaration(AnnotationProperty(rdfs:label)) Declaration(AnnotationProperty(rdfs:seeAlso)) Declaration(AnnotationProperty(owl:deprecated)) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) ############################ @@ -12250,35 +12253,26 @@ AnnotationAssertion(rdfs:isDefinedBy "curator note"@en) AnnotationAssertion(rdfs:label "curator note") -# Annotation Property: (term tracker item) - -AnnotationAssertion( "IAO:0000233") -AnnotationAssertion( "external") -AnnotationAssertion( "term_tracker_item") -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "term_tracker_item") -AnnotationAssertion(rdfs:label "term tracker item") - # Annotation Property: (expand assertion to) AnnotationAssertion(rdfs:label "expand assertion to") # Annotation Property: (preferred_root) -AnnotationAssertion( "IAO:0000700") -AnnotationAssertion( "external") -AnnotationAssertion( "has_ontology_root_term") -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "has_ontology_root_term") -AnnotationAssertion(rdfs:label "has ontology root term") AnnotationAssertion(rdfs:label "preferred_root") # Annotation Property: (term replaced by) AnnotationAssertion(rdfs:label "term replaced by") +# Annotation Property: () + +SubAnnotationPropertyOf( ) + +# Annotation Property: () + +SubAnnotationPropertyOf( ) + # Annotation Property: (never in taxon) AnnotationAssertion( "tooth SubClassOf 'never in taxon' value 'Aves'") @@ -12433,10 +12427,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12465,14 +12455,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12641,18 +12623,10 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12757,7 +12731,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "BFO:0000050") -AnnotationAssertion( "external") AnnotationAssertion( "quality") AnnotationAssertion( "spatial") AnnotationAssertion( "part_of") @@ -12792,7 +12765,6 @@ A continuant cannot have an occurrent as part: use 'participates in'. An occurre AnnotationAssertion( "has_part"@en) AnnotationAssertion( ) AnnotationAssertion( "BFO:0000051") -AnnotationAssertion( "external") AnnotationAssertion( "quality") AnnotationAssertion( "spatial") AnnotationAssertion( "has_part") @@ -12815,12 +12787,9 @@ AnnotationAssertion( "preceded_by"@en) AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:preceded_by") AnnotationAssertion( "BFO:0000062") -AnnotationAssertion( "external") -AnnotationAssertion( "preceded_by") AnnotationAssertion( ) AnnotationAssertion( "preceded_by") AnnotationAssertion(rdfs:label "preceded by"@en) -AnnotationAssertion(rdfs:label "preceded by") SubObjectPropertyOf( ) InverseObjectProperties( ) TransitiveObjectProperty() @@ -12832,12 +12801,9 @@ ObjectPropertyRange( "precedes"@en) AnnotationAssertion( "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en) AnnotationAssertion( "BFO:0000063") -AnnotationAssertion( "external") -AnnotationAssertion( "precedes") AnnotationAssertion( ) AnnotationAssertion( "precedes") AnnotationAssertion(rdfs:label "precedes"@en) -AnnotationAssertion(rdfs:label "precedes") SubObjectPropertyOf( ) TransitiveObjectProperty() ObjectPropertyDomain( ) @@ -12851,8 +12817,6 @@ AnnotationAssertion( "unfolds in"@en) AnnotationAssertion( "unfolds_in"@en) AnnotationAssertion( "BFO:0000066") -AnnotationAssertion( "external") -AnnotationAssertion( "occurs_in") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -12860,7 +12824,6 @@ AnnotationAssertion( "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant") AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "occurs in"@en) -AnnotationAssertion(rdfs:label "occurs in") AnnotationAssertion(rdfs:seeAlso "https://wiki.geneontology.org/Occurs_in"^^xsd:anyURI) InverseObjectProperties( ) ObjectPropertyDomain( ) @@ -13270,7 +13233,7 @@ SubObjectPropertyOf( ) FunctionalObjectProperty() -# Object Property: (bearer of) +# Object Property: (has characteristic) AnnotationAssertion( "bearer of"@en) AnnotationAssertion( "this apple is bearer of this red color"@en) @@ -13281,12 +13244,8 @@ AnnotationAssertion( "is bearer of"@en) AnnotationAssertion( ) AnnotationAssertion( "RO:0000053") -AnnotationAssertion( "external") -AnnotationAssertion( "bearer_of") -AnnotationAssertion( "bearer_of") AnnotationAssertion( "has_characteristic") AnnotationAssertion(rdfs:label "has characteristic"@en) -AnnotationAssertion(rdfs:label "bearer of") InverseFunctionalObjectProperty() ObjectPropertyRange( ) @@ -13299,11 +13258,8 @@ AnnotationAssertion( "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en) AnnotationAssertion( "participates_in"@en) AnnotationAssertion( "RO:0000056") -AnnotationAssertion( "external") -AnnotationAssertion( "participates_in") AnnotationAssertion( "participates_in") AnnotationAssertion(rdfs:label "participates in"@en) -AnnotationAssertion(rdfs:label "participates in") InverseObjectProperties( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -13319,11 +13275,8 @@ AnnotationAssertion( "has_participant"@en) AnnotationAssertion( "http://www.obofoundry.org/ro/#OBO_REL:has_participant") AnnotationAssertion( "RO:0000057") -AnnotationAssertion( "external") -AnnotationAssertion( "has_participant") AnnotationAssertion( "has_participant") AnnotationAssertion(rdfs:label "has participant"@en) -AnnotationAssertion(rdfs:label "has participant") ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -13544,13 +13497,10 @@ has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000") AnnotationAssertion( ) AnnotationAssertion( "RO:0002007") -AnnotationAssertion( "external") -AnnotationAssertion( "bounding_layer_of") AnnotationAssertion( ) AnnotationAssertion( "bounding_layer_of") AnnotationAssertion(rdfs:comment "A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.") AnnotationAssertion(rdfs:label "bounding layer of"@en) -AnnotationAssertion(rdfs:label "bounding layer of") SubObjectPropertyOf( ) ObjectPropertyDomain( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectPropertyRange( ) @@ -13561,8 +13511,6 @@ AnnotationAssertion( ) AnnotationAssertion( "2017-05-24T09:30:46Z"^^xsd:dateTime) AnnotationAssertion( "RO:0002013") -AnnotationAssertion( "external") -AnnotationAssertion( "has_regulatory_component_activity") AnnotationAssertion( "has_regulatory_component_activity") AnnotationAssertion(rdfs:label "has regulatory component activity") SubObjectPropertyOf( ) @@ -13574,8 +13522,6 @@ AnnotationAssertion( ) AnnotationAssertion( "2017-05-24T09:31:01Z"^^xsd:dateTime) AnnotationAssertion( "RO:0002014") -AnnotationAssertion( "external") -AnnotationAssertion( "has_negative_regulatory_component_activity") AnnotationAssertion( "has_negative_regulatory_component_activity") AnnotationAssertion(rdfs:comment "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.") AnnotationAssertion(rdfs:label "has negative regulatory component activity") @@ -13712,12 +13658,9 @@ TransitiveObjectProperty() AnnotationAssertion( "David Osumi-Sutherland") AnnotationAssertion( "starts_at_end_of") AnnotationAssertion( "RO:0002087") -AnnotationAssertion( "external") -AnnotationAssertion( "immediately_preceded_by") AnnotationAssertion( "immediately_preceded_by") AnnotationAssertion(rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en) AnnotationAssertion(rdfs:label "immediately preceded by"@en) -AnnotationAssertion(rdfs:label "immediately preceded by") SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -13729,13 +13672,10 @@ AnnotationAssertion( "meets") AnnotationAssertion( ) AnnotationAssertion( "RO:0002090") -AnnotationAssertion( "external") -AnnotationAssertion( "immediately_precedes") AnnotationAssertion( ) AnnotationAssertion( "immediately_precedes") AnnotationAssertion(rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en) AnnotationAssertion(rdfs:label "immediately precedes"@en) -AnnotationAssertion(rdfs:label "immediately precedes") SubObjectPropertyOf( ) # Object Property: (has soma location) @@ -13833,7 +13773,6 @@ AnnotationAssertion(Annotation( "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002131") -AnnotationAssertion( "external") AnnotationAssertion( "spatial") AnnotationAssertion( "overlaps") AnnotationAssertion( ) @@ -14045,12 +13984,9 @@ AnnotationAssertion( "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."@en) AnnotationAssertion( ) AnnotationAssertion( "RO:0002180") -AnnotationAssertion( "external") -AnnotationAssertion( "has_component") AnnotationAssertion( ) AnnotationAssertion( "has_component") AnnotationAssertion(rdfs:label "has component"@en) -AnnotationAssertion(rdfs:label "has component") AnnotationAssertion(rdfs:seeAlso ) SubObjectPropertyOf( ) @@ -14144,14 +14080,11 @@ AnnotationAssertion( "regulates (processual)") AnnotationAssertion( "false"^^xsd:boolean) AnnotationAssertion( "RO:0002211") -AnnotationAssertion( "external") -AnnotationAssertion( "regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "regulates") AnnotationAssertion(rdfs:label "regulates"@en) -AnnotationAssertion(rdfs:label "regulates") AnnotationAssertion(rdfs:label "regulates (processual)") SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14167,14 +14100,11 @@ AnnotationAssertion( "negatively regulates (process to process)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002212") -AnnotationAssertion( "external") -AnnotationAssertion( "negatively_regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "negatively_regulates") AnnotationAssertion(rdfs:label "negatively regulates"@en) -AnnotationAssertion(rdfs:label "negatively regulates") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14187,14 +14117,11 @@ AnnotationAssertion( "positively regulates (process to process)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002213") -AnnotationAssertion( "external") -AnnotationAssertion( "positively_regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "positively_regulates") AnnotationAssertion(rdfs:label "positively regulates"@en) -AnnotationAssertion(rdfs:label "positively regulates") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14211,12 +14138,9 @@ AnnotationAssertion( ) AnnotationAssertion( "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\".") AnnotationAssertion( "RO:0002215") -AnnotationAssertion( "external") -AnnotationAssertion( "capable_of") AnnotationAssertion( ) AnnotationAssertion( "capable_of") AnnotationAssertion(rdfs:label "capable of"@en) -AnnotationAssertion(rdfs:label "capable of") SubObjectPropertyOf( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -14227,11 +14151,8 @@ AnnotationAssertion( ) AnnotationAssertion( "has function in") AnnotationAssertion( "RO:0002216") -AnnotationAssertion( "external") -AnnotationAssertion( "capable_of_part_of") AnnotationAssertion( "capable_of_part_of") AnnotationAssertion(rdfs:label "capable of part of"@en) -AnnotationAssertion(rdfs:label "capable of part of") AnnotationAssertion(rdfs:seeAlso ) SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -14261,7 +14182,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002220") -AnnotationAssertion( "external") AnnotationAssertion( "spatial") AnnotationAssertion( "adjacent_to") AnnotationAssertion( ) @@ -14326,12 +14246,9 @@ AnnotationAssertion( "Chris Mungall") AnnotationAssertion( "started by") AnnotationAssertion( "RO:0002224") -AnnotationAssertion( "external") -AnnotationAssertion( "starts_with") AnnotationAssertion( ) AnnotationAssertion( "starts_with") AnnotationAssertion(rdfs:label "starts with"@en) -AnnotationAssertion(rdfs:label "starts with") SubObjectPropertyOf( ) SubObjectPropertyOf( ) TransitiveObjectProperty() @@ -14381,12 +14298,9 @@ AnnotationAssertion( "Chris Mungall") AnnotationAssertion( "finished by") AnnotationAssertion( "RO:0002230") -AnnotationAssertion( "external") -AnnotationAssertion( "ends_with") AnnotationAssertion( ) AnnotationAssertion( "ends_with") AnnotationAssertion(rdfs:label "ends with"@en) -AnnotationAssertion(rdfs:label "ends with") SubObjectPropertyOf( ) SubObjectPropertyOf( ) TransitiveObjectProperty() @@ -14398,12 +14312,9 @@ AnnotationAssertion( ) AnnotationAssertion( "starts with process that occurs in") AnnotationAssertion( "RO:0002231") -AnnotationAssertion( "external") -AnnotationAssertion( "has_start_location") AnnotationAssertion( ) AnnotationAssertion( "has_start_location") AnnotationAssertion(rdfs:label "has start location"@en) -AnnotationAssertion(rdfs:label "has start location") SubObjectPropertyOf( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -14415,12 +14326,9 @@ AnnotationAssertion( ) AnnotationAssertion( "ends with process that occurs in") AnnotationAssertion( "RO:0002232") -AnnotationAssertion( "external") -AnnotationAssertion( "has_end_location") AnnotationAssertion( ) AnnotationAssertion( "has_end_location") AnnotationAssertion(rdfs:label "has end location"@en) -AnnotationAssertion(rdfs:label "has end location") SubObjectPropertyOf( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -14432,15 +14340,12 @@ AnnotationAssertion( ) AnnotationAssertion( "consumes") AnnotationAssertion( "RO:0002233") -AnnotationAssertion( "external") -AnnotationAssertion( "has_input") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_input") AnnotationAssertion(rdfs:label "has input"@en) -AnnotationAssertion(rdfs:label "has input") AnnotationAssertion(rdfs:seeAlso "https://wiki.geneontology.org/Has_input"^^xsd:anyURI) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14453,15 +14358,12 @@ AnnotationAssertion( ) AnnotationAssertion( "produces") AnnotationAssertion( "RO:0002234") -AnnotationAssertion( "external") -AnnotationAssertion( "has_output") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_output") AnnotationAssertion(rdfs:label "has output"@en) -AnnotationAssertion(rdfs:label "has output") AnnotationAssertion(rdfs:seeAlso "https://wiki.geneontology.org/Has_output"^^xsd:anyURI) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14634,11 +14536,8 @@ AnnotationAssertion( "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002295") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_developmental_progression_of") AnnotationAssertion( "results_in_developmental_progression_of") AnnotationAssertion(rdfs:label "results in developmental progression of"@en) -AnnotationAssertion(rdfs:label "results in developmental progression of") AnnotationAssertion(rdfs:seeAlso ) SubObjectPropertyOf( ) ObjectPropertyDomain( ) @@ -14652,14 +14551,11 @@ AnnotationAssertion( ) AnnotationAssertion( "http://www.geneontology.org/GO.doc.development.shtml"^^xsd:anyURI) AnnotationAssertion( "RO:0002296") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_development_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_development_of") AnnotationAssertion(rdfs:label "results in development of"@en) -AnnotationAssertion(rdfs:label "results in development of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -14671,14 +14567,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002297") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_formation_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_formation_of") AnnotationAssertion(rdfs:label "results in formation of"@en) -AnnotationAssertion(rdfs:label "results in formation of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -14692,14 +14585,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002298") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_morphogenesis_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_morphogenesis_of") AnnotationAssertion(rdfs:label "results in morphogenesis of"@en) -AnnotationAssertion(rdfs:label "results in morphogenesis of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -14712,14 +14602,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002299") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_maturation_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_maturation_of") AnnotationAssertion(rdfs:label "results in maturation of"@en) -AnnotationAssertion(rdfs:label "results in maturation of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -14729,8 +14616,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002304") -AnnotationAssertion( "external") -AnnotationAssertion( "causally_upstream_of,_positive_effect") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "causally_upstream_of,_positive_effect") @@ -14746,8 +14631,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002305") -AnnotationAssertion( "external") -AnnotationAssertion( "causally_upstream_of,_negative_effect") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "causally_upstream_of,_negative_effect") @@ -14777,14 +14660,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002315") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_acquisition_of_features_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_acquisition_of_features_of") AnnotationAssertion(rdfs:label "results in acquisition of features of"@en) -AnnotationAssertion(rdfs:label "results in acquisition of features of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) ObjectPropertyRange( ) @@ -14909,11 +14789,8 @@ AnnotationAssertion( ) AnnotationAssertion( "regulates levels of (process to entity)") AnnotationAssertion( "RO:0002332") -AnnotationAssertion( "external") -AnnotationAssertion( "regulates_levels_of") AnnotationAssertion( "regulates_levels_of") AnnotationAssertion(rdfs:label "regulates levels of"@en) -AnnotationAssertion(rdfs:label "regulates levels of") SubObjectPropertyOf( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -14936,12 +14813,9 @@ AnnotationAssertion( ) AnnotationAssertion( "regulated by (processual)") AnnotationAssertion( "RO:0002334") -AnnotationAssertion( "external") -AnnotationAssertion( "regulated_by") AnnotationAssertion( ) AnnotationAssertion( "regulated_by") AnnotationAssertion(rdfs:label "regulated by"@en) -AnnotationAssertion(rdfs:label "regulated by") SubObjectPropertyOf( ) TransitiveObjectProperty() ObjectPropertyDomain( ) @@ -14952,12 +14826,9 @@ ObjectPropertyRange( "inverse of negatively regulates") AnnotationAssertion( ) AnnotationAssertion( "RO:0002335") -AnnotationAssertion( "external") -AnnotationAssertion( "negatively_regulated_by") AnnotationAssertion( ) AnnotationAssertion( "negatively_regulated_by") AnnotationAssertion(rdfs:label "negatively regulated by"@en) -AnnotationAssertion(rdfs:label "negatively regulated by") SubObjectPropertyOf( ) # Object Property: (positively regulated by) @@ -14965,12 +14836,9 @@ SubObjectPropertyOf( "inverse of positively regulates") AnnotationAssertion( ) AnnotationAssertion( "RO:0002336") -AnnotationAssertion( "external") -AnnotationAssertion( "positively_regulated_by") AnnotationAssertion( ) AnnotationAssertion( "positively_regulated_by") AnnotationAssertion(rdfs:label "positively regulated by"@en) -AnnotationAssertion(rdfs:label "positively regulated by") SubObjectPropertyOf( ) # Object Property: (related via localization to) @@ -14989,14 +14857,11 @@ ObjectPropertyRange( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002338") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_start_location") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_target_start_location") AnnotationAssertion(rdfs:label "has target start location"@en) -AnnotationAssertion(rdfs:label "has target start location") SubObjectPropertyOf( ) # Object Property: (has target end location) @@ -15004,14 +14869,11 @@ SubObjectPropertyOf( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002339") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_end_location") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_target_end_location") AnnotationAssertion(rdfs:label "has target end location"@en) -AnnotationAssertion(rdfs:label "has target end location") SubObjectPropertyOf( ) # Object Property: (results in transport along) @@ -15019,11 +14881,8 @@ SubObjectPropertyOf( "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l ") AnnotationAssertion( ) AnnotationAssertion( "RO:0002341") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_along") AnnotationAssertion( "results_in_transport_along") AnnotationAssertion(rdfs:label "results in transport along"@en) -AnnotationAssertion(rdfs:label "results in transport along") SubObjectPropertyOf( ) # Object Property: (results in transport across) @@ -15031,12 +14890,9 @@ SubObjectPropertyOf( "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002342") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_across") AnnotationAssertion( ) AnnotationAssertion( "results_in_transport_across") AnnotationAssertion(rdfs:label "results in transport across"@en) -AnnotationAssertion(rdfs:label "results in transport across") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -15045,11 +14901,8 @@ SubObjectPropertyOf( "'pollen tube growth' results_in growth_of some 'pollen tube'") AnnotationAssertion( ) AnnotationAssertion( "RO:0002343") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_growth_of") AnnotationAssertion( "results_in_growth_of") AnnotationAssertion(rdfs:label "results in growth of"@en) -AnnotationAssertion(rdfs:label "results in growth of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -15058,11 +14911,8 @@ SubObjectPropertyOf( "'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002344") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_to_from_or_in") AnnotationAssertion( "results_in_transport_to_from_or_in") AnnotationAssertion(rdfs:label "results in transport to from or in"@en) -AnnotationAssertion(rdfs:label "results in transport to from or in") SubObjectPropertyOf( ) # Object Property: (member of) @@ -15107,13 +14957,10 @@ SubObjectPropertyOf( "inverse of has output") AnnotationAssertion( ) AnnotationAssertion( "RO:0002353") -AnnotationAssertion( "external") -AnnotationAssertion( "output_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "output_of") AnnotationAssertion(rdfs:label "output of"@en) -AnnotationAssertion(rdfs:label "output of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -15302,11 +15149,8 @@ AnnotationAssertion( "inverse of upstream of") AnnotationAssertion( ) AnnotationAssertion( "RO:0002404") -AnnotationAssertion( "external") -AnnotationAssertion( "causally_downstream_of") AnnotationAssertion( "causally_downstream_of") AnnotationAssertion(rdfs:label "causally downstream of"@en) -AnnotationAssertion(rdfs:label "causally downstream of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -15316,11 +15160,8 @@ InverseObjectProperties( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002405") -AnnotationAssertion( "external") -AnnotationAssertion( "immediately_causally_downstream_of") AnnotationAssertion( "immediately_causally_downstream_of") AnnotationAssertion(rdfs:label "immediately causally downstream of"@en) -AnnotationAssertion(rdfs:label "immediately causally downstream of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -15382,13 +15223,10 @@ AnnotationAssertion(rdfs:label "caus AnnotationAssertion( "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002411") -AnnotationAssertion( "external") -AnnotationAssertion( "causally_upstream_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "causally_upstream_of") AnnotationAssertion(rdfs:label "causally upstream of"@en) -AnnotationAssertion(rdfs:label "causally upstream of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) TransitiveObjectProperty() @@ -15399,11 +15237,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002412") -AnnotationAssertion( "external") -AnnotationAssertion( "immediately_causally_upstream_of") AnnotationAssertion( "immediately_causally_upstream_of") AnnotationAssertion(rdfs:label "immediately causally upstream of"@en) -AnnotationAssertion(rdfs:label "immediately causally upstream of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -15414,9 +15249,7 @@ AnnotationAssertion( ) AnnotationAssertion( "influences (processual)") AnnotationAssertion( "RO:0002418") -AnnotationAssertion( "external") AnnotationAssertion( "affects") -AnnotationAssertion( "causally_upstream_of_or_within") AnnotationAssertion( "causally_upstream_of_or_within") AnnotationAssertion(rdfs:label "causally upstream of or within") SubObjectPropertyOf( ) @@ -15429,8 +15262,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "RO:0002427") -AnnotationAssertion( "external") -AnnotationAssertion( "causally_downstream_of_or_within") AnnotationAssertion( ) AnnotationAssertion( "causally_downstream_of_or_within") AnnotationAssertion(rdfs:label "causally downstream of or within") @@ -15893,8 +15724,6 @@ AnnotationAssertion( ) AnnotationAssertion( "") AnnotationAssertion( "RO:0002565") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_movement_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -16008,8 +15837,6 @@ AnnotationAssertion( "directly regulates (processual)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002578") -AnnotationAssertion( "external") -AnnotationAssertion( "directly_regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -16040,8 +15867,6 @@ SubObjectPropertyOf( (results in assembly of) AnnotationAssertion( "RO:0002588") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_assembly_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -16053,8 +15878,6 @@ SubObjectPropertyOf( (results in disassembly of) AnnotationAssertion( "RO:0002590") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_disassembly_of") AnnotationAssertion( "results_in_disassembly_of") AnnotationAssertion(rdfs:label "results in disassembly of") SubObjectPropertyOf( ) @@ -16064,11 +15887,8 @@ SubObjectPropertyOf( "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c") AnnotationAssertion( "RO:0002592") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_organization_of") AnnotationAssertion( "results_in_organization_of") AnnotationAssertion(rdfs:label "results in organization of") -SubObjectPropertyOf( ) SubObjectPropertyOf( ) # Object Property: (causal relation between material entity and a process) @@ -16118,8 +15938,6 @@ SubObjectPropertyOf( "Inverse of 'causal agent in process'") AnnotationAssertion( ) AnnotationAssertion( "RO:0002608") -AnnotationAssertion( "external") -AnnotationAssertion( "process_has_causal_agent") AnnotationAssertion( "process_has_causal_agent") AnnotationAssertion(rdfs:label "process has causal agent") SubObjectPropertyOf( ) @@ -16131,8 +15949,6 @@ AnnotationAssertion( "directly positively regulates (process to process)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002629") -AnnotationAssertion( "external") -AnnotationAssertion( "directly_positively_regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -16149,8 +15965,6 @@ AnnotationAssertion( "directly negatively regulates (process to process)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002630") -AnnotationAssertion( "external") -AnnotationAssertion( "directly_negatively_regulates") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -16166,13 +15980,10 @@ AnnotationAssertion( "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.") AnnotationAssertion( ) AnnotationAssertion( "RO:0003000") -AnnotationAssertion( "external") -AnnotationAssertion( "produces") AnnotationAssertion( ) AnnotationAssertion( "produces") AnnotationAssertion(rdfs:comment "Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.") AnnotationAssertion(rdfs:label "produces"@en) -AnnotationAssertion(rdfs:label "produces") InverseObjectProperties( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -16183,12 +15994,9 @@ AnnotationAssertion( "a produced_by b iff some process that occurs_in b has_output a.") AnnotationAssertion( ) AnnotationAssertion( "RO:0003001") -AnnotationAssertion( "external") -AnnotationAssertion( "produced_by") AnnotationAssertion( ) AnnotationAssertion( "produced_by") AnnotationAssertion(rdfs:label "produced by"@en) -AnnotationAssertion(rdfs:label "produced by") ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -16198,8 +16006,6 @@ AnnotationAssertion( ) AnnotationAssertion( "2018-12-13T11:26:17Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004007") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input_or_output") AnnotationAssertion( ) AnnotationAssertion( "has_primary_input_or_output") AnnotationAssertion(rdfs:label "has primary input or output") @@ -16211,8 +16017,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2018-12-13T11:26:32Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004008") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_output") AnnotationAssertion( ) AnnotationAssertion( "has_primary_output") AnnotationAssertion(rdfs:label "has primary output") @@ -16225,8 +16029,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2018-12-13T11:26:56Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004009") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input") AnnotationAssertion( ) AnnotationAssertion( "has_primary_input") AnnotationAssertion(rdfs:label "has primary input") @@ -16334,14 +16136,11 @@ AnnotationAssertion( ) AnnotationAssertion( "2020-06-08T17:21:33Z"^^xsd:dateTime) AnnotationAssertion( "RO:0012003") -AnnotationAssertion( "external") -AnnotationAssertion( "acts_on_population_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "acts_on_population_of") AnnotationAssertion(rdfs:label "acts on population of"@en) -AnnotationAssertion(rdfs:label "acts on population of") SubObjectPropertyOf( ) # Object Property: (results in fusion of) @@ -16349,14 +16148,11 @@ SubObjectPropertyOf( ) AnnotationAssertion( "2021-02-26T07:28:29Z"^^xsd:dateTime) AnnotationAssertion( "RO:0012008") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_fusion_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_fusion_of") AnnotationAssertion(rdfs:label "results in fusion of"@en) -AnnotationAssertion(rdfs:label "results in fusion of") SubObjectPropertyOf( ) # Object Property: (indirectly causally upstream of) @@ -16462,8 +16258,6 @@ AnnotationAssertion(rdfs:label "devi AnnotationAssertion( "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.") AnnotationAssertion( ) AnnotationAssertion( "RO:0019000") -AnnotationAssertion( "gene_ontology") -AnnotationAssertion( "regulates_characteristic") AnnotationAssertion( "regulates_characteristic") AnnotationAssertion(rdfs:label "regulates characteristic") SubObjectPropertyOf( ) @@ -16475,8 +16269,6 @@ ObjectPropertyRange( "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.") AnnotationAssertion( ) AnnotationAssertion( "RO:0019001") -AnnotationAssertion( "gene_ontology") -AnnotationAssertion( "positively_regulates_characteristic") AnnotationAssertion( "positively_regulates_characteristic") AnnotationAssertion(rdfs:label "positively regulates characteristic") SubObjectPropertyOf( ) @@ -16486,8 +16278,6 @@ SubObjectPropertyOf( "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.") AnnotationAssertion( ) AnnotationAssertion( "RO:0019002") -AnnotationAssertion( "gene_ontology") -AnnotationAssertion( "negatively_regulates_characteristic") AnnotationAssertion( "negatively_regulates_characteristic") AnnotationAssertion(rdfs:label "negatively regulates characteristic") SubObjectPropertyOf( ) @@ -16498,8 +16288,6 @@ AnnotationAssertion( ) AnnotationAssertion( "2018-09-26T01:08:58Z"^^xsd:dateTime) AnnotationAssertion( "RO:0040036") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_changes_to_anatomical_or_cellular_structure") AnnotationAssertion( "results_in_changes_to_anatomical_or_cellular_structure") AnnotationAssertion(rdfs:label "results in changes to anatomical or cellular structure") SubObjectPropertyOf( ) @@ -16734,7 +16522,6 @@ AnnotationAssertion(Annotation( ) "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] ") AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "role"@en) -EquivalentClasses( ) SubClassOf( ) # Class: (generically dependent continuant) @@ -20636,7 +20423,6 @@ AnnotationAssertion( "CHEBI:24431") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "chemical entity") -SubClassOf( ) # Class: (biological role) @@ -26041,7 +25827,6 @@ AnnotationAssertion( "CHEBI:36080") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein") -EquivalentClasses( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -30686,16 +30471,6 @@ DisjointClasses( ) DisjointClasses( ) -# Class: (native cell) - -AnnotationAssertion(Annotation( "CARO:mah") "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).") -AnnotationAssertion( "CARO:0000013") -AnnotationAssertion( "cell in vivo") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12).") -AnnotationAssertion(rdfs:label "native cell") -SubClassOf( ) - # Class: (fibroblast neural crest derived) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "Any fibroblast that is deriived from the neural crest.") @@ -30737,7 +30512,6 @@ AnnotationAssertion( "germ line stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (male germ cell) @@ -30762,8 +30536,6 @@ AnnotationAssertion( "WBbt:0006799") AnnotationAssertion(rdfs:label "spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (spermatid) @@ -30778,8 +30550,6 @@ AnnotationAssertion( "nematoblast") AnnotationAssertion(rdfs:label "spermatid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (sperm) @@ -30796,7 +30566,6 @@ AnnotationAssertion( "spermatozoon") AnnotationAssertion(rdfs:label "sperm") SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (spermatogonium) @@ -30811,7 +30580,6 @@ AnnotationAssertion( "spermatogonial cell") AnnotationAssertion(rdfs:label "spermatogonium") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (female germ cell) @@ -30854,7 +30622,6 @@ AnnotationAssertion( "oogonial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (egg cell) @@ -30870,8 +30637,7 @@ AnnotationAssertion( "mature oocyte") AnnotationAssertion( "ovum") AnnotationAssertion(rdfs:label "egg cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) -SubClassOf( ) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -30896,7 +30662,6 @@ SubClassOf( ObjectSomeValuesFrom( "glioblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (neuroblast (sensu Vertebrata)) @@ -30920,8 +30685,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.") AnnotationAssertion(rdfs:label "stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -30932,7 +30696,7 @@ AnnotationAssertion( "unipotent stem cell") AnnotationAssertion( "unipotential stem cell") AnnotationAssertion(rdfs:label "single fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (epithelial fate stem cell) @@ -30955,7 +30719,7 @@ AnnotationAssertion( "VHOG:0001485") AnnotationAssertion( "blood forming stem cell") AnnotationAssertion( "hemopoietic stem cell") -AnnotationAssertion(Annotation( ) "HSC") +AnnotationAssertion(Annotation( ) "HSC") AnnotationAssertion( "colony forming unit hematopoietic") AnnotationAssertion( ) AnnotationAssertion( ) @@ -30970,8 +30734,8 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:add") Annotation( "ISBN:0721601464") "A progenitor cell committed to the erythroid lineage.") AnnotationAssertion( "BTO:0004911") -AnnotationAssertion(Annotation( ) "BFU-E") -AnnotationAssertion(Annotation( ) "CFU-E") +AnnotationAssertion(Annotation( ) "BFU-E") +AnnotationAssertion(Annotation( ) "CFU-E") AnnotationAssertion( "blast forming unit erythroid") AnnotationAssertion( "burst forming unit erythroid") AnnotationAssertion( "colony forming unit erythroid") @@ -30989,16 +30753,15 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally this term had some plant germ line cell children.") AnnotationAssertion(rdfs:label "germ line cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) # Class: (monoblast) AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:1104740") Annotation( "http://en.wikipedia.org/wiki/Monoblast") Annotation( "http://www.copewithcytokines.de") "A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus.") AnnotationAssertion( "CALOHA:TS-1195") AnnotationAssertion( "FMA:83553") -AnnotationAssertion(Annotation( ) "CFU-M") +AnnotationAssertion(Annotation( ) "CFU-M") AnnotationAssertion( "colony forming unit macrophage") AnnotationAssertion( "colony forming unit monocyte") AnnotationAssertion( "monocyte stem cell") @@ -31017,7 +30780,7 @@ AnnotationAssertion( "multipotent cell") AnnotationAssertion( "multipotent stem cell") AnnotationAssertion(rdfs:label "multi fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (common myeloid progenitor) @@ -31025,9 +30788,9 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "BTO:0004730") AnnotationAssertion( "common myeloid precursor") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") AnnotationAssertion(Annotation( "ISBN:0878932437") "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte") AnnotationAssertion(Annotation( "ISBN:0878932437") "multipotential myeloid stem cell") AnnotationAssertion(Annotation( "ISBN:0878932437") "myeloid stem cell") @@ -31067,8 +30830,8 @@ AnnotationAssertion( "common lymphocyte precursor") AnnotationAssertion( "common lymphocyte progenitor") AnnotationAssertion( "common lymphoid precursor") -AnnotationAssertion(Annotation( ) "CLP") -AnnotationAssertion(Annotation( ) "ELP") +AnnotationAssertion(Annotation( ) "CLP") +AnnotationAssertion(Annotation( ) "ELP") AnnotationAssertion( "committed lymphopoietic stem cell") AnnotationAssertion( "early lymphocyte progenitor") AnnotationAssertion( "lymphoid stem cell") @@ -31096,7 +30859,7 @@ AnnotationAssertion( "blast cell") AnnotationAssertion(rdfs:comment "define using PATO mulit-potent or oligopotent?") AnnotationAssertion(rdfs:label "non-terminally differentiated cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (myoblast) @@ -31108,7 +30871,6 @@ AnnotationAssertion( "FMA:70335") AnnotationAssertion( "VHOG:0001529") AnnotationAssertion(rdfs:label "myoblast") -SubClassOf( ) SubClassOf( ) # Class: (fibroblast) @@ -31191,7 +30953,7 @@ AnnotationAssertion(Annotation( "VHOG:0001532") AnnotationAssertion( "XAO:0000031") AnnotationAssertion(rdfs:label "ciliated cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (ependymal cell) @@ -31219,8 +30981,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI) -SubClassOf( ) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -31237,7 +30999,6 @@ AnnotationAssertion(Annotation( "duct epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (branched duct epithelial cell) @@ -31254,7 +31015,6 @@ AnnotationAssertion(rdfs:label "bloo EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (non-branched duct epithelial cell) @@ -31270,7 +31030,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (squamous epithelial cell) @@ -31294,14 +31053,13 @@ SubClassOf( ObjectSomeValuesFrom( "stratified epithelial cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (circulating cell) AnnotationAssertion(Annotation( "GOC:add") "A cell which moves among different tissues of the body, via blood, lymph, or other medium.") AnnotationAssertion(rdfs:label "circulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (blood cell) @@ -31316,10 +31074,8 @@ SubClassOf(Annotation( # Class: (epithelial cell of lung) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "An epithelial cell of the lung.") -AnnotationAssertion( ) AnnotationAssertion( "BTO:0004299") AnnotationAssertion( "lung epithelial cell") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of lung") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) @@ -31332,8 +31088,6 @@ AnnotationAssertion( "pancreatic epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of pancreas") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (T cell) @@ -31403,9 +31157,7 @@ AnnotationAssertion( "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).") AnnotationAssertion(rdfs:label "sensory epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -SubClassOf( ) # Class: (interneuron) @@ -31568,6 +31320,7 @@ SubClassOf( ObjectSomeValuesFrom( (glial cell) AnnotationAssertion(Annotation( "MESH:D009457") "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.") +AnnotationAssertion( ) AnnotationAssertion( "BTO:0002606") AnnotationAssertion( "CALOHA:TS-0415") AnnotationAssertion( "FBbt:00005144") @@ -31575,6 +31328,7 @@ AnnotationAssertion( "neuroglial cell") AnnotationAssertion( "neuroglia") AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571") AnnotationAssertion(rdfs:label "glial cell") SubClassOf( ) @@ -31586,7 +31340,7 @@ AnnotationAssertion( "CALOHA:TS-2027") AnnotationAssertion( "FMA:54538") AnnotationAssertion( "macrogliocyte") -AnnotationAssertion(Annotation( "doi:10.1152/physrev.2001.81.2.871") Annotation( ) "macroglia") +AnnotationAssertion(Annotation( "doi:10.1152/physrev.2001.81.2.871") Annotation( ) "macroglia") AnnotationAssertion(rdfs:label "macroglial cell") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -31637,15 +31391,15 @@ AnnotationAssertion( "bone marrow stromal cells") AnnotationAssertion( "colony-forming unit-fibroblast") AnnotationAssertion(Annotation( "PMID:11378515") "marrow stromal cells") -AnnotationAssertion(Annotation( ) "BMSC") -AnnotationAssertion(Annotation( ) "CFU-F") -AnnotationAssertion(Annotation( "PMID:11378515") Annotation( ) "MSC") +AnnotationAssertion(Annotation( ) "BMSC") +AnnotationAssertion(Annotation( ) "CFU-F") +AnnotationAssertion(Annotation( "PMID:11378515") Annotation( ) "MSC") AnnotationAssertion( "mesenchymal precursor cell") -AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "mesenchymal progenitor cells") +AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "mesenchymal progenitor cells") AnnotationAssertion( "mesenchymal stem cell") AnnotationAssertion( "mesenchymal stromal cell") -AnnotationAssertion(Annotation( ) "mesenchymal stromal cells") -AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "stem cells, mesenchymal") +AnnotationAssertion(Annotation( ) "mesenchymal stromal cells") +AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "stem cells, mesenchymal") AnnotationAssertion(rdfs:comment "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.") AnnotationAssertion(rdfs:label "mesenchymal stem cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/474") @@ -31709,7 +31463,7 @@ SubClassOf( ObjectSomeValuesFrom( (professional antigen presenting cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.") -AnnotationAssertion(Annotation( ) "APC") +AnnotationAssertion(Annotation( ) "APC") AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.") AnnotationAssertion(rdfs:label "professional antigen presenting cell") @@ -31746,16 +31500,12 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) # Class: (visual pigment cell) AnnotationAssertion( "pigment cell") AnnotationAssertion(rdfs:label "visual pigment cell") SubClassOf( ) -SubClassOf( ) # Class: (glandular epithelial cell) @@ -31765,18 +31515,15 @@ AnnotationAssertion( "glandular epithelial cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (secretory cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell that specializes in controlled release of one or more substances.") -AnnotationAssertion( ) AnnotationAssertion( "BTO:0003659") AnnotationAssertion( "FMA:86916") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "secretory cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (exocrine cell) @@ -31786,7 +31533,6 @@ AnnotationAssertion( "exocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (glycosaminoglycan secreting cell) @@ -31874,8 +31620,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (enteroendocrine cell) @@ -32016,6 +31761,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "BTO:0003939") AnnotationAssertion( "FMA:18688") +AnnotationAssertion(Annotation( "PMID:16790079") "corpus luteum cell") AnnotationAssertion( "lutein cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "luteal cell") @@ -32042,7 +31788,6 @@ AnnotationAssertion( "Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated") AnnotationAssertion(rdfs:label "Leydig cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -32063,7 +31808,6 @@ AnnotationAssertion(rdfs:comment "He AnnotationAssertion(rdfs:label "hepatocyte") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -32074,7 +31818,7 @@ SubClassOf( ObjectSomeValuesFrom( "FB:ma") "A cell whose primary function is to shorten.") AnnotationAssertion(rdfs:label "contractile cell") -SubClassOf( ) +SubClassOf( ) # Class: (myoepithelial cell) @@ -32087,7 +31831,6 @@ AnnotationAssertion( "myoepithelial cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (muscle cell) @@ -32102,11 +31845,9 @@ AnnotationAssertion( "muscle fiber") AnnotationAssertion( "myocyte") AnnotationAssertion(rdfs:label "muscle cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Muscle_cells.svg"^^xsd:anyURI) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Muscle_cells.svg"^^xsd:anyURI) SubClassOf( ) SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (cell of skeletal muscle) @@ -32120,8 +31861,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell of skeletal muscle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (slow muscle cell) @@ -32165,7 +31905,6 @@ AnnotationAssertion( "receptor cell") AnnotationAssertion(rdfs:label "sensory receptor cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pain receptor cell) @@ -32235,7 +31974,7 @@ AnnotationAssertion( "CALOHA:TS-0868") AnnotationAssertion( "FMA:86740") AnnotationAssertion(rdfs:label "photoreceptor cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -32243,7 +31982,7 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "FB:ma") "A cell whose function is determined by the generation or the reception of an electric signal.") AnnotationAssertion(rdfs:label "electrically active cell") -SubClassOf( ) +SubClassOf( ) # Class: (lining cell) @@ -32266,7 +32005,7 @@ SubClassOf( ObjectSomeValuesFrom( "JB:jb") "A cell whose primary function is to prevent the transport of stuff across compartments.") AnnotationAssertion(rdfs:label "barrier cell") -SubClassOf( ) +SubClassOf( ) # Class: (Sertoli cell) @@ -32305,7 +32044,7 @@ SubClassOf( ObjectSomeValuesFrom( "FB:ma") "A cell that moves by its own activities.") AnnotationAssertion(rdfs:label "motile cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (ectodermal cell) @@ -32341,19 +32080,19 @@ AnnotationAssertion(Annotation( "FMA:68647") AnnotationAssertion( "non-nucleated cell") AnnotationAssertion(rdfs:label "anucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) DisjointClasses( ) # Class: (single nucleate cell) AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell with a single nucleus.") AnnotationAssertion(rdfs:label "single nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (binucleate cell) AnnotationAssertion(rdfs:label "binucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (multinucleate cell) @@ -32364,7 +32103,7 @@ AnnotationAssertion( "syncytial cell") AnnotationAssertion( "syncytium") AnnotationAssertion(rdfs:label "multinucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (erythrocyte) @@ -32411,11 +32150,10 @@ AnnotationAssertion( "FMA:83806") AnnotationAssertion( "MESH:D010586") AnnotationAssertion(rdfs:label "phagocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -SubClassOf( ) # Class: (macrophage) @@ -32497,18 +32235,17 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "transitional epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (eukaryotic cell) AnnotationAssertion( "MESH:D005057") AnnotationAssertion(rdfs:label "eukaryotic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Eumycetozoan cell) AnnotationAssertion(rdfs:label "Eumycetozoan cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (eye photoreceptor cell) @@ -32524,7 +32261,7 @@ SubClassOf( "TAIR:sr") "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.") AnnotationAssertion(rdfs:label "structural cell") -SubClassOf( ) +SubClassOf( ) # Class: (somatotropin secreting cell) @@ -32556,10 +32293,8 @@ SubClassOf( (tracheal epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell found in the trachea.") -AnnotationAssertion( ) AnnotationAssertion( "FMA:74793") AnnotationAssertion( "tracheocyte") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'") AnnotationAssertion(rdfs:label "tracheal epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -32640,7 +32375,7 @@ SubClassOf( ObjectSomeValuesFrom( "FB:ma") "A cell that is specialised to accumulate a particular substance(s).") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "stuff accumulating cell") -SubClassOf( ) +SubClassOf( ) # Class: (extracellular matrix secreting cell) @@ -32650,14 +32385,14 @@ SubClassOf( (oxygen accumulating cell) AnnotationAssertion(rdfs:label "oxygen accumulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (migratory neural crest cell) AnnotationAssertion(Annotation( "doi:10.1016/j.stem.2015.02.017") "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.") AnnotationAssertion( "FMA:86667") AnnotationAssertion(rdfs:label "migratory neural crest cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32666,7 +32401,6 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") Annotation( "PMID:5025404") "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.") AnnotationAssertion(rdfs:label "mesenchyme condensation cell") -SubClassOf( ) SubClassOf( ) # Class: (adrenal medulla chromaffin cell) @@ -32706,7 +32440,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "scleral cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (choroidal cell of the eye) @@ -32715,15 +32448,13 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "choroidal cell of the eye") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (extraembryonic cell) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extraembryonic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amnioserosal cell) @@ -32806,7 +32537,6 @@ AnnotationAssertion(Annotation( "epidermal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (animal zygote) @@ -32898,19 +32628,20 @@ AnnotationAssertion(rdfs:label "male EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (polyploid cell) -AnnotationAssertion(Annotation( "FB:ma") "A cell whose nucleus, or nuclei, each contain more than two haploid genomes.") +AnnotationAssertion(Annotation( "https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy"^^xsd:anyURI) Annotation( "FB:ma") Annotation( "PMID:32646579") "A cell that contains more than two haploid sets of chromosomes.") AnnotationAssertion(rdfs:label "polyploid cell") -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (haploid cell) AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell whose nucleus contains a single haploid genome.") +AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "haploid cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (endopolyploid cell) @@ -33002,7 +32733,6 @@ AnnotationAssertion(Annotation( "CALOHA:TS-1119") AnnotationAssertion( "FMA:83434") AnnotationAssertion( "white adipose cell") -AnnotationAssertion( "white fat cell") AnnotationAssertion( "white adipocyte") AnnotationAssertion(rdfs:label "white fat cell") SubClassOf( ) @@ -33112,7 +32842,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "JB:jb") "A cell whose primary function is to protect the organism.") AnnotationAssertion(rdfs:label "defensive cell") -SubClassOf( ) +SubClassOf( ) # Class: (follicle cell of egg chamber) @@ -33164,7 +32894,6 @@ SubClassOf( ObjectSomeValuesFrom( "An epithelial somatic cell associated with a maturing oocyte.") AnnotationAssertion(rdfs:label "follicular epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (granulosa cell) @@ -33241,7 +32970,6 @@ SubClassOf( "GOC:tfm") Annotation( "ISBN:0198529171") "A paracrine cell is a secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it.") AnnotationAssertion(rdfs:label "paracrine cell") SubClassOf( ) -SubClassOf( ) # Class: (cardiac muscle myoblast) @@ -33261,8 +32989,6 @@ AnnotationAssertion(Annotation( "satellite cell") AnnotationAssertion(rdfs:label "smooth muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (skeletal muscle myoblast) @@ -33271,16 +32997,13 @@ AnnotationAssertion( "skeletal myoblast") AnnotationAssertion(rdfs:label "skeletal muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (fungal cell) AnnotationAssertion(rdfs:label "fungal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -DisjointClasses( ) # Class: (syncytiotrophoblast cell) @@ -33295,7 +33018,7 @@ AnnotationAssertion( "syncytiotrophoblast cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (afferent neuron) @@ -33329,7 +33052,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.") AnnotationAssertion(rdfs:label "neuron") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Neuron_cells.svg"^^xsd:anyURI) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Neuron_cells.svg"^^xsd:anyURI) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -33343,8 +33066,6 @@ AnnotationAssertion( "Derived from UBERON:0002342 neural crest.") AnnotationAssertion(rdfs:label "melanoblast") SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (lymphocyte) @@ -33376,17 +33097,6 @@ EquivalentClasses( ObjectIntersection SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (animal cell) - -AnnotationAssertion( "A native cell that is part of some Metazoa.") -AnnotationAssertion( "metazoan cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "animal cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Animal_cells.svg"^^xsd:anyURI) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (basophilic erythroblast) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721601464") "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.") @@ -33487,8 +33197,8 @@ AnnotationAssertion(Annotation( "ISBN:0721601464") Annotation( "PMCID:PMC2213186") Annotation( "PMCID:PMC548021") "granulocyte-macrophage progenitor") AnnotationAssertion( "granulocyte/monocyte precursor") AnnotationAssertion( "granulocyte/monocyte progenitor") -AnnotationAssertion(Annotation( "ISBN:0721601464") Annotation( "PMCID:PMC2213186") Annotation( "PMCID:PMC548021") Annotation( ) "CFU-GM") -AnnotationAssertion(Annotation( "ISBN:0721601464") Annotation( "PMCID:PMC2213186") Annotation( "PMCID:PMC548021") Annotation( ) "GMP") +AnnotationAssertion(Annotation( "ISBN:0721601464") Annotation( "PMCID:PMC2213186") Annotation( "PMCID:PMC548021") Annotation( ) "CFU-GM") +AnnotationAssertion(Annotation( "ISBN:0721601464") Annotation( "PMCID:PMC2213186") Annotation( "PMCID:PMC548021") Annotation( ) "GMP") AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.") AnnotationAssertion(rdfs:label "granulocyte monocyte progenitor cell") @@ -33528,8 +33238,8 @@ AnnotationAssertion( "BTO:0004044") AnnotationAssertion( "FMA:67766") AnnotationAssertion( "amacrine neuron") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "AC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "AC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amacrine cell") @@ -33551,10 +33261,8 @@ SubClassOf( ObjectSomeValuesFrom( (angioblastic mesenchymal cell) AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:12768659") "A mesenchymal stem cell capable of developing into blood vessel endothelium.") -AnnotationAssertion( ) AnnotationAssertion( "angioblast") AnnotationAssertion( "chondroplast") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.") AnnotationAssertion(rdfs:label "angioblastic mesenchymal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) @@ -33621,7 +33329,6 @@ AnnotationAssertion( "corneal epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (monocyte) @@ -33669,7 +33376,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") "An erythrocyte lacking a nucleus.") AnnotationAssertion( "red blood cell") -AnnotationAssertion(Annotation( ) "RBC") +AnnotationAssertion(Annotation( ) "RBC") AnnotationAssertion(rdfs:label "enucleate erythrocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -33684,7 +33391,6 @@ AnnotationAssertion( "NIFSTD:sao862606388") AnnotationAssertion( "projection neuron") AnnotationAssertion( "pyramidal cell") -AnnotationAssertion( "pyramidal neuron") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pyramidal neuron") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -33752,7 +33458,7 @@ SubClassOf( ObjectSomeValuesFrom( "TAIR:sr") "A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances.") AnnotationAssertion(rdfs:label "transporting cell") -SubClassOf( ) +SubClassOf( ) # Class: (supporting cell) @@ -33760,7 +33466,7 @@ AnnotationAssertion(Annotation( "BTO:0002315") AnnotationAssertion( "supportive cell") AnnotationAssertion(rdfs:label "supporting cell") -SubClassOf( ) +SubClassOf( ) # Class: (hepatic stellate cell) @@ -33824,13 +33530,12 @@ SubClassOf( ObjectSomeValuesFrom( "JB:jb") Annotation( "PMID:10495875") Annotation( "PMID:15961560") Annotation( "doi:10.23937/2572-407X.1510006") "An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions.") AnnotationAssertion(Annotation( "doi:10.23937/2572-407X.1510006") "folliculo-stellate cell") AnnotationAssertion(Annotation( "PMID:34734454") "pituitary folliculostellate cell") -AnnotationAssertion(Annotation( "PMID:34734454") Annotation( ) "FS cell") -AnnotationAssertion(Annotation( "doi:10.23937/2572-407X.1510006") Annotation( ) "FSC") +AnnotationAssertion(Annotation( "PMID:34734454") Annotation( ) "FS cell") +AnnotationAssertion(Annotation( "doi:10.23937/2572-407X.1510006") Annotation( ) "FSC") AnnotationAssertion(Annotation( "PMID:34734454") "Sox2-positive stem cell") AnnotationAssertion(Annotation( "PMID:18287078") Annotation( "PMID:31620083") Annotation( "PMID:34734454") Annotation( "doi:10.23937/2572-407X.1510006") rdfs:comment "Folliculostellate cells are a heterogeneous group of cells rather than a single cell type, with different morphology and gene expression profiles. Due to this heterogeneity, it is unclear if different properties that have been attributed to folliculostellate cells (pluripotent, proliferative, phagocytic) are common in all folliculostellate cells or limited to particular subsets.") AnnotationAssertion(rdfs:label "folliculostellate cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33943,8 +33648,6 @@ AnnotationAssertion( "FMA:72292") AnnotationAssertion(rdfs:label "primary spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (secondary spermatocyte) @@ -33955,8 +33658,6 @@ AnnotationAssertion( "FMA:72293") AnnotationAssertion(rdfs:label "secondary spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (fenestrated cell) @@ -33964,7 +33665,6 @@ SubClassOf( ObjectSomeValuesFrom( "window cell") AnnotationAssertion(rdfs:label "fenestrated cell") SubClassOf( ) -SubClassOf( ) # Class: (collagen secreting cell) @@ -34002,7 +33702,6 @@ AnnotationAssertion(rdfs:label "prim EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (female gamete) @@ -34028,8 +33727,6 @@ AnnotationAssertion(Annotation( "muscle precursor cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (radial glial cell) @@ -34082,10 +33779,12 @@ SubClassOf( (choroid plexus epithelial cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:9550134") "Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord.") +AnnotationAssertion( ) AnnotationAssertion( "2023-08-04T08:48:30Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "choroid plexus cell") AnnotationAssertion( "FMA:70549") AnnotationAssertion( "epithelial cell of choroid plexus") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "choroid plexus epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -34125,8 +33824,6 @@ AnnotationAssertion( "MESH:D053687") AnnotationAssertion(rdfs:label "somatic stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (urothelial cell) @@ -34135,7 +33832,6 @@ AnnotationAssertion( "urinary tract transitional epithelial cell") AnnotationAssertion(rdfs:label "urothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (striated muscle cell) @@ -34177,8 +33873,8 @@ AnnotationAssertion( "MESH:D012165") AnnotationAssertion( "gangliocyte") AnnotationAssertion( "ganglion cell of retina") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "RGC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "RGC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal ganglion cell") @@ -34191,8 +33887,8 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "BTO:0004120") AnnotationAssertion( "horizontal cell") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "HC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "HC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retina horizontal cell") @@ -34224,9 +33920,9 @@ SubClassOf( ObjectSomeValuesFrom( "PMID:14689473") "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.") AnnotationAssertion( ) -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "BC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") -AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "BC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") +AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal bipolar neuron") @@ -34292,8 +33988,6 @@ SubClassOf( ObjectSomeValuesFrom( (myeloid leukocyte) AnnotationAssertion(Annotation( "GOC:add") "A cell of the monocyte, granulocyte, or mast cell lineage.") -AnnotationAssertion( ) -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "myeloid leukocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -34372,13 +34066,11 @@ SubClassOf(Annotation( # Class: (myeloid dendritic cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:10449155") Annotation( "PMID:17332250") Annotation( "PMID:9521319") "A dendritic cell of the myeloid lineage.") -AnnotationAssertion( ) AnnotationAssertion( "interdigitating cell") AnnotationAssertion( "veiled cell") AnnotationAssertion( "BTO:0004721") AnnotationAssertion( "CD11c+CD123- DC") AnnotationAssertion( "mDC") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).") AnnotationAssertion(rdfs:label "myeloid dendritic cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) @@ -34742,14 +34434,12 @@ SubClassOf( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into slow muscle fibers.") AnnotationAssertion(rdfs:label "slow muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (fast muscle myoblast) AnnotationAssertion(Annotation( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into fast muscle fibers.") AnnotationAssertion(rdfs:label "fast muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (classical monocyte) @@ -34765,10 +34455,12 @@ SubClassOf(Annotation( # Class: (tissue-resident macrophage) AnnotationAssertion(Annotation( "GOC:ana") Annotation( "GO_REF:0000031") Annotation( "PMID:19770654") "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.") +AnnotationAssertion( ) AnnotationAssertion( "FMA:84642") AnnotationAssertion( "FMA:84644") AnnotationAssertion( "fixed macrophage") AnnotationAssertion( "resting histiocyte") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tissue-resident macrophage") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -34834,10 +34526,12 @@ SubClassOf( ObjectSomeValuesFrom( (early lymphoid progenitor) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:pam") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:19022770") "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative.") +AnnotationAssertion( ) AnnotationAssertion( "lymphoid-primed multipotent progenitor") -AnnotationAssertion(Annotation( ) "ELP") -AnnotationAssertion(Annotation( "PMID:18371378") Annotation( ) "GMLP") -AnnotationAssertion(Annotation( ) "LMPP") +AnnotationAssertion(Annotation( ) "ELP") +AnnotationAssertion(Annotation( "PMID:18371378") Annotation( ) "GMLP") +AnnotationAssertion(Annotation( ) "LMPP") +AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.") AnnotationAssertion(rdfs:label "early lymphoid progenitor") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) @@ -35142,8 +34836,7 @@ AnnotationAssertion( "haemopoietic cell") AnnotationAssertion( "hemopoietic cell") AnnotationAssertion(rdfs:label "hematopoietic cell") -SubClassOf( ) -SubClassOf( ) +SubClassOf( ) # Class: (conventional dendritic cell) @@ -35333,8 +35026,7 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bone cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (terminally differentiated osteoblast) @@ -35387,9 +35079,9 @@ SubClassOf( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0878932437") Annotation( "PMCID:PMC2212039") Annotation( "PMID:10724173") Annotation( "PMID:16551251") Annotation( "PMID:16647566") "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1.") AnnotationAssertion( "common myeloid precursor, CD34-positive") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") AnnotationAssertion(Annotation( "ISBN:0878932437") "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte") AnnotationAssertion(Annotation( "ISBN:0878932437") "multipotential myeloid stem cell") AnnotationAssertion(Annotation( "ISBN:0878932437") "myeloid stem cell") @@ -35414,8 +35106,8 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:add") Annotation( "ISBN:0721601464") "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).") AnnotationAssertion( "BTO:0004911") -AnnotationAssertion(Annotation( ) "BFU-E") -AnnotationAssertion(Annotation( ) "CFU-E") +AnnotationAssertion(Annotation( ) "BFU-E") +AnnotationAssertion(Annotation( ) "CFU-E") AnnotationAssertion( "blast forming unit erythroid") AnnotationAssertion( "burst forming unit erythroid") AnnotationAssertion( "colony forming unit erythroid") @@ -36014,7 +35706,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69075") AnnotationAssertion(rdfs:label "endo-epithelial cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (ecto-epithelial cell) @@ -36025,7 +35716,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69074") AnnotationAssertion(rdfs:label "ecto-epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (meso-epithelial cell) @@ -36036,7 +35726,6 @@ AnnotationAssertion( "epithelial mesenchymal cell") AnnotationAssertion(rdfs:label "meso-epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pancreatic ductal cell) @@ -36587,7 +36276,6 @@ AnnotationAssertion( "corneocyte") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -36766,7 +36454,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2010-08-30T02:00:42Z") AnnotationAssertion( "FMA:86577") -AnnotationAssertion(Annotation( "PMID:18442648") Annotation( ) "HpSC") +AnnotationAssertion(Annotation( "PMID:18442648") Annotation( ) "HpSC") AnnotationAssertion(rdfs:label "hepatic stem cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/800") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -36807,11 +36495,9 @@ EquivalentClasses( ObjectIntersection # Class: (epithelial cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the tracheobronchial tree.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-02T02:09:14Z") AnnotationAssertion( "FMA:66816") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of tracheobronchial tree") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -36915,7 +36601,6 @@ AnnotationAssertion( "vertebrate lens cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (lens epithelial cell) @@ -36998,13 +36683,11 @@ SubClassOf( (pulmonary interstitial fibroblast) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-07T02:29:38Z") AnnotationAssertion( "FMA:84467") AnnotationAssertion( "pulmonary myofibroblast") AnnotationAssertion( "pulmonary septal cell") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pulmonary interstitial fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -37016,7 +36699,7 @@ AnnotationAssertion( "2010-09-07T03:32:33Z") AnnotationAssertion( "FMA:67513") AnnotationAssertion(rdfs:label "nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (smooth muscle cell of sphincter of pupil) @@ -37303,7 +36986,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2010-09-13T02:37:23Z") AnnotationAssertion( "FMA:72209") -AnnotationAssertion( "subcapsular thymic epithelial cell") +AnnotationAssertion(Annotation( "PMID:18194204") Annotation( "PMID:2694455") "subcapsular thymic epithelial cell") AnnotationAssertion(rdfs:label "type-1 epithelial cell of thymus") SubClassOf( ) @@ -37382,7 +37065,6 @@ SubClassOf( (endocrine-paracrine cell of prostate gland) AnnotationAssertion(Annotation( "GOC:tfm") "An ecto-epithelial cell of the prostate gland that secretes hormones.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-14T03:01:58Z") AnnotationAssertion( "CALOHA:TS-1280") @@ -37390,7 +37072,6 @@ AnnotationAssertion( "FMA:86774") AnnotationAssertion( "glandular cell of prostate") AnnotationAssertion( "neuro-epithelial cell of prostate gland") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endocrine-paracrine cell of prostate gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -37421,24 +37102,18 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-2040") AnnotationAssertion( "FMA:70333") AnnotationAssertion(rdfs:label "neural cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (connective tissue cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-15T03:01:54Z") AnnotationAssertion( "CALOHA:TS-2096") AnnotationAssertion( "FMA:63875") AnnotationAssertion( "MESH:D003239") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "connective tissue cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (embryonic cell (metazoa)) @@ -37450,7 +37125,7 @@ AnnotationAssertion( "FMA:82841") AnnotationAssertion( "WBbt:0007028") AnnotationAssertion(rdfs:label "embryonic cell (metazoa)") -SubClassOf( ) +SubClassOf( ) # Class: (amniocyte) @@ -37475,21 +37150,40 @@ AnnotationAssertion(rdfs:label "myoe EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (mammary alveolar cell) +# Class: (lactocyte) -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "The milk-producing cell of the alveolar unit that emerges during pregnancy.") +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") Annotation( "PMID:28717367") Annotation( "PMID:35091553") Annotation( "PMID:35377806") Annotation( "doi:10.1177/156482659601700404") "A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion( "2010-09-20T01:30:57Z") +AnnotationAssertion(Annotation( "PMID:19022771") "mammary alveolar cell") AnnotationAssertion( "FMA:74506") AnnotationAssertion( "FMA:79866") AnnotationAssertion( "epithelial cell of lactiferous gland") +AnnotationAssertion(Annotation( "PMID:35091553") "lactaction-associated mammary epithelial cell") +AnnotationAssertion(Annotation( "PMID:35091553") "lactation-derived mammary cell") AnnotationAssertion( "luminal cell of alveolus of lactiferous gland") AnnotationAssertion( "mammary alveolar epithelial cell") AnnotationAssertion( "mammary gland alveolar epithelial cell") -AnnotationAssertion(rdfs:label "mammary alveolar cell") +AnnotationAssertion(Annotation( "PMID:35091553") Annotation( ) "LMC") +AnnotationAssertion(rdfs:label "lactocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (luminal epithelial cell of mammary gland) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-20T01:37:53Z") +AnnotationAssertion(Annotation( "PMID:21930782") "mature luminal cell") +AnnotationAssertion( "FMA:73280") +AnnotationAssertion(rdfs:label "luminal epithelial cell of mammary gland") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (mammary gland epithelial cell) @@ -37501,7 +37195,6 @@ AnnotationAssertion( "mammary epithelial cell") AnnotationAssertion(rdfs:label "mammary gland epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (bronchial epithelial cell) @@ -37611,7 +37304,6 @@ AnnotationAssertion( AnnotationAssertion( "pancreatic endocrine progenitor") AnnotationAssertion( "pancreatic islet progenitor cell") AnnotationAssertion(rdfs:label "progenitor cell of endocrine pancreas") -SubClassOf( ) SubClassOf( ) # Class: (gestational hematopoietic stem cell) @@ -37660,7 +37352,7 @@ AnnotationAssertion( "2010-09-22T01:40:44Z") AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") "granule cell precursor") AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") "granule cell progenitor") -AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") Annotation( ) "GCP") +AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") Annotation( ) "GCP") AnnotationAssertion(rdfs:label "cerebellar granule cell precursor") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -37745,19 +37437,6 @@ AnnotationAssertion(rdfs:label "resp EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (somatic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T09:44:42Z") -AnnotationAssertion( "BTO:0001268") -AnnotationAssertion( "FMA:72300") -AnnotationAssertion( "WBbt:0008378") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "somatic cell") -SubClassOf( ) -SubClassOf( ) - # Class: (myotube) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:tfm") Annotation( "ISBN:0323052908") Annotation( "PMID:22274696") "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts.") @@ -37786,7 +37465,6 @@ AnnotationAssertion( AnnotationAssertion( "Schwann cell precursor cell") AnnotationAssertion(rdfs:label "Schwann cell precursor") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (immature Schwann cell) @@ -37917,8 +37595,8 @@ AnnotationAssertion( AnnotationAssertion(Annotation( "PMID:2253328") "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell") AnnotationAssertion(Annotation( ) Annotation( "PMID:24133281") "oligodendrocyte/type-2 astrocyte progenitor cell") AnnotationAssertion( "MESH:D000073637") -AnnotationAssertion(Annotation( "PMID:24133281") Annotation( ) "O-2A/OPC") -AnnotationAssertion(Annotation( "PMID:11756508") Annotation( ) "O2A/OPC") +AnnotationAssertion(Annotation( "PMID:24133281") Annotation( ) "O-2A/OPC") +AnnotationAssertion(Annotation( "PMID:11756508") Annotation( ) "O2A/OPC") AnnotationAssertion( ) AnnotationAssertion(Annotation( "ISBN:9780702028991") Annotation( "PMID:10704434") Annotation( "PMID:2182078") rdfs:comment "This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991).") AnnotationAssertion(rdfs:label "oligodendrocyte precursor cell") @@ -38035,8 +37713,6 @@ AnnotationAssertion( "2010-12-03T03:17:05Z") AnnotationAssertion(rdfs:label "dermal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (hair follicle melanocyte) @@ -38046,7 +37722,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "hair follicle melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial melanocyte) @@ -38057,7 +37732,6 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "epithelial melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (retinal melanocyte) @@ -38067,8 +37741,6 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (strial intermediate cell) @@ -38110,9 +37782,7 @@ AnnotationAssertion( "heart cell") AnnotationAssertion(rdfs:comment "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.") AnnotationAssertion(rdfs:label "cardiocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (spongiotrophoblast cell) @@ -38225,8 +37895,6 @@ AnnotationAssertion(Annotation( "GOC:tfm") "uterine cervix epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of cervix") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (epithelial cell of amnion) @@ -38239,8 +37907,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of amnion") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (amnion mesenchymal stem cell) @@ -38282,8 +37948,10 @@ EquivalentClasses( ObjectIntersection # Class: (chorionic membrane mesenchymal stem cell) AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of the chorionic membrane.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T03:04:35Z") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "chorionic membrane mesenchymal stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -38310,7 +37978,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:comment "See CL:0002619.") AnnotationAssertion(rdfs:label "embryonic blood vessel endothelial progenitor cell") SubClassOf( ) -SubClassOf( ) # Class: (fibroblast of the aortic adventitia) @@ -38369,12 +38036,10 @@ SubClassOf(Annotation( # Class: (fibroblast of lung) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of lung.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T05:11:03Z") AnnotationAssertion( "BTO:0000764") AnnotationAssertion( "CALOHA:TS-0575") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "fibroblast of lung") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -38409,8 +38074,10 @@ SubClassOf(Annotation( # Class: (fibroblast of pulmonary artery) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of pulmonary artery.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T05:22:27Z") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "fibroblast of pulmonary artery") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -38421,9 +38088,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2011-03-01T04:11:01Z") AnnotationAssertion(rdfs:label "hair follicle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (inner root sheath cell) @@ -38433,7 +38098,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "inner root sheath cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) # Class: (outer root sheath cell) @@ -38443,8 +38107,6 @@ AnnotationAssertion( "2011-03-01T04:29:47Z") AnnotationAssertion(rdfs:label "outer root sheath cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) # Class: (hair germinal matrix cell) @@ -38553,7 +38215,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "placental epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesenteric preadipocyte) @@ -38631,9 +38292,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal pigment epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (smooth muscle cell of the umbilical vein) @@ -38666,9 +38325,11 @@ SubClassOf(Annotation( # Class: (smooth muscle cell of the pulmonary artery) AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle of the pulmonary artery.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-03-06T05:01:28Z") AnnotationAssertion( "BTO:0003336") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "smooth muscle cell of the pulmonary artery") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -38946,8 +38607,6 @@ AnnotationAssertion( "2011-03-14T12:46:28Z") AnnotationAssertion(rdfs:label "gingival epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (prostate stromal cell) @@ -39001,8 +38660,6 @@ AnnotationAssertion( "2011-07-08T12:11:38Z") AnnotationAssertion(rdfs:label "epithelial cell of anal column") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (keratinized epithelial cell of the anal canal) @@ -39098,7 +38755,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2011-07-11T03:15:38Z") AnnotationAssertion(Annotation( "PMID:17519333") Annotation( "PMID:19745164") "cardiovascular progenitor cell") -AnnotationAssertion(Annotation( "PMID:19745164") Annotation( ) "CPC") +AnnotationAssertion(Annotation( "PMID:19745164") Annotation( ) "CPC") AnnotationAssertion(rdfs:comment "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.") AnnotationAssertion(rdfs:label "cardioblast") SubClassOf( ) @@ -39149,11 +38806,11 @@ SubClassOf(Annotation( # Class: (kidney cortical cell) +AnnotationAssertion( "A cell that is part of a cortex of kidney.") AnnotationAssertion( ) AnnotationAssertion( "2011-10-25T03:49:41Z") AnnotationAssertion(rdfs:label "kidney cortical cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (spinal cord interneuron) @@ -39166,9 +38823,10 @@ SubClassOf(Annotation( # Class: (ionocyte) AnnotationAssertion(Annotation( "PMID:17555741") Annotation( "PMID:19268451") "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment.") +AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ionocyte") SubClassOf( ) -SubClassOf( ) # Class: (macular hair cell) @@ -39190,7 +38848,7 @@ AnnotationAssertion(Annotation( "multi-ciliated cell"@en) AnnotationAssertion( "multiciliated cell"@en) AnnotationAssertion( "multiciliated epithelial cell"@en) -AnnotationAssertion(Annotation( ) "MCC"@en) +AnnotationAssertion(Annotation( ) "MCC"@en) AnnotationAssertion(rdfs:label "multi-ciliated epithelial cell") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39247,7 +38905,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:comment "unsure of neural crest contribution. In VSAO we have develops_from CL:0000008") AnnotationAssertion(rdfs:label "preameloblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39260,7 +38917,7 @@ AnnotationAssertion( AnnotationAssertion(Annotation( "GO_REF:0000034") "scleroblast") AnnotationAssertion(rdfs:comment "Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)") AnnotationAssertion(rdfs:label "skeletogenic cell") -SubClassOf( ) +SubClassOf( ) # Class: (precementoblast) @@ -39269,7 +38926,6 @@ AnnotationAssertion( "2012-06-15T04:37:13Z") AnnotationAssertion(rdfs:label "precementoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (preodontoblast) @@ -39279,7 +38935,6 @@ AnnotationAssertion( "2012-06-15T05:15:11Z") AnnotationAssertion(rdfs:label "preodontoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39300,7 +38955,6 @@ AnnotationAssertion( "2012-06-27T10:44:01Z") AnnotationAssertion(rdfs:label "prechondroblast") SubClassOf( ) -SubClassOf( ) # Class: (preosteoblast) @@ -39310,7 +38964,6 @@ AnnotationAssertion( AnnotationAssertion( "osteoprogenitor cell") AnnotationAssertion(rdfs:label "preosteoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39329,8 +38982,6 @@ SubClassOf( ObjectSomeValuesFrom( (non-striated muscle cell) AnnotationAssertion(Annotation( "GOC:DOS") "Any muscle cell in which the fibers are not organised into sarcomeres.") -AnnotationAssertion( ) -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "non-striated muscle cell") SubClassOf( ) @@ -39394,23 +39045,21 @@ AnnotationAssertion(Annotation( "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.") AnnotationAssertion(rdfs:label "adult skeletal muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (somatic muscle myoblast) AnnotationAssertion( "A myoblast that is commited to developing into a somatic muscle.") AnnotationAssertion(rdfs:label "somatic muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (mesenchymal cell) AnnotationAssertion( "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration.") +AnnotationAssertion( ) AnnotationAssertion( "mesenchyme cell") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesenchymal cell") -SubClassOf( ) -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39433,7 +39082,6 @@ AnnotationAssertion( "pancreatic endocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (noradrenergic neuron) @@ -39482,8 +39130,6 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mural cell"@en) -SubClassOf( ) -SubClassOf( ) SubClassOf( ) # Class: (microcirculation associated smooth muscle cell) @@ -39552,8 +39198,6 @@ AnnotationAssertion( "PMID:12021768") AnnotationAssertion(rdfs:label "compound eye retinal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) -SubClassOf( ) # Class: (retinal cell) @@ -40035,11 +39679,13 @@ EquivalentClasses( ObjectIntersection # Class: (epithelial cell of endometrial gland) AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An epithelial cell that is part of an endometrial gland.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2021-11-30T16:13:30Z"^^xsd:dateTime) AnnotationAssertion( "EFO:0010710") AnnotationAssertion( "endometrial glandular epithelial cell") AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of endometrial gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -40143,20 +39789,34 @@ EquivalentClasses( ObjectIntersection # Class: (hepatic portal fibroblast) AnnotationAssertion(Annotation( "PMID:20209607") Annotation( "PMID:24814904") Annotation( "https://orcid.org/0000-0001-7655-4833") "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2022-03-17T12:00:44Z"^^xsd:dateTime) AnnotationAssertion( "portal fibroblast") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "hepatic portal fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lymph node lymphatic vessel endothelial cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-7655-4833") "An endothelial cell located in a lymph node lymphatic vessel.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lymph node lymphatic vessel endothelial cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1472") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (progenitor cell of mammary luminal epithelium) + +AnnotationAssertion(Annotation( "PMID:19063729") Annotation( "PMID:20346151") Annotation( "PMID:21930782") Annotation( "https://orcid.org/0000-0003-4412-7970") "A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells.") +AnnotationAssertion( ) +AnnotationAssertion( "luminal progenitor cell") +AnnotationAssertion( "progenitor cell of luminal mammary epithelium") +AnnotationAssertion(rdfs:label "progenitor cell of mammary luminal epithelium") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (stromal cell of bone marrow) AnnotationAssertion( "A stromal cell that is part_of a bone marrow.") @@ -40196,8 +39856,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:mtg_heart") "A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers.") AnnotationAssertion( "AV bundle cell") AnnotationAssertion(rdfs:label "atrioventricular bundle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac blood vessel endothelial cell) @@ -40207,8 +39866,7 @@ EquivalentClasses( ObjectIntersection # Class: (His-Purkinje system cell) AnnotationAssertion(rdfs:label "His-Purkinje system cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac endothelial cell) @@ -40261,7 +39919,7 @@ AnnotationAssertion( "MESH:D015053") AnnotationAssertion(rdfs:label "zygote"@en) AnnotationAssertion(rdfs:seeAlso ) -SubClassOf( ) +SubClassOf( ) # Class: (cardiac glial cell) @@ -40273,7 +39931,6 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion( "MESH:D032386") AnnotationAssertion(rdfs:label "cardiac myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (cardiac neuron) @@ -40353,8 +40010,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "motile sperm cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (flagellated sperm cell) @@ -40362,7 +40017,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "flagellated sperm cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (mesothelial cell of epicardium) @@ -40450,8 +40104,7 @@ SubClassOf( "GOC:dos") "A cell that, by division or terminal differentiation, can give rise to other cell types.") AnnotationAssertion(rdfs:comment "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.") AnnotationAssertion(rdfs:label "precursor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (astrocyte of the forebrain) @@ -40494,9 +40147,11 @@ SubClassOf( (prostate neuroendocrine cell) AnnotationAssertion(Annotation( "PMID:33842835") Annotation( "http://orcid.org/0000-0001-7772-9578") "A neuroendocrine cell that is part of the prostate epithelium.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "neuroendocrine cell of prostate epithelium") AnnotationAssertion( "neuroendocrine cell of the prostate") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "prostate neuroendocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -40567,7 +40222,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial serous cell"@en) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (tracheobronchial chondrocyte) @@ -40584,10 +40238,12 @@ EquivalentClasses( ObjectIntersection # Class: (tracheobronchial goblet cell) AnnotationAssertion( "Any goblet cell that is part of the tracheobronchial epithelium.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2020-05-07T18:14:52Z"^^xsd:dateTime) AnnotationAssertion( "goblet cell of tracheobronchial tree") AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial goblet cell"@en) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -40745,8 +40401,6 @@ EquivalentClasses( ObjectIntersection # Class: (lung goblet cell) -AnnotationAssertion( ) -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung goblet cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -40755,8 +40409,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:25311230") "A cell that is part of a cardiac valve.") AnnotationAssertion(Annotation( "PMID:30796046") "heart valve cell") AnnotationAssertion(rdfs:label "cardiac valve cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (growth plate cartilage chondrocyte) @@ -40773,7 +40426,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:33355253") Annotation( "doi:10.3109/01902148209069653") Annotation( "doi:10.7554/eLife.78216") "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.") AnnotationAssertion( ) AnnotationAssertion(Annotation( "PMID:33355253") "pulmonary neuroendocrine cell") -AnnotationAssertion(Annotation( "PMID:33355253") Annotation( ) "PNEC") +AnnotationAssertion(Annotation( "PMID:33355253") Annotation( ) "PNEC") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung neuroendocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -40803,14 +40456,12 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung ciliated cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (lung secretory cell) AnnotationAssertion(rdfs:label "lung secretory cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (trophectodermal cell) @@ -40936,8 +40587,6 @@ AnnotationAssertion(Annotation( "FMA:256165") AnnotationAssertion(rdfs:label "epithelial cell of urethra") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of dura mater) @@ -40946,8 +40595,6 @@ AnnotationAssertion( "FMA:256516") "squamous mesothelial cell of dura mater") AnnotationAssertion(rdfs:label "mesothelial cell of dura mater") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (fibroblast of papillary layer of dermis) @@ -41171,8 +40818,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous cell of epithelium of trachea") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (serous cell of epithelium of bronchus) @@ -41182,7 +40827,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous cell of epithelium of bronchus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (serous cell of epithelium of terminal bronchiole) @@ -41190,7 +40834,6 @@ AnnotationAssertion(Annotation( "FMA:263082") AnnotationAssertion(rdfs:label "serous cell of epithelium of terminal bronchiole") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (serous cell of epithelium of lobular bronchiole) @@ -41198,7 +40841,6 @@ AnnotationAssertion(Annotation( "FMA:263084") AnnotationAssertion(rdfs:label "serous cell of epithelium of lobular bronchiole") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (transitional myocyte of interatrial septum) @@ -41311,7 +40953,6 @@ AnnotationAssertion(Annotation( "melanocyte of eyelid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (endothelial cell of venous sinus of red pulp of spleen) @@ -41343,8 +40984,6 @@ AnnotationAssertion(Annotation( "FMA:63602") "epithelial cell of vermiform appendix") AnnotationAssertion(rdfs:label "epithelial cell of appendix") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (myocyte of sinoatrial node) @@ -41352,7 +40991,6 @@ AnnotationAssertion(Annotation( "FMA:67102") AnnotationAssertion(Annotation( "FMA:67102") "SA nodal myocyte") AnnotationAssertion(Annotation( "GOC:pr") "SA node cardiac muscle cell") -AnnotationAssertion(Annotation( "FMA:67102") "myocyte of sinoatrial node") AnnotationAssertion(Annotation( "GOC:pr") "sinoatrial node cell") AnnotationAssertion( "sinoatrial node myocyte") AnnotationAssertion(Annotation( "FMA:67102") "sinuatrial node myocyte") @@ -41422,8 +41060,6 @@ AnnotationAssertion(Annotation( "FMA:67780") AnnotationAssertion(rdfs:label "epithelial cell of gallbladder") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (myoepithelial cell of sweat gland) @@ -41508,7 +41144,6 @@ AnnotationAssertion( "conjunctival epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of lacrimal canaliculus) @@ -41516,8 +41151,6 @@ AnnotationAssertion(Annotation( "FMA:70553") AnnotationAssertion(rdfs:label "epithelial cell of lacrimal canaliculus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of external acoustic meatus) @@ -41525,8 +41158,6 @@ AnnotationAssertion(Annotation( "FMA:70555") AnnotationAssertion(rdfs:label "epithelial cell of external acoustic meatus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of lacrimal duct) @@ -41542,8 +41173,6 @@ AnnotationAssertion(Annotation( "FMA:70560") AnnotationAssertion(rdfs:label "epithelial cell of lacrimal sac") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of nasolacrimal duct) @@ -41577,8 +41206,6 @@ AnnotationAssertion(Annotation( "FMA:70615") AnnotationAssertion(rdfs:label "mesothelial cell of anterior chamber of eye") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (myoepithelial cell of dilator pupillae) @@ -41603,8 +41230,6 @@ AnnotationAssertion(Annotation( "FMA:70952") AnnotationAssertion(rdfs:label "epithelial cell of sweat gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (epithelial cell of nephron) @@ -41612,8 +41237,6 @@ AnnotationAssertion(Annotation( "FMA:70965") AnnotationAssertion(rdfs:label "epithelial cell of nephron") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (epithelial cell of glomerular capsule) @@ -41624,8 +41247,6 @@ AnnotationAssertion( "FMA:70966") "epithelial cell of Bowman's capsule") AnnotationAssertion(rdfs:label "epithelial cell of glomerular capsule") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -41647,8 +41268,6 @@ AnnotationAssertion(Annotation( "FMA:70980") AnnotationAssertion(rdfs:label "epithelial cell of intermediate tubule") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (kidney collecting duct epithelial cell) @@ -41670,8 +41289,6 @@ AnnotationAssertion(Annotation( "FMA:72142") AnnotationAssertion(rdfs:label "mesothelial cell of parietal peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesothelial cell of visceral peritoneum) @@ -41681,8 +41298,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesothelial cell of visceral peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (melanocyte of skin) @@ -41695,7 +41310,6 @@ AnnotationAssertion( "melanocyte of skin") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (chromaffin cell of ovary) @@ -41782,8 +41396,10 @@ SubClassOf(Annotation( # Class: (basal cell of urothelium) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "doi:10.1038/s41385-022-00565-0") "A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role.") +AnnotationAssertion( ) AnnotationAssertion( "FMA:84150") AnnotationAssertion(Annotation( "doi:10.1007/978-3-030-14366-4_8") Annotation( "doi:10.1111/cpr.13170") "urothelial basal cell") +AnnotationAssertion( ) AnnotationAssertion(Annotation( "doi:10.1038/s41385-022-00565-0") rdfs:comment "It has been noted in at least some mammalian species that the urothelial basal cell type is distinguished by expression of high levels of cytokeratin-5 (CK5), p63 and the signalling molecule Sonic hedgehog (Shh). Similar to intermediate cells, the urothelial basal cell type expresses CK17 but is negative for uroplakins (UPK) and CK20. Urothelial basal cells have also been noted to be smaller in diameter than urothelial intermediate cells.") AnnotationAssertion(rdfs:label "basal cell of urothelium") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -41829,8 +41445,6 @@ AnnotationAssertion( "FMA:86736") "peritoneal mesothelial cell") AnnotationAssertion(rdfs:label "mesothelial cell of peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of pleura) @@ -41839,8 +41453,6 @@ AnnotationAssertion( "FMA:86737") "pleural mesothelial cell") AnnotationAssertion(rdfs:label "mesothelial cell of pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of parietal pleura) @@ -41848,16 +41460,15 @@ AnnotationAssertion(Annotation( "FMA:86738") AnnotationAssertion(rdfs:label "mesothelial cell of parietal pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesothelial cell of visceral pleura) AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the visceral pleura.") +AnnotationAssertion( ) AnnotationAssertion( "FMA:86739") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesothelial cell of visceral pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (nephron tubule epithelial cell) @@ -41882,44 +41493,38 @@ SubClassOf( ObjectSomeValuesFrom( (kidney cell) +AnnotationAssertion( "A cell that is part of a kidney.") AnnotationAssertion( "KUPO:0001010") AnnotationAssertion(rdfs:label "kidney cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney interstitial cell) +AnnotationAssertion( "A cell that is part of kidney interstitium.") AnnotationAssertion( "KUPO:0001013") AnnotationAssertion(rdfs:label "kidney interstitial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney medulla cell) +AnnotationAssertion( "A cell that is part of a renal medulla.") AnnotationAssertion( "KUPO:0001017") AnnotationAssertion(rdfs:label "kidney medulla cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney pelvis cell) +AnnotationAssertion( "A cell that is part of a renal pelvis.") AnnotationAssertion( "KUPO:0001018") AnnotationAssertion(rdfs:label "kidney pelvis cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney tubule cell) +AnnotationAssertion( "A cell that is part of a nephron tubule.") AnnotationAssertion( "KUPO:0001020") AnnotationAssertion(rdfs:label "kidney tubule cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney glomerular epithelial cell) @@ -41931,36 +41536,33 @@ SubClassOf( ObjectSomeValuesFrom( (kidney medulla collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of a renal medulla collecting duct.") AnnotationAssertion( "KUPO:0001060") AnnotationAssertion(rdfs:label "kidney medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney inner medulla collecting duct epithelial cell) AnnotationAssertion( "An epithelial cell that is part of some inner medullary collecting duct.") AnnotationAssertion( "KUPO:0001061") AnnotationAssertion(rdfs:label "kidney inner medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (kidney outer medulla collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of an outer medullary collecting duct.") AnnotationAssertion( "KUPO:0001062") AnnotationAssertion(rdfs:label "kidney outer medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (kidney cortex collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of a cortical collecting duct.") AnnotationAssertion( "KUPO:0001063") AnnotationAssertion(rdfs:label "kidney cortex collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney papillary duct principal epithelial cell) @@ -41993,16 +41595,14 @@ SubClassOf( ObjectSomeValuesFrom( "KUPO:0001115") AnnotationAssertion(rdfs:label "lower urinary tract cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (ureteral cell) AnnotationAssertion( "KUPO:0001116") AnnotationAssertion(rdfs:label "ureteral cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney nerve cell) @@ -42287,7 +41887,9 @@ SubClassOf( ObjectSomeValuesFrom( (ureter smooth muscle cell) +AnnotationAssertion( ) AnnotationAssertion( "KUPO:0001118") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ureter smooth muscle cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -42673,11 +42275,11 @@ SubClassOf( (kidney collecting duct cell) +AnnotationAssertion( "A cell that is part of a collecting duct of renal tubule.") AnnotationAssertion( "KUPO:0001012") AnnotationAssertion( "Wikipedia:Kidney_collecting_duct_cell") AnnotationAssertion(rdfs:label "kidney collecting duct cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (vasa recta descending limb cell) @@ -42725,16 +42327,14 @@ AnnotationAssertion( "KUPO:0001120") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bladder cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (urethra cell) AnnotationAssertion( "KUPO:0001123") AnnotationAssertion(rdfs:label "urethra cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (bladder urothelial cell) @@ -42834,18 +42434,18 @@ EquivalentClasses( ObjectIntersection # Class: (lung endothelial cell) -AnnotationAssertion( ) AnnotationAssertion( "endothelial cell of lung") AnnotationAssertion( "pulmonary vessel endothelial cell") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (pulmonary artery endothelial cell) +AnnotationAssertion( ) AnnotationAssertion( "BTO:0001141") AnnotationAssertion(Annotation( "BTO:0001141") "PAEC cell") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pulmonary artery endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) @@ -42872,7 +42472,7 @@ SubClassOf( ObjectSomeValuesFrom( "NPX:PDR") Annotation( "https://orcid.org/0000-0001-5208-3432") "A vascular endothelial cell found in colon blood vessels.") AnnotationAssertion( "CALOHA:TS-2397") -AnnotationAssertion(Annotation( "CALOHA:TS-2397") Annotation( ) "colon endothelial cells") +AnnotationAssertion(Annotation( "CALOHA:TS-2397") Annotation( ) "colon endothelial cells") AnnotationAssertion(Annotation( "CALOHA:TS-2397") "colonic endothelial cell") AnnotationAssertion(rdfs:label "colon endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -43160,7 +42760,9 @@ EquivalentClasses( ObjectIntersection # Class: (articular chondrocyte) AnnotationAssertion(Annotation( "NPX:PDR") "Chondrocyte forming the hyaline cartilage found in joints.") +AnnotationAssertion( ) AnnotationAssertion( "CALOHA:TS-0056") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "articular chondrocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -43207,7 +42809,6 @@ AnnotationAssertion( "These cells are found primarily, but not exclusively, in primates including humans") AnnotationAssertion(rdfs:label "epidermal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (peripheral blood mononuclear cell) @@ -43240,8 +42841,7 @@ AnnotationAssertion( "2014-03-26T22:14:56Z") AnnotationAssertion( "CL:2000004") AnnotationAssertion(rdfs:label "pituitary gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (brain macroglial cell) @@ -43378,7 +42978,7 @@ AnnotationAssertion( "2014-06-24T23:16:53Z") AnnotationAssertion( "CL:2000020") AnnotationAssertion(rdfs:label "inner cell mass cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (sebaceous gland cell) @@ -43387,8 +42987,7 @@ AnnotationAssertion( "2014-06-24T23:17:00Z") AnnotationAssertion( "CL:2000021") AnnotationAssertion(rdfs:label "sebaceous gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac septum cell) @@ -43397,8 +42996,7 @@ AnnotationAssertion( "2014-06-24T23:17:07Z") AnnotationAssertion( "CL:2000022") AnnotationAssertion(rdfs:label "cardiac septum cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (spinal cord ventral column interneuron) @@ -43461,8 +43059,7 @@ AnnotationAssertion( "2014-06-25T01:17:50Z") AnnotationAssertion( "CL:2000030") AnnotationAssertion(rdfs:label "hypothalamus cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lateral line ganglion neuron) @@ -43567,7 +43164,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000045") AnnotationAssertion(rdfs:label "foreskin melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (ventricular cardiac muscle cell) @@ -43662,11 +43258,9 @@ EquivalentClasses( ObjectIntersection # Class: (prostate gland microvascular endothelial cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a prostate gland.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:46:27Z") AnnotationAssertion( "CL:2000059") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=4400") AnnotationAssertion(rdfs:label "prostate gland microvascular endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -43689,9 +43283,11 @@ EquivalentClasses( ObjectIntersection # Class: (placental amniotic mesenchymal stromal cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mesenchymal stem cell that is part of a placenta.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:51:11Z") AnnotationAssertion( "CL:2000061") +AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7140") AnnotationAssertion(rdfs:label "placental amniotic mesenchymal stromal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -43699,11 +43295,9 @@ EquivalentClasses( ObjectIntersection # Class: (placental villus capillary endothelial cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any capillary endothelial cell that is part of a placenta.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:55:56Z") AnnotationAssertion( "CL:2000062") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.ncbi.nlm.nih.gov/books/NBK53245/") AnnotationAssertion(rdfs:label "placental villus capillary endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -43895,7 +43489,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000081") AnnotationAssertion(rdfs:label "melanocyte of skin of face") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (melanocyte of foreskin) @@ -43905,7 +43498,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000082") AnnotationAssertion(rdfs:label "melanocyte of foreskin") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (hair follicle dermal papilla cell of scalp) @@ -44186,7 +43778,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "brain vascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mammillary body neuron) @@ -44288,7 +43880,6 @@ AnnotationAssertion( "PMID:31819095") Annotation( "PMID:34082079") rdfs:comment "Cellular functions and extracellular interactions of choroidal melanocytes are distinct to skin melanocytes. They might have both neuroectodermal as well as mesectodermal origins.") AnnotationAssertion(rdfs:label "choroidal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (stromal cell of thymus) @@ -44353,6 +43944,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "kidney connecting tubule principal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (renal medullary fibroblast) @@ -44400,16 +43992,18 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2022-11-30T14:35:08Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label "interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (valve interstitial cell) AnnotationAssertion(Annotation( ) Annotation( "PMID:25311230") Annotation( "https://doi.org/10.1098/rsif.2017.0580") Annotation( "https://doi.org/10.1161/ATVBAHA.120.314789") Annotation( "https://doi.org/10.1161/JAHA.117.006339") Annotation( "https://doi.org/10.2353/ajpath.2007.070251") "An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2022-12-06T14:18:45Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VIC") +AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VIC") AnnotationAssertion( "cardiac valve interstitial cell") AnnotationAssertion(Annotation( "PMID:25311230") "valvular interstitial cell") +AnnotationAssertion( ) AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "Activated valve interstitial cells undergo continual turn over into deactivated fibroblasts and other cell fates (such as apoptosis).") AnnotationAssertion(rdfs:label "valve interstitial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -44420,7 +44014,7 @@ SubClassOf( ObjectSomeValuesFrom( "PMID:25311230") "An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") AnnotationAssertion( ) AnnotationAssertion( "2022-12-09T11:58:49Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VEC") +AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VEC") AnnotationAssertion(Annotation( "PMID:25311230") "valvular endothelial cell") AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "At least in some mammalian species, a valve endothelial cell expresses CD31. Valve endothelial cells can undergo an endothelial to mesenchymal transition to acquire a fibroblast or myofibroblast phenotype that leads to changes in the microenvironmental signals and facilitates tissue regeneration.") AnnotationAssertion(rdfs:label "valve endothelial cell") @@ -44439,7 +44033,7 @@ SubClassOf( ObjectSomeValuesFrom( ) Annotation( "DOI:10.1177/154405910208100806") "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation.") AnnotationAssertion( "2023-01-10T14:02:02Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) "DPSC") +AnnotationAssertion(Annotation( ) "DPSC") AnnotationAssertion(rdfs:label "dental pulp stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -44456,6 +44050,16 @@ AnnotationAssertion(Annotation( "endometrial ciliated epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (ureteric bud cell) + +AnnotationAssertion(Annotation( "PMID:17133361") Annotation( "PMID:24183650") Annotation( "PMID:9374839") "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion.") +AnnotationAssertion( "https://orcid.org/0000-0002-1425-877X") +AnnotationAssertion( "2023-10-13T11:22:42Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:24183650") Annotation( ) "UB cell") +AnnotationAssertion(rdfs:label "ureteric bud cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "PMID:9374839") ObjectSomeValuesFrom( )) + # Class: (endothelial cell of venule of lymph node) AnnotationAssertion(Annotation( "PMID:28217126") "A(n) endothelial cell that is part of a(n) venule of lymph node.") @@ -44496,7 +44100,9 @@ EquivalentClasses( ObjectIntersection # Class: (serous secreting cell of bronchus submucosal gland) AnnotationAssertion(Annotation( "PMID:5487122") Annotation( "PMID:9651178") "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous secreting cell of bronchus submucosal gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -44570,7 +44176,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:25236977") Annotation( "PMID:33796062") "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons.") AnnotationAssertion( ) AnnotationAssertion( "2023-03-02T14:38:32Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) Annotation( "PMID:33796062") "retinal astroglia") +AnnotationAssertion(Annotation( "PMID:33796062") Annotation( ) "retinal astroglia") AnnotationAssertion( ) AnnotationAssertion(Annotation( "PMID:32555229") Annotation( "PMID:33796062") rdfs:comment "In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive.") AnnotationAssertion(rdfs:label "retinal astrocyte") @@ -44597,8 +44203,8 @@ AnnotationAssertion( "2023-03-16T11:31:23Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:36524131") "lung resident megakaryocyte") AnnotationAssertion(Annotation( "PMID:36524131") "lung-resident megakaryocyte") -AnnotationAssertion(Annotation( "PMID:36524131") Annotation( ) "MKL") -AnnotationAssertion(Annotation( "PMID:33351116") Annotation( ) Annotation( ) "lung MKs") +AnnotationAssertion(Annotation( "PMID:36524131") Annotation( ) "MKL") +AnnotationAssertion(Annotation( "PMID:33351116") Annotation( ) Annotation( ) "lung MKs") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung megakaryocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -44653,10 +44259,12 @@ EquivalentClasses( ObjectIntersection # Class: (lung perichondrial fibroblast) AnnotationAssertion(Annotation( "PMID:36543915") "A perichondrial fibroblast that is part of the lung.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2023-03-16T16:15:39Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:36543915") Annotation( ) "PC-fibro") +AnnotationAssertion(Annotation( "PMID:36543915") Annotation( ) "PC-fibro") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung perichondrial fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -44693,7 +44301,39 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2023-08-22T13:40:28Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label "perivascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (airway submucosal gland duct ciliated cell) + +AnnotationAssertion(Annotation( "PMID:17707699") Annotation( "PMID:30864819") "A ciliated cell that is part of a ciliated duct of an airway submucosal gland.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-09-08T10:32:27Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "airway submucosal gland duct ciliated cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (luminal adaptive secretory precursor cell of mammary gland) + +AnnotationAssertion(Annotation( "PMID:19648928") Annotation( "PMID:35617956") Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation( "https://orcid.org/0000-0001-6677-8489") "A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-10-13T13:02:55Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:35617956") "alveolar cell") +AnnotationAssertion(Annotation( "PMID:26390871") "alveolar progenitor") +AnnotationAssertion(Annotation( "doi:10.1101/2023.04.21.537845") "luminal progenitor") +AnnotationAssertion(Annotation( "PMID:20346151") "luminal progenitor cell") +AnnotationAssertion(Annotation( "PMID:37380767") "luminal secretory cell") +AnnotationAssertion(Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") "ER-negative luminal alveolar progenitor") +AnnotationAssertion(Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation( ) "AP") +AnnotationAssertion(Annotation( "PMID:35617956") Annotation( ) "AV") +AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-6677-8489") Annotation( ) "LASP") +AnnotationAssertion(Annotation( "doi:10.1101/2023.04.21.537845") Annotation( ) "LP") +AnnotationAssertion(Annotation( "PMID:37380767") Annotation( ) "LumSec") +AnnotationAssertion(rdfs:label "luminal adaptive secretory precursor cell of mammary gland") +SubClassOf( ) +SubClassOf( ) # Class: (enteroglial cell) @@ -44701,7 +44341,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2023-04-03T15:15:40Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:11169131") Annotation( "PMID:25170211") "enteric glial cell") -AnnotationAssertion(Annotation( ) Annotation( "PMID:11169131") "enteric glia") +AnnotationAssertion(Annotation( "PMID:11169131") Annotation( ) "enteric glia") AnnotationAssertion(rdfs:label "enteroglial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) @@ -44718,6 +44358,17 @@ AnnotationAssertion( "fetal pre-type II pneumocyte") SubClassOf( ) +# Class: (mesenchymal stem cell of orbital adipose tissue) + +AnnotationAssertion(Annotation( ) "Any mesenchymal stem cell of adipose tissue that is part of an orbital region.") +AnnotationAssertion( ) +AnnotationAssertion( "2023-09-18T10:43:00Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:31377878") "OAMSC") +AnnotationAssertion(Annotation( "PMID:30210548") "Orbital ASCs") +AnnotationAssertion(Annotation( "PMID:31377878") "orbital adipose-derived mesenchymal stem cell") +AnnotationAssertion(rdfs:label "mesenchymal stem cell of orbital adipose tissue") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (reproduction) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.") @@ -45091,18 +44742,8 @@ AnnotationAssertion( "GO:0001504") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "neurotransmitter uptake") -SubClassOf( ) SubClassOf( ) -# Class: (regulation of neurotransmitter levels) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates levels of neurotransmitter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001505") -AnnotationAssertion(rdfs:label "regulation of neurotransmitter levels") -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (action potential) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") Annotation( "ISBN:978-0-07-139011-8") "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.") @@ -45591,7 +45232,6 @@ AnnotationAssertion( "GO:0001695") AnnotationAssertion(rdfs:label "histamine catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (gastric acid secretion) @@ -47510,7 +47150,6 @@ AnnotationAssertion(Annotation( "GO:0002263") AnnotationAssertion(rdfs:label "cell activation involved in immune response") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (endothelial cell activation involved in immune response) @@ -47591,7 +47230,7 @@ AnnotationAssertion(Annotation( "GO:0002281") AnnotationAssertion(rdfs:label "macrophage activation involved in immune response") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (neutrophil activation involved in immune response) @@ -47937,7 +47576,6 @@ AnnotationAssertion( "leukocyte activation involved in immune response") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (cytokine production involved in immune response) @@ -52830,7 +52468,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "chromatin binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (nuclear steroid receptor activity) @@ -52924,7 +52561,21 @@ AnnotationAssertion(Annotation(rdfs:label "INF-gamma induced phosphorylation of AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino") "Reactome:R-HSA-937034") AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates NICD4") "Reactome:R-HSA-9604606") AnnotationAssertion(Annotation(rdfs:label "GTP-bound RAC1 contributes to MAPK8 activation") "Reactome:R-HSA-9673284") +AnnotationAssertion(Annotation(rdfs:label "JAK1-activated RAF1 phosphorylates MAPKs") "Reactome:R-HSA-9732753") AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation") "Reactome:R-HSA-975139") +AnnotationAssertion(Annotation(rdfs:label "PKR dimer autophosphorylates") "Reactome:R-HSA-9833820") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates eIF2-alpha") "Reactome:R-HSA-9835885") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates DHX9") "Reactome:R-HSA-9836159") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates CDK1") "Reactome:R-HSA-9836184") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates MKK6") "Reactome:R-HSA-9836322") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates TP53 tetramer") "Reactome:R-HSA-9836362") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates ILF3:ILF2") "Reactome:R-HSA-9836383") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates MAPT") "Reactome:R-HSA-9836404") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates SNCA") "Reactome:R-HSA-9836435") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates HIV tat") "Reactome:R-HSA-9836449") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates PTPN2") "Reactome:R-HSA-9836515") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates SPHK1") "Reactome:R-HSA-9836617") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates PPP2R5A") "Reactome:R-HSA-9836664") AnnotationAssertion( "protamine kinase activity") AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0004672") @@ -53121,7 +52772,7 @@ AnnotationAssertion(Annotation(rdfs:label "Src kinases phosphorylate VAV") "Reactome:R-HSA-5218828") AnnotationAssertion(Annotation(rdfs:label "SRC-1 phosphorylates PTK2-beta") "Reactome:R-HSA-5218830") AnnotationAssertion(Annotation(rdfs:label "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407") "Reactome:R-HSA-5218851") -AnnotationAssertion(Annotation(rdfs:label "AXL autophosphorylates on Y772 and Y814") "Reactome:R-HSA-5357429") +AnnotationAssertion(Annotation(rdfs:label "AXL autophosphorylates on Y779 and Y821") "Reactome:R-HSA-5357429") AnnotationAssertion(Annotation(rdfs:label "1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG") "Reactome:R-HSA-5607745") AnnotationAssertion(Annotation(rdfs:label "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan") "Reactome:R-HSA-5607750") AnnotationAssertion(Annotation(rdfs:label "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG") "Reactome:R-HSA-5621355") @@ -53216,8 +52867,8 @@ AnnotationAssertion(Annotation(rdfs:label "SRC,YES1 phosphorylate YAP1") "Reactome:R-HSA-8942607") AnnotationAssertion(Annotation(rdfs:label "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18") "Reactome:R-HSA-8948143") AnnotationAssertion(Annotation(rdfs:label "ABL1 phosphorylates YAP1") "Reactome:R-HSA-8956659") -AnnotationAssertion(Annotation(rdfs:label "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964242") -AnnotationAssertion(Annotation(rdfs:label "G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964252") +AnnotationAssertion(Annotation(rdfs:label "G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC") "Reactome:R-HSA-8964242") +AnnotationAssertion(Annotation(rdfs:label "G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC") "Reactome:R-HSA-8964252") AnnotationAssertion(Annotation(rdfs:label "JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4") "Reactome:R-HSA-8983872") AnnotationAssertion(Annotation(rdfs:label "Phospho-JAK2 phosphorylates EPOR") "Reactome:R-HSA-9006323") AnnotationAssertion(Annotation(rdfs:label "JAK2 transphosphorylates and is activated in response to Erythropoietin") "Reactome:R-HSA-9006332") @@ -53309,9 +52960,10 @@ AnnotationAssertion(Annotation(rdfs:label "ALK mutants phosphorylate STAT3") "Reactome:R-HSA-9712086") AnnotationAssertion(Annotation(rdfs:label "ALK fusions phosphorylate FRS") "Reactome:R-HSA-9712087") AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates RHOU") "Reactome:R-HSA-9726848") +AnnotationAssertion(Annotation(rdfs:label "JAK1-mediated phosphorylation of RAF1") "Reactome:R-HSA-9732738") AnnotationAssertion(Annotation(rdfs:label "CSF1R trans-autophosphorylates on tyrosine-561") "Reactome:R-HSA-9733314") AnnotationAssertion(Annotation(rdfs:label "Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL") "Reactome:R-HSA-9733323") -AnnotationAssertion(Annotation(rdfs:label "BACH1 is phosphorylated at tyrosine 486") "Reactome:R-HSA-9762209") +AnnotationAssertion(Annotation(rdfs:label "BACH1 is phosphorylated at tyrosine 483") "Reactome:R-HSA-9762209") AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylation of GHR") "Reactome:R-HSA-982807") AnnotationAssertion(Annotation(rdfs:label "p-6Y-SYK phosphorylates BLNK (SLP65)") "Reactome:R-HSA-983703") AnnotationAssertion(Annotation(rdfs:label "SYK autophosphorylates at the activated BCR") "Reactome:R-HSA-983707") @@ -53647,8 +53299,6 @@ SubClassOf( "GOC:ai") Annotation( "GOC:dgf") "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.") AnnotationAssertion( "GO:0005478") -AnnotationAssertion(Annotation(rdfs:label "Virion-associated M2 protein mediated ion infusion") "Reactome:R-HSA-168313") -AnnotationAssertion(Annotation(rdfs:label "SMAD7:SMURF1 complex is exported to the cytosol") "Reactome:R-HSA-178215") AnnotationAssertion( "molecular_function") AnnotationAssertion( "carrier") AnnotationAssertion( "GO:0005215") @@ -55724,7 +55374,6 @@ AnnotationAssertion( "GO:0006581") AnnotationAssertion(rdfs:label "acetylcholine catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (catecholamine metabolic process) @@ -57663,7 +57312,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.") AnnotationAssertion(rdfs:label "neurotransmitter secretion") -SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -58568,7 +58216,7 @@ AnnotationAssertion( "GO:0007560") AnnotationAssertion(rdfs:label "imaginal disc morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -59415,7 +59063,6 @@ AnnotationAssertion( "GO:0008291") AnnotationAssertion(rdfs:label "acetylcholine metabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (acetylcholine biosynthetic process) @@ -59428,7 +59075,6 @@ AnnotationAssertion( "GO:0008292") AnnotationAssertion(rdfs:label "acetylcholine biosynthetic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (isoprenoid biosynthetic process) @@ -65889,7 +65535,6 @@ AnnotationAssertion( "GO:0019215") AnnotationAssertion(rdfs:label "intermediate filament binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (regulation of lipid metabolic process) @@ -66496,6 +66141,14 @@ AnnotationAssertion( "isoprenoid binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (immunoglobulin binding) + +AnnotationAssertion(Annotation( "GOC:ma") "Binding to an immunoglobulin.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0019865") +AnnotationAssertion(rdfs:label "immunoglobulin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (outer membrane) AnnotationAssertion(Annotation( "GOC:go_curators") "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.") @@ -70039,6 +69692,7 @@ AnnotationAssertion( "GO:0022892") AnnotationAssertion(Annotation(rdfs:label "Egress of internalized antigen to the cytosol via sec61") "Reactome:R-HSA-1236947") AnnotationAssertion(Annotation(rdfs:label "SLC2A9 transports Fru, Glc, urate") "Reactome:R-HSA-429036") +AnnotationAssertion(Annotation(rdfs:label "MATEs mediate extrusion of xenobiotics") "Reactome:R-HSA-434650") AnnotationAssertion(Annotation(rdfs:label "Defective SLC2A9 does not transport Fru, Glc, urate") "Reactome:R-HSA-5638209") AnnotationAssertion(Annotation(rdfs:label "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA") "Reactome:R-HSA-5671707") AnnotationAssertion(Annotation(rdfs:label "An unknown carrier transports cytosolic glyoxylate to the peroxisome") "Reactome:R-HSA-6784434") @@ -71422,7 +71076,6 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.") AnnotationAssertion( "GO:0019613") -AnnotationAssertion( "MetaCyc:7ALPHADEHYDROX-PWY") AnnotationAssertion( "bile acid breakdown") AnnotationAssertion( "bile acid catabolism") AnnotationAssertion( "bile acid degradation") @@ -71460,7 +71113,6 @@ AnnotationAssertion( "A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity'") AnnotationAssertion(rdfs:label "neurotransmitter receptor activity") SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -76403,6 +76055,7 @@ EquivalentClasses( ObjectIntersection # Class: (regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034103") AnnotationAssertion(rdfs:label "regulation of tissue remodeling") @@ -76411,6 +76064,7 @@ EquivalentClasses( ObjectIntersection # Class: (negative regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "negative regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034104") AnnotationAssertion(rdfs:label "negative regulation of tissue remodeling") @@ -76419,6 +76073,7 @@ EquivalentClasses( ObjectIntersection # Class: (positive regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "positive regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034105") AnnotationAssertion(rdfs:label "positive regulation of tissue remodeling") @@ -80072,49 +79727,6 @@ AnnotationAssertion( "negative regulation of T cell proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (neurotransmitter metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( ) -AnnotationAssertion( "neurotransmitter metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042133") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter metabolic process") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter breakdown") -AnnotationAssertion( "neurotransmitter catabolism") -AnnotationAssertion( "neurotransmitter degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042135") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter catabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (neurotransmitter biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter biosynthesis and storage") -AnnotationAssertion( "neurotransmitter biosynthetic process and storage") -AnnotationAssertion( "neurotransmitter anabolism") -AnnotationAssertion( "neurotransmitter biosynthesis") -AnnotationAssertion( "neurotransmitter formation") -AnnotationAssertion( "neurotransmitter synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042136") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter biosynthetic process") -SubClassOf( ) -SubClassOf( ) - # Class: (lipoprotein metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.") @@ -80149,15 +79761,6 @@ AnnotationAssertion( "lipoprotein catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (neurotransmitter binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042165") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter binding") -SubClassOf( ) - # Class: (acetylcholine binding) AnnotationAssertion(Annotation( "GOC:ai") "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") @@ -80165,7 +79768,6 @@ AnnotationAssertion( "GO:0042166") AnnotationAssertion(rdfs:label "acetylcholine binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (nuclear outer membrane-endoplasmic reticulum membrane network) @@ -81888,7 +81490,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ribonucleoprotein complex binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (ribosome binding) @@ -82404,8 +82005,8 @@ AnnotationAssertion(Annotation( "https://github.com/geneontology/go-ontology/issues/21881"^^xsd:anyURI) AnnotationAssertion( "NIF_Subcellular:sao1456184038") AnnotationAssertion( "non-membrane-enclosed organelle") -AnnotationAssertion( "biological condensate") AnnotationAssertion( "cellular_component") +AnnotationAssertion( "biological condensate") AnnotationAssertion( "GO:0043228") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "non-membrane-bounded organelle") @@ -82596,15 +82197,16 @@ AnnotationAssertion( "response to alkaloid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (pharyngeal muscle development) +# Class: (chordate pharyngeal muscle development) AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043282") -AnnotationAssertion(rdfs:label "pharyngeal muscle development") +AnnotationAssertion(rdfs:label "chordate pharyngeal muscle development") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (contractile fiber) @@ -82649,7 +82251,6 @@ AnnotationAssertion( "leukocyte degranulation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -82703,9 +82304,8 @@ AnnotationAssertion( "GO:0043312") AnnotationAssertion(rdfs:label "neutrophil degranulation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) # Class: (regulation of neutrophil degranulation) @@ -83412,8 +83012,8 @@ EquivalentClasses( ObjectIntersection # Class: (ossification involved in bone remodeling) AnnotationAssertion(Annotation( "GOC:mtg_mpo") Annotation( "GO_REF:0000034") "The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.") +AnnotationAssertion( "ossification involved in bone remodelling") AnnotationAssertion( "biological_process") -AnnotationAssertion( "ossification involved in bone remodelling") AnnotationAssertion( "GO:0043932") AnnotationAssertion(rdfs:label "ossification involved in bone remodeling") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -83790,20 +83390,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (dentate gyrus mossy fiber) - -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_20090601") Annotation( "PMID:17765709") "Distinctive, unmyelinated axons produced by dentate gyrus granule cells.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-02-05T11:23:55Z") -AnnotationAssertion( "granule cell axon") -AnnotationAssertion( "NIF_Subcellular:nlx_subcell_20090601") -AnnotationAssertion( "dentate gyrus mossy fibre") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0044302") -AnnotationAssertion(rdfs:label "dentate gyrus mossy fiber") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (type B pancreatic cell proliferation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:yaf") "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.") @@ -88305,6 +87891,7 @@ SubClassOf( (regulation of bone remodeling) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.") +AnnotationAssertion( "regulation of bone remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046850") AnnotationAssertion(rdfs:label "regulation of bone remodeling") @@ -88316,6 +87903,7 @@ AnnotationAssertion(Annotation( "down regulation of bone remodeling") AnnotationAssertion( "down-regulation of bone remodeling") AnnotationAssertion( "downregulation of bone remodeling") +AnnotationAssertion( "negative regulation of bone remodelling") AnnotationAssertion( "inhibition of bone remodeling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046851") @@ -88325,6 +87913,7 @@ EquivalentClasses( ObjectIntersection # Class: (positive regulation of bone remodeling) AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of bone remodeling.") +AnnotationAssertion( "positive regulation of bone remodelling") AnnotationAssertion( "up regulation of bone remodeling") AnnotationAssertion( "up-regulation of bone remodeling") AnnotationAssertion( "upregulation of bone remodeling") @@ -89332,13 +88921,13 @@ SubClassOf( (animal organ development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25943"^^xsd:anyURI) AnnotationAssertion( "Wikipedia:Organogenesis") AnnotationAssertion( "development of an organ") AnnotationAssertion( "organogenesis") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048513") AnnotationAssertion(rdfs:label "animal organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (blood vessel morphogenesis) @@ -89589,16 +89178,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (post-embryonic animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048563") -AnnotationAssertion(rdfs:label "post-embryonic animal organ morphogenesis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (digestive tract development) AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.") @@ -89625,16 +89204,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (post-embryonic animal organ development) - -AnnotationAssertion(Annotation( "GOC:jid") "Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "post-embryonic animal organogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048569") -AnnotationAssertion(rdfs:label "post-embryonic animal organ development") -SubClassOf( ) -SubClassOf( ) - # Class: (notochord morphogenesis) AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.") @@ -90495,6 +90064,7 @@ SubClassOf( (tissue remodeling) AnnotationAssertion(Annotation( "GOC:ebc") "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.") +AnnotationAssertion( "tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048771") AnnotationAssertion( ) @@ -92186,6 +91756,19 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ) +# Class: (ice binding) + +AnnotationAssertion(Annotation( "GOC:curators") "Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.") +AnnotationAssertion( "ice crystal binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "antifreeze activity") +AnnotationAssertion( "ice nucleation activity") +AnnotationAssertion( "ice nucleation inhibitor activity") +AnnotationAssertion( "GO:0050825") +AnnotationAssertion(rdfs:label "ice binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (defense response to fungus) AnnotationAssertion(Annotation( "GOC:ai") "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.") @@ -93093,7 +92676,7 @@ AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0050997") AnnotationAssertion(rdfs:label "quaternary ammonium group binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (actin filament bundle assembly) @@ -93819,9 +93402,11 @@ SubClassOf( (establishment of localization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI) AnnotationAssertion(Annotation( "GOC:mah") "establishment of localisation") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051234") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -104122,7 +103707,6 @@ AnnotationAssertion( "GO:0070051") AnnotationAssertion(rdfs:label "fibrinogen binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (extracellular exosome) @@ -111474,14 +111058,15 @@ SubClassOf( (hippocampal mossy fiber) -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_100312") Annotation( "PMID:17765709") "Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.") +AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_100312") Annotation( "PMID:17765709") Annotation( "PMID:20554881") Annotation( "PMID:24336151") "An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25796"^^xsd:anyURI) AnnotationAssertion( "pr") AnnotationAssertion( "2012-12-19T16:51:57Z") AnnotationAssertion( "NIF_Subcellular:nlx_subcell_100312") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0097457") AnnotationAssertion(rdfs:label "hippocampal mossy fiber") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (retinal rod cell apoptotic process) @@ -112017,7 +111602,6 @@ AnnotationAssertion( "GO:0098633") AnnotationAssertion(rdfs:label "collagen fibril binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (protein complex involved in cell-cell adhesion) @@ -113973,44 +113557,48 @@ AnnotationAssertion( "positive regulation of cardiac muscle myoblast proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (pharynx morphogenesis) +# Class: (nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "The process in which the anatomical structures of the pharynx are generated and organized.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "The process in which the anatomical structures of the nematode pharynx are generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T20:51:28Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110040") -AnnotationAssertion(rdfs:label "pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +AnnotationAssertion(rdfs:label "nematode pharynx morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (regulation of pharynx morphogenesis) +# Class: (regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that modulates the frequency, rate or extent of nematode pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:00:20Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110041") -AnnotationAssertion(rdfs:label "regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (negative regulation of pharynx morphogenesis) +# Class: (negative regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that stops, prevents, or reduces the frequency, rate or extent of nematode pharynx morphogenesis.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:05:08Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110042") -AnnotationAssertion(rdfs:label "negative regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "negative regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (positive regulation of pharynx morphogenesis) +# Class: (positive regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:09:48Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110043") -AnnotationAssertion(rdfs:label "positive regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "positive regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of actin filament organization) @@ -114321,10 +113909,12 @@ EquivalentClasses( ObjectIntersection # Class: (cellular anatomical entity) AnnotationAssertion(Annotation( "GOC:kmv") "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2019-08-12T18:01:37Z") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0110165") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular anatomical entity") SubClassOf( ) @@ -115309,6 +114899,7 @@ AnnotationAssertion(Annotation( "https://github.com/geneontology/go-ontology/issues/17073"^^xsd:anyURI) AnnotationAssertion( "pg") AnnotationAssertion( "2019-04-01T10:41:38Z") +AnnotationAssertion(Annotation(rdfs:label "M6PR transports activated ARSA to the lysosome") "Reactome:R-HSA-2248891") AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17 from ER to the Golgi-network") "Reactome:R-HSA-9662747") AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane") "Reactome:R-HSA-9662818") AnnotationAssertion( "molecular_function") @@ -115843,6 +115434,39 @@ AnnotationAssertion( "craniofacial suture closure") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (chordate pharynx development) + +AnnotationAssertion(Annotation( "PMID:23020903") "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T21:05:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160093") +AnnotationAssertion(rdfs:label "chordate pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nematode pharynx development) + +AnnotationAssertion(Annotation( "PMID:18050503") "The process whose specific outcome is the progression of nematode pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T22:05:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160094") +AnnotationAssertion(rdfs:label "nematode pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (insect pharynx development) + +AnnotationAssertion(Annotation( "PMID:10952900") "The process whose specific outcome is the progression of insect pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T22:14:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160095") +AnnotationAssertion(rdfs:label "insect pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of dendrite development) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of dendrite development.") @@ -118489,7 +118113,7 @@ AnnotationAssertion( AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:1901363") AnnotationAssertion(rdfs:label "heterocyclic compound binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (acetate ester transport) @@ -133204,18 +132828,6 @@ AnnotationAssertion(rdfs:label "posi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -# Class: (pharyngeal gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000083") Annotation( "PMID:21868609") "The developmental process by which a pharyngeal gland is generated and organized.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-03T14:39:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pharynx gland morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandulae pharyngeae morphogenesis") -AnnotationAssertion( "GO:1905905") -AnnotationAssertion(rdfs:label "pharyngeal gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of calcium ion export across plasma membrane) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.") @@ -143434,7 +143046,6 @@ AnnotationAssertion( "quality") AnnotationAssertion( "PATO:0000001") AnnotationAssertion(rdfs:label "quality") -SubClassOf( ) # Class: (color) @@ -144049,6 +143660,16 @@ AnnotationAssertion( "haploid") SubClassOf( ) +# Class: (polyploid) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Polyploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001377") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polyploid") +SubClassOf( ) + # Class: (euploid) AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Euploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes.") diff --git a/src/ontology/uberon-odk.yaml b/src/ontology/uberon-odk.yaml index 74fe8513f7..678988466d 100644 --- a/src/ontology/uberon-odk.yaml +++ b/src/ontology/uberon-odk.yaml @@ -44,7 +44,8 @@ import_group: - id: cl use_base: TRUE - id: go - use_base: TRUE + make_base: TRUE + mirror_from: http://purl.obolibrary.org/obo/go/go-base.owl base_iris: - http://purl.obolibrary.org/obo/GO_ - http://purl.obolibrary.org/obo/GOREL_