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While working on gapseq I found that some pathways have key-reactions assigned, which are not in the reaction list (reaId column) of the pathway (see below). I checked the reactions and basically they are aliases or subreaction from the reaction list in the pathway. However, I am a little unsure how to handle them in the rewrite, as I thought about simply adding them to the reaction list, yet, this would increase the number of reactions in the pathway consequently leading to a dilution of the threshold for pathway completeness. If you have an opinion on that let me know.
Best,
Jan
While working on gapseq I found that some pathways have key-reactions assigned, which are not in the reaction list (reaId column) of the pathway (see below). I checked the reactions and basically they are aliases or subreaction from the reaction list in the pathway. However, I am a little unsure how to handle them in the rewrite, as I thought about simply adding them to the reaction list, yet, this would increase the number of reactions in the pathway consequently leading to a dilution of the threshold for pathway completeness. If you have an opinion on that let me know.
Best,
Jan
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