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Missing key reactions in reactions list of pathway #245

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Porthmeus opened this issue Dec 3, 2024 · 0 comments
Open

Missing key reactions in reactions list of pathway #245

Porthmeus opened this issue Dec 3, 2024 · 0 comments

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@Porthmeus
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Porthmeus commented Dec 3, 2024

While working on gapseq I found that some pathways have key-reactions assigned, which are not in the reaction list (reaId column) of the pathway (see below). I checked the reactions and basically they are aliases or subreaction from the reaction list in the pathway. However, I am a little unsure how to handle them in the rewrite, as I thought about simply adding them to the reaction list, yet, this would increase the number of reactions in the pathway consequently leading to a dilution of the threshold for pathway completeness. If you have an opinion on that let me know.
Best,
Jan

                       id        keyRea
                   <char>        <char>
1:             |PWY-4202|     RXN-21028
2:             |PWY-4202| 2.1.1.137-RXN
3:             |PWY-4202|     RXN-22330
4:             |PWY-8266|     RXN-21028
5:             |PWY-8266| 2.1.1.137-RXN
6:             |PWY-8266|     RXN-22330
7:             |PWY-8352|  1.4.1.21-RXN
8: INULIN-DEGRADATION-EXO     3.2.1.153
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