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fadilla-wahyudi edited this page May 3, 2021
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This stand-alone program implements the Fine-Mapping of Adaptive Variation (FineMAV) statistic for detection of positively selected variants.
The FineMAV score of the derived allele for each SNP is calculated by multiplying three metrics:
- Derived allele purity -- measure of population differentiation that ranges from 0 to 1, where a score of 1 indicates that all the derived alelles fall into a single population.
- Derived allele frequency
- The Combined Annotation-Dependent Depletion PHRED-scaled C-score (CADD_PHRED) -- a measure of functionality