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Merge pull request #7 from moka-guys/v1.3.0
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V1.3.0 (#7)
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RachelDuffin authored Dec 8, 2023
2 parents d980b10 + 71d8b2d commit 169855c
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6 changes: 3 additions & 3 deletions README.md
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# dnanexus_ED_readcount_analysis_v1.2.0
# dnanexus_ED_readcount_analysis_v1.3.0
Exome depth is run in two stages. Firstly, read counts are calculated, before CNVs are called using the read counts. Read counts are calculated over the entire genome whereas the CNV calling can be performed using a subpanel.

dnanexus_ED_readcount_analysis_v1.2.0 calculates readcounts for samples using panel of normals and intrabatch samples as reference.
dnanexus_ED_readcount_analysis_v1.3.0 calculates readcounts for samples using panel of normals and intrabatch samples as reference.

# What does the app do?
This app runs the read count calculation stage.

Using the provided DNANexus project and the list of Pan numbers the app downloads BAMs and BAI.

A Docker image containing Exome depth is downloaded from 001 - The Exomedepth image taken from https://github.com/moka-guys/seglh-cnv/releases/tag/v2.0.0
A Docker image containing Exome depth is downloaded from 001 - The Exomedepth image taken from https://github.com/moka-guys/seglh-cnv/releases/tag/v2.1.0

The `readCount.R` script is then called, producing a readcount file (`PanXXXXexomedepth_readCount.RData`) which can be used as an input for the ED_cnv_calling app https://github.com/moka-guys/dnanexus_ED_cnv_calling

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8 changes: 4 additions & 4 deletions dxapp.json
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{
"name": "ED_readcount_analysis_v1.2.0",
"title": "ED_readcount_analysis_v1.2.0",
"summary": "v1.2.0 - Step 1 of CNV calling using ExomeDepth",
"name": "ED_readcount_analysis_v1.3.0",
"title": "ED_readcount_analysis_v1.3.0",
"summary": "v1.3.0 - Step 1 of CNV calling using ExomeDepth",
"properties": {
"github release": "v1.2.0"
"github release": "v1.3.0"
},
"dxapi": "1.0.0",
"inputSpec": [
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4 changes: 2 additions & 2 deletions src/code.sh
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#!/bin/bash
# exomedepth_cnv_analysis_v1.2.0
# exomedepth_cnv_analysis_v1.3.0

# The following line causes bash to exit at any point if there is any error
# and to output each line as it is executed -- useful for debugging
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mark-section "setting up Exomedepth docker image"
# Location of the ExomeDepth docker file
docker_file_id=project-ByfFPz00jy1fk6PjpZ95F27J:file-GYzKz400jy1yx101F34p8qj2
docker_file_id=project-ByfFPz00jy1fk6PjpZ95F27J:file-Gbjy9yj0JQXkKB8bfFz856V6
# download the docker file from 001_Tools...
dx download $docker_file_id --auth "${API_KEY}"
docker_file=$(dx describe ${docker_file_id} --name)
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