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Nicholas Brazeau
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Sep 19, 2024
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test_that("inheritnance of COI monoclonal", { | ||
# per the original model, we first consider the "deme" (host) and then draw parents | ||
# prior to allowing new progeny to migrate | ||
# Host.cpp line 50 | ||
# As a result, in instances where we force the COI to be 1, we should always | ||
# draw from the same "parent" strain within the host. Recombination will | ||
# thus occur but it will be undetected from a coalescence POV | ||
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### Magic Numbers | ||
rep <- 1:2 | ||
tlim <- 10 | ||
rho <- 7.4e-7 | ||
pflen <- 1.664e6 | ||
pos <- list(sort(sample(pflen, 1e3))) | ||
mean_coi <- 1.666424e-07 # force COI=1 | ||
N <- 5 | ||
m <- 0.5 | ||
#............................................................ | ||
# run for basic model | ||
#........................................................... | ||
migr_mat <- 1 | ||
snglmt <- tidyr::expand_grid(rep, pos, N, m, mean_coi, rho, tlim, migr_mat) | ||
snglmt$swfsim <- purrr::pmap(snglmt[2:ncol(snglmt)], polySimIBD::sim_swf) | ||
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#............................................................ | ||
# now with migration matrix | ||
#........................................................... | ||
migr_mat <- matrix(data = 0, nrow = 3, ncol = 3) | ||
diag(migr_mat) <- 1 | ||
# lift over prev sims | ||
dblmt <- tidyr::expand_grid(rep, pos, N, m, mean_coi, rho, tlim) | ||
dblmt <- dblmt %>% | ||
dplyr::mutate(N = purrr::map(N, function(x) rep(x,3)), | ||
m = purrr::map(m, function(x) rep(x,3)), | ||
mean_coi = purrr::map(mean_coi, function(x) rep(x,3))) | ||
dblmt <- dblmt %>% | ||
dplyr::mutate(migr_mat = purrr::map(rep, function(x) return(migr_mat))) | ||
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dblmt$swfsim <- purrr::pmap(dblmt[,2:ncol(dblmt)], polySimIBD::sim_swf) | ||
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#............................................................ | ||
# now compare/test that parents are always the same in original model | ||
# and more complex spatial structure model | ||
#........................................................... | ||
testthat::expect_equal(dblmt$swfsim[[1]]$parent_host1[[4]][[1]], | ||
dblmt$swfsim[[1]]$parent_host2[[4]][[1]]) # ind 1 gen 4 | ||
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testthat::expect_equal(dblmt$swfsim[[2]]$parent_host1[[8]][[2]], | ||
dblmt$swfsim[[2]]$parent_host2[[8]][[2]]) # ind 2 gen 8 | ||
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testthat::expect_equal(snglmt$swfsim[[1]]$parent_host1[[7]][[3]], | ||
snglmt$swfsim[[1]]$parent_host2[[7]][[3]]) # ind 3 gen 7 | ||
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}) |