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To introduce new variable COVass_vpc designating assembled virus amount in vPC and implement release of COV from vPC from the variable. Delete release of the virus from COV_vpc.
Cell death leads to release of the virus bound with ACE2 at the cell surface. ACE2 is degraded.
To introduce 2 modes of immune response in empiric way: (i) Spike specific antibodies ( IgG/IgM) interfere binding of virus ACE2 (ii) stimulation of death of infected cells
Introduction of sputum dilution coefficient
Change in parameters k_rep_cov_rna_vpc , k_ass_cov_vpc , kbase_tran_pc_ipc , kbase_tran_ipc_vpc to describe clinically measured data on viral load and percent of subgenomic viral mRNA in sputum