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rcalef committed Nov 26, 2024
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<div class="columns is-centered">
<div class="column has-text-centered">
<img src="static/images/ProTeus-02-cropped.png" alt="ProTeus banner" style="height: 20%; width: auto;">
<h1 class="title is-1 publication-title"> Cross-Knowledge Foundation AI for Human Proteins</h1>
<h1 class="title is-1 publication-title">A foundation model for human protein phenotypes</h1>
<div class="is-size-5 publication-authors">
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<span class="author-block">
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<a href="THIRD AUTHOR PERSONAL LINK" target="_blank">Vikram Khurana</a><sup>8,9,11</sup>,
</span>
<span class="author-block">
<a href="THIRD AUTHOR PERSONAL LINK" target="_blank">Manolis Kellis</a><sup>2,11</sup>,
<a href="https://compbio.mit.edu/" target="_blank">Manolis Kellis</a><sup>2,11</sup>,
</span>
<span class="author-block">
<a href="THIRD AUTHOR PERSONAL LINK" target="_blank">Marinka Zitnik</a><sup>1,10,11,12,&Dagger;</sup>,
<a href="https://zitniklab.hms.harvard.edu/" target="_blank">Marinka Zitnik</a><sup>1,10,11,12,&Dagger;</sup>,
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<div class="hero-body">
<img src="static/images/model_use_cases.png" alt="ProTeus capabilities" style=" width: auto;">
<h2 class="subtitle has-text-centered">
We present ProTeus, a cross-knowledge foundation model for human proteins that co-trains a large language model with protein sequence and structure models.
We present <strong>ProTeus, a cross-knowledge foundation model for human proteins</strong> that co-trains a large language model with protein sequence and structure models.
ProTeus processes interleaved text and protein data, enabling zero-shot protein annotation prediction, phenotype generation, protein retrieval given text,
and zero-shot task generalization
</h2>
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