Xolik

Finding cross-linked peptides with maximum paired scores in linear time

Usage

Please ensure that the following packages exist.

• Python 2.7
• pandas

To run Xolik, use the following commands.

./Xolik -d db-filename.fasta -s msdata-filename.mzXML -o output-filename.csv --ms1tol 5 --ms2tol 0.02
python splitctrl.py output-filename.csv

Use ./Xolik --help for all available options.

The "Score" field in the result files equals to -log10(e-value) by default, and equals to XCorr if --noevalue is set.

Dependencies

• TCLAP
• GoogleTest (optional)

Publications

J. Dai*, W. Jiang*, F. Yu* and W. Yu, "Xolik: finding cross-linked peptides with maximum paired scores in linear time", in preparation. *Contributed equally to this work.

License

BSD License