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R script for the comparison of fecal microRNA expression between 2 groups of children with bacterial and viral gastroenteritis.

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kagningemma/microRNA-differential-expression

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Aim

The Aim of this study was to compare microRNA differential expression in fecal samples of children with viral and bacterial gastroenteritis. I used Luminex xTAG device and kit for multiplex detection of pathogenic gastrointestinal bacteria and viruses.
Sapovirus was detected using qPCR.

Method

Total RNA was extracted from samples and I used microarrays to measure condition-wise microRNA expression signal. Data was analyzed using R. Objective 1: compare microRNA level between children with norovirus diarrhea Vs rotavirus diarrhea Objective 2: compare microRNA level between children with bacterial diarrhea Vs viral diarrhea.

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R script for the comparison of fecal microRNA expression between 2 groups of children with bacterial and viral gastroenteritis.

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