diff --git a/requirements.txt b/requirements.txt
index 0b1b601..9974dfc 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -5,5 +5,5 @@ psutil==5.9.5
 meeko==0.5.0
 rdkit==2023.3.2
 pdb2pqr==3.6.1
-PySide6-Essentials==6.5.2
+PySide6-Essentials==6.4.3
 pyinstaller==5.13.2