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@book{abbasbasic_2017,
title = {Le Basi Dell'immunologia : {{Fisiopatologia}} Del Sistema Immunitario},
author = {Abbas, Abul},
date = {2017},
publisher = {{Edra}},
location = {{Milano}},
isbn = {88-214-4255-1},
note = {Libro di Immunologia usato per preparare l'esame}
}
@article{austinEffectHighFlow2010,
title = {Effect of High Flow Oxygen on Mortality in Chronic Obstructive Pulmonary Disease Patients in Prehospital Setting: Randomised Controlled Trial},
shorttitle = {Effect of High Flow Oxygen on Mortality in Chronic Obstructive Pulmonary Disease Patients in Prehospital Setting},
author = {Austin, M. A. and Wills, K. E. and Blizzard, L. and Walters, E. H. and Wood-Baker, R.},
date = {2010-10-18},
journaltitle = {BMJ},
shortjournal = {BMJ},
volume = {341},
pages = {c5462-c5462},
issn = {0959-8138, 1468-5833},
doi = {10.1136/bmj.c5462},
url = {https://www.bmj.com/lookup/doi/10.1136/bmj.c5462},
urldate = {2022-07-18},
issue = {oct18 2},
langid = {english},
file = {/Users/vic/Zotero/storage/SLGYZAAA/Austin et al. - 2010 - Effect of high flow oxygen on mortality in chronic.pdf}
}
@article{benedetti-1995,
author = {al. F. Benedetti, et},
options = {useprefix=true},
date = {1995},
journaltitle = {Lancet Neurology},
shortjournal = {Lancet Neurol.},
number = {346}
}
@article{benedetti-2013,
author = {al. F. Benedetti, et},
options = {useprefix=true},
date = {2013},
journaltitle = {Phisiology Review}
}
@article{benedetti2006,
title = {Loss of Expectation-Related Mechanism in {{Alzheimer}}'s Disease Makes Analgesic Therapies Less Effective},
author = {al. F. Benedetti, et},
options = {useprefix=true},
date = {2006},
journaltitle = {Pain}
}
@article{benedetti2008,
author = {al. F. Benedetti, et},
options = {useprefix=true},
date = {2008},
journaltitle = {Ann. Rev. of Pharmacology and Toxicology}
}
@article{bodenheimerImprovingPrimaryCare2002,
title = {Improving {{Primary Care}} for {{Patients With Chronic Illness}}},
author = {Bodenheimer, Thomas and Wagner, Edward H. and Grumbach, Kevin},
date = {2002-10-09},
journaltitle = {JAMA : the journal of the American Medical Association},
shortjournal = {JAMA},
volume = {288},
number = {14},
pages = {1775--1779},
issn = {0098-7484},
doi = {10.1001/jama.288.14.1775},
url = {https://doi.org/10.1001/jama.288.14.1775},
urldate = {2021-05-20},
abstract = {The chronic care model is a guide to higher-quality chronic illness management within primary care. The model predicts that improvement in its 6 interrelated components—self-management support, clinical information systems, delivery system redesign, decision support, health care organization, and community resources—can produce system reform in which informed, activated patients interact with prepared, proactive practice teams. Case studies are provided describing how components of the chronic care model have been implemented in the primary care practices of 4 health care organizations.}
}
@article{brignole2018ESCGuidelines2018,
title = {2018 {{ESC Guidelines}} for the Diagnosis and Management of Syncope},
author = {Brignole, Michele and Moya, Angel and de Lange, Frederik J and Deharo, Jean-Claude and Elliott, Perry M and Fanciulli, Alessandra and Fedorowski, Artur and Furlan, Raffaello and Kenny, Rose Anne and Martín, Alfonso and Probst, Vincent and Reed, Matthew J and Rice, Ciara P and Sutton, Richard and Ungar, Andrea and van Dijk, J Gert and {ESC Scientific Document Group} and Torbicki, Adam and Moreno, Javier and Aboyans, Victor and Agewall, Stefan and Asteggiano, Riccardo and Blanc, Jean-Jacques and Bornstein, Natan and Boveda, Serge and Bueno, Héctor and Burri, Haran and Coca, Antonio and Collet, Jean-Philippe and Costantino, Giorgio and Díaz-Infante, Ernesto and Delgado, Victoria and Dolmans, Faas and Gaemperli, Oliver and Gajek, Jacek and Hindricks, Gerhard and Kautzner, Josef and Knuuti, Juhani and Kulakowski, Piotr and Lambrinou, Ekaterini and Leclercq, Christophe and Mabo, Philippe and Morillo, Carlos A and Piepoli, Massimo Francesco and Roffi, Marco and Shen, Win K and Simpson, Iain A and Stockburger, Martin and Vanbrabant, Peter and Windecker, Stephan and Zamorano, Jose Luis and Windecker, Stephan and Aboyans, Victor and Agewall, Stefan and Barbato, Emanuele and Bueno, Héctor and Coca, Antonio and Collet, Jean-Philippe and Coman, Ioan Mircea and Dean, Veronica and Delgado, Victoria and Fitzsimons, Donna and Gaemperli, Oliver and Hindricks, Gerhard and Iung, Bernard and Jüni, Peter and Katus, Hugo Albert and Knuuti, Juhani and Lancellotti, Patrizio and Leclercq, Christophe and McDonagh, Theresa and Piepoli, Massimo Francesco and Ponikowski, Piotr and Richter, Dimitrios J and Roffi, Marco and Shlyakhto, Evgeny and Sousa-Uva, Miguel and Simpson, Iain A and Zamorano, Jose Luis and Roithinger, Franz Xaver and Chasnoits, Alexandr and Vandekerckhove, Yves and Traykov, Vasil B and Puljevic, Davor and Papasavvas, Elias and Kautzner, Josef and Mølgaard, Henning and Nawar, Mostafa and Parikka, Hannu and Vavlukis, Marija and Piot, Olivier and Etsadashvili, Kakhaber and Klingenheben, Thomas and Deftereos, Spyridon and Sághy, László and Gudmundsson, Kristjan and Beinart, Roy and Raviele, Antonio and Abdrakhmanov, Ayan and Mirrakhimov, Erkin and Kalejs, Oskars and Benlamin, Hisham A and Puodziukynas, Aras and Dimmer, Carlo and Sammut, Mark A and Raducan, Aurica and Vukmirović, Mihailo and Abdelali, Salima and Hemels, Martin E W and Haugaa, Kristina H and Baranowski, Rafał and Cunha, Pedro Silva and Dan, Gheorghe-Andrei and Tyurina, Tatyana and Bertelli, Luca and Mitro, Peter and Lozano, Ignacio Fernández and Bergfeldt, Lennart and Osswald, Stefan and Afef, Ben Halima and Özdemír, H Murat and Lim, P Boon},
options = {useprefix=true},
date = {2018-06-01},
journaltitle = {European Heart Journal},
volume = {39},
number = {21},
pages = {1883--1948},
issn = {0195-668X, 1522-9645},
doi = {10.1093/eurheartj/ehy037},
url = {https://academic.oup.com/eurheartj/article/39/21/1883/4939241},
urldate = {2022-07-13},
langid = {english},
file = {/Users/vic/Zotero/storage/YHST8VUI/Brignole et al. - 2018 - 2018 ESC Guidelines for the diagnosis and manageme.pdf}
}
@article{chioncelEpidemiologyPathophysiologyContemporary2020,
title = {Epidemiology, Pathophysiology and Contemporary Management of Cardiogenic Shock – a Position Statement from the {{Heart Failure Association}} of the {{European Society}} of {{Cardiology}}},
author = {Chioncel, Ovidiu and Parissis, John and Mebazaa, Alexandre and Thiele, Holger and Desch, Steffen and Bauersachs, Johann and Harjola, Veli‐Pekka and Antohi, Elena‐Laura and Arrigo, Mattia and Gal, Tuvia B. and Celutkiene, Jelena and Collins, Sean P. and DeBacker, Daniel and Iliescu, Vlad A. and Jankowska, Ewa and Jaarsma, Tiny and Keramida, Kalliopi and Lainscak, Mitja and Lund, Lars H and Lyon, Alexander R. and Masip, Josep and Metra, Marco and Miro, Oscar and Mortara, Andrea and Mueller, Christian and Mullens, Wilfried and Nikolaou, Maria and Piepoli, Massimo and Price, Susana and Rosano, Giuseppe and Vieillard‐Baron, Antoine and Weinstein, Jean M. and Anker, Stefan D. and Filippatos, Gerasimos and Ruschitzka, Frank and Coats, Andrew J.S. and Seferovic, Petar},
date = {2020-08},
journaltitle = {European Journal of Heart Failure},
shortjournal = {Eur J Heart Fail},
volume = {22},
number = {8},
pages = {1315--1341},
issn = {1388-9842, 1879-0844},
doi = {10.1002/ejhf.1922},
url = {https://onlinelibrary.wiley.com/doi/10.1002/ejhf.1922},
urldate = {2022-07-14},
langid = {english},
file = {/Users/vic/Zotero/storage/B9ZGH3VA/Chioncel et al. - 2020 - Epidemiology, pathophysiology and contemporary man.pdf}
}
@article{comai_case_2019,
title = {A Case Report of {{IgG4-related}} Disease: {{An}} Insidious Path to the Diagnosis through Kidney, Heart and Brain},
shorttitle = {A Case Report of {{IgG4-related}} Disease},
author = {Comai, Giorgia and Cuna, Vania and Fabbrizio, Benedetta and Sabattini, Elena and Leone, Ornella and Tondolo, Francesco and Angeletti, Andrea and Cappuccilli, Maria and Liguori, Rocco and La Manna, Gaetano},
date = {2019-11-21},
journaltitle = {BMC nephrology},
shortjournal = {BMC Nephrol},
volume = {20},
number = {1},
eprint = {31752722},
eprinttype = {pmid},
pages = {418},
issn = {1471-2369},
doi = {10.1186/s12882-019-1587-4},
abstract = {BACKGROUND: IgG4-related disease, described around the years 2000 as a form of autoimmune pancreatitis, is now increasingly accepted as a systemic syndrome. The diagnosis is based on both comprehensive and organ-specific criteria. For the kidney, Mayo clinic classification and the guidelines of the Japanese Nephrology Society are used. Ultimately, together with parameters that characterize every organ or apparatus involved, the key element is the confirmation of growing levels of IgG4 in blood or in tissues. CASE PRESENTATION: We describe a male patient with chronic renal failure associated to hypertension without proteinuria. IgG4-related disease was diagnosed through renal biopsy. After an initial positive response to steroids, he presented tinnitus, and histological assessment showed cerebral and subsequently cardiac damage, both IgG4-related. This case appears unique for the type of histologically documented cardiac and neurological parenchymal involvement, and at the same time, exemplifies the subtle and pernicious course of the disease. Frequently, blurred and non-specific signs prevail. Here, kidney damage was associated with minimal urinary findings, slowly progressive renal dysfunction and other factors that can be equivocated in the differential diagnosis. Neurological involvement was represented by tinnitus alone, while cardiac alterations were completely asymptomatic. CONCLUSIONS: This report is representative of the neurological and cardiac changes described in the literature for IgG4-related disease, which may be correlated or not with the renal form and highlights the need, in some cases, of targeted therapeutic approaches. In addition to glucocorticoids, as in this case, rituximab may be necessary.},
langid = {english},
pmcid = {PMC6868811},
keywords = {B-lymphocytes,Biopsy,Brain,Chronic,Disease Progression,Glucocorticoids,Heart,Humans,Hypertension,IgG4-related disease,Immunoglobulin G,Immunoglobulin G4-Related Disease,Immunologic Factors,Kidney,Kidney Failure,Male,Methylprednisolone,Middle Aged,Myocardium,nefro,Nervous system,Rituximab,Symptom Assessment,T-lymphocytes,Tinnitus,Ultrasonography},
file = {/Users/vic/Zotero/storage/WFFMCMIF/Comai et al. - 2019 - A case report of IgG4-related disease An insidiou.pdf}
}
@article{DeclarationAlmaAtaInternational2004,
title = {Declaration of {{Alma-Ata International Conference}} on {{Primary Health Care}}, {{Alma-Ata}}, {{USSR}}, 6–12 {{September}} 1978},
date = {2004-06},
journaltitle = {Development (Cambridge, England)},
shortjournal = {Development},
volume = {47},
number = {2},
pages = {159--161},
issn = {1011-6370, 1461-7072},
doi = {10.1057/palgrave.development.1100047},
url = {http://link.springer.com/10.1057/palgrave.development.1100047},
urldate = {2021-05-20},
langid = {english}
}
@article{delucagiuseppeTimeDelayTreatment2004,
title = {Time {{Delay}} to {{Treatment}} and {{Mortality}} in {{Primary Angioplasty}} for {{Acute Myocardial Infarction}}},
author = {{De Luca Giuseppe} and {Suryapranata Harry} and {Ottervanger Jan Paul} and {Antman Elliott M.}},
date = {2004-03-16},
journaltitle = {Circulation},
shortjournal = {Circulation},
volume = {109},
number = {10},
pages = {1223--1225},
publisher = {{American Heart Association}},
doi = {10.1161/01.CIR.0000121424.76486.20},
url = {https://www.ahajournals.org/doi/10.1161/01.CIR.0000121424.76486.20},
urldate = {2021-04-14},
abstract = {Background— Although the relationship between mortality and time delay to treatment has been demonstrated in patients with acute ST-segment elevation myocardial infarction (STEMI) treated by thrombolysis, the impact of time delay on prognosis in patients undergoing primary angioplasty has yet to be clarified. The aim of this report was to address the relationship between time to treatment and mortality as a continuous function and to estimate the risk of mortality for each 30-minute delay.Methods and Results— The study population consisted of 1791 patients with STEMI treated by primary angioplasty. The relationship between ischemic time and 1-year mortality was assessed as a continuous function and plotted with a quadratic regression model. The Cox proportional hazards regression model was used to calculate relative risks (for each 30 minutes of delay), adjusted for baseline characteristics related to ischemic time. Variables related to time to treatment were age {$>$}70 years (P{$<$}0.0001), female gender (P=0.004), presence of diabetes mellitus (P=0.002), and previous revascularization (P=0.035). Patients with successful reperfusion had a significantly shorter ischemic time (P=0.006). A total of 103 patients (5.8\%) had died at 1-year follow-up. After adjustment for age, gender, diabetes, and previous revascularization, each 30 minutes of delay was associated with a relative risk for 1-year mortality of 1.075 (95\% CI 1.008 to 1.15; P=0.041).Conclusions— These results suggest that every minute of delay in primary angioplasty for STEMI affects 1-year mortality, even after adjustment for baseline characteristics. Therefore, all efforts should be made to shorten the total ischemic time, not only for thrombolytic therapy but also for primary angioplasty.},
file = {/Users/vic/Zotero/storage/TQTUSCEE/De Luca Giuseppe et al. - 2004 - Time Delay to Treatment and Mortality in Primary A.pdf}
}
@article{denisonCoronavirusesRNAProofreading2011,
title = {Coronaviruses - {{An RNA}} Proofreading Machine Regulates Replication Fidelity and Diversity},
author = {Denison, Mark R. and Graham, Rachel L. and Donaldson, Eric F. and Eckerle, Lance D. and Baric, Ralph S.},
date = {2011-03-01},
journaltitle = {RNA Biology},
shortjournal = {RNA Biol},
volume = {8},
number = {2},
eprint = {21593585},
eprinttype = {pmid},
pages = {270--279},
issn = {1547-6286},
doi = {10.4161/rna.8.2.15013},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127101/},
urldate = {2021-01-28},
abstract = {In order to survive and propagate, RNA viruses must achieve a balance between the capacity for adaptation to new environmental conditions or host cells with the need to maintain an intact and replication competent genome. Several virus families in the order Nidovirales, such as the coronaviruses (CoVs) must achieve these objectives with the largest and most complex replicating RNA genomes known, up to 32 kb of positive-sense RNA. The CoVs encode sixteen nonstructural proteins (nsp 1-16) with known or predicted RNA synthesis and modification activities, and it has been proposed that they are also responsible for the evolution of large genomes. The CoVs, including murine hepatitis virus (MHV) and SARS-CoV, encode a 3’-to-5’ exoribonuclease activity (ExoN) in nsp14. Genetic inactivation of ExoN activity in engineered SARS-CoV and MHV genomes by alanine substitution at conserved DE-D-D active site residues results in viable mutants that demonstrate 15- to 20-fold increases in mutation rates, up to 18 times greater than those tolerated for fidelity mutants of other RNA viruses. Thus nsp14-ExoN is essential for replication fidelity, and likely serves either as a direct mediator or regulator of a more complex RNA proofreading machine, a process previously unprecedented in RNA virus biology. Elucidation of the mechanisms of nsp14-mediated proofreading will have major implications for our understanding of the evolution of RNA viruses, and also will provide a robust model to investigate the balance between fidelity, diversity and pathogenesis. The discovery of a protein distinct from a viral RdRp that regulates replication fidelity also raises the possibility that RNA genome replication fidelity may be adaptable to differing replication environments and selective pressures, rather than being a fixed determinant.},
pmcid = {PMC3127101},
file = {/Users/vic/Zotero/storage/8MA3F5P6/Denison et al. - 2011 - Coronaviruses - An RNA proofreading machine regula.pdf}
}
@article{dhananiResumptionCardiacActivity2021a,
title = {Resumption of {{Cardiac Activity}} after {{Withdrawal}} of {{Life-Sustaining Measures}}},
author = {Dhanani, Sonny and Hornby, Laura and van Beinum, Amanda and Scales, Nathan B. and Hogue, Melanie and Baker, Andrew and Beed, Stephen and Boyd, J. Gordon and Chandler, Jennifer A. and Chassé, Michaël and D’Aragon, Frederick and Dezfulian, Cameron and Doig, Christopher J. and Duska, Frantisek and Friedrich, Jan O. and Gardiner, Dale and Gofton, Teneille and Harvey, Dan and Herry, Christophe and Isac, George and Kramer, Andreas H. and Kutsogiannis, Demetrios J. and Maslove, David M. and Meade, Maureen and Mehta, Sangeeta and Munshi, Laveena and Norton, Loretta and Pagliarello, Giuseppe and Ramsay, Tim and Rusinova, Katerina and Scales, Damon and Schmidt, Matous and Seely, Andrew and Shahin, Jason and Slessarev, Marat and So, Derek and Talbot, Heather and van Mook, Walther N.K.A. and Waldauf, Petr and Weiss, Matthew and Wind, Jentina T. and Shemie, Sam D.},
options = {useprefix=true},
date = {2021-01-28},
journaltitle = {New England Journal of Medicine},
volume = {384},
number = {4},
pages = {345--352},
publisher = {{Massachusetts Medical Society}},
issn = {0028-4793},
doi = {10.1056/NEJMoa2022713},
url = {https://doi.org/10.1056/NEJMoa2022713},
urldate = {2021-02-07},
keywords = {donazione-organi,morte},
note = {\_eprint: https://doi.org/10.1056/NEJMoa2022713},
file = {/Users/vic/Zotero/storage/DQLDVBK2/Dhanani et al. - 2021 - Resumption of Cardiac Activity after Withdrawal of.pdf}
}
@book{douglas2016macleod,
title = {Macleod : {{Manuale}} Di Semeiotica e Metodologia Medica},
author = {Douglas, Graham},
date = {2016},
publisher = {{EDRA}},
location = {{Milano}},
isbn = {88-214-3847-3}
}
@article{finnis2010,
author = {Finnis, Kaptchuk, Miller, Benedetti},
date = {2010},
journaltitle = {Lancet (London, England)},
shortjournal = {Lancet}
}
@article{galie2015ESCERS2016,
title = {2015 {{ESC}}/{{ERS Guidelines}} for the Diagnosis and Treatment of Pulmonary Hypertension: {{The Joint Task Force}} for the {{Diagnosis}} and {{Treatment}} of {{Pulmonary Hypertension}} of the {{European Society}} of {{Cardiology}} ({{ESC}}) and the {{European Respiratory Society}} ({{ERS}}): {{Endorsed}} by: {{Association}} for {{European Paediatric}} and {{Congenital Cardiology}} ({{AEPC}}), {{International Society}} for {{Heart}} and {{Lung Transplantation}} ({{ISHLT}})},
shorttitle = {2015 {{ESC}}/{{ERS Guidelines}} for the Diagnosis and Treatment of Pulmonary Hypertension},
author = {Galiè, Nazzareno and Humbert, Marc and Vachiery, Jean-Luc and Gibbs, Simon and Lang, Irene and Torbicki, Adam and Simonneau, Gérald and Peacock, Andrew and Vonk Noordegraaf, Anton and Beghetti, Maurice and Ghofrani, Ardeschir and Gomez Sanchez, Miguel Angel and Hansmann, Georg and Klepetko, Walter and Lancellotti, Patrizio and Matucci, Marco and McDonagh, Theresa and Pierard, Luc A. and Trindade, Pedro T. and Zompatori, Maurizio and Hoeper, Marius and {ESC Scientific Document Group}},
date = {2016-01-01},
journaltitle = {European Heart Journal},
shortjournal = {European Heart Journal},
volume = {37},
number = {1},
pages = {67--119},
issn = {0195-668X},
doi = {10.1093/eurheartj/ehv317},
url = {https://doi.org/10.1093/eurheartj/ehv317},
urldate = {2022-07-02},
file = {/Users/vic/Zotero/storage/DBKBFKTA/Galiè et al. - 2016 - 2015 ESCERS Guidelines for the diagnosis and trea.pdf}
}
@incollection{Garrido_2001,
title = {{{MHC}} Antigens and Tumor Escape from Immune Surveillance},
booktitle = {Advances in Cancer Research},
author = {Garrido, Federico and Algarra, Ignacio},
date = {2001},
pages = {117--158},
publisher = {{Elsevier}},
doi = {10.1016/s0065-230x(01)83005-0},
url = {https://doi.org/10.1016%2Fs0065-230x%2801%2983005-0}
}
@article{girardisEffectConservativeVs2016,
title = {Effect of {{Conservative}} vs {{Conventional Oxygen Therapy}} on {{Mortality Among Patients}} in an {{Intensive Care Unit}}: {{The Oxygen-ICU Randomized Clinical Trial}}},
shorttitle = {Effect of {{Conservative}} vs {{Conventional Oxygen Therapy}} on {{Mortality Among Patients}} in an {{Intensive Care Unit}}},
author = {Girardis, Massimo and Busani, Stefano and Damiani, Elisa and Donati, Abele and Rinaldi, Laura and Marudi, Andrea and Morelli, Andrea and Antonelli, Massimo and Singer, Mervyn},
date = {2016-10-18},
journaltitle = {JAMA},
shortjournal = {JAMA},
volume = {316},
number = {15},
pages = {1583},
issn = {0098-7484},
doi = {10.1001/jama.2016.11993},
url = {http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.2016.11993},
urldate = {2022-07-18},
langid = {english},
file = {/Users/vic/Zotero/storage/AH2E5VXJ/Girardis et al. - 2016 - Effect of Conservative vs Conventional Oxygen Ther.pdf}
}
@article{gracely-1985,
title = {Clinicians' Expectations Influcence Placebo Analgesia},
author = {al. R. Gracely, et},
options = {useprefix=true},
date = {1985},
journaltitle = {Lancet Medical Journal},
doi = {10.1016/S0140-6736(85)90984-5}
}
@book{gray2017anatomia,
title = {Anatomia Del {{Gray}}: {{Le}} Basi Anatomiche per La Pratica Clinica},
author = {Gray, Henry},
date = {2017},
publisher = {{Edra}},
location = {{Milano}},
isbn = {978-88-214-4147-9}
}
@article{huber_how_2011,
title = {How Should We Define Health?},
author = {Huber, Machteld and Knottnerus, J. André and Green, Lawrence and van der Horst, Henriëtte and Jadad, Alejandro R. and Kromhout, Daan and Leonard, Brian and Lorig, Kate and Loureiro, Maria Isabel and van der Meer, Jos W. M. and Schnabel, Paul and Smith, Richard and van Weel, Chris and Smid, Henk},
options = {useprefix=true},
date = {2011-07-26},
journaltitle = {BMJ (Clinical research ed.)},
shortjournal = {BMJ},
volume = {343},
eprint = {21791490},
eprinttype = {pmid},
pages = {d4163},
publisher = {{British Medical Journal Publishing Group}},
issn = {0959-8138, 1468-5833},
doi = {10.1136/bmj.d4163},
url = {https://www.bmj.com/content/343/bmj.d4163},
urldate = {2021-03-03},
abstract = {The WHO definition of health as complete wellbeing is no longer fit for purpose given the rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis towards the ability to adapt and self manage in the face of social, physical, and emotional challenges},
langid = {english},
keywords = {IGIENE},
file = {/Users/vic/Zotero/storage/M3P752IQ/Huber et al. - 2011 - How should we define health.pdf}
}
@article{konstantinides2019ESCGuidelines2020,
title = {2019 {{ESC Guidelines}} for the Diagnosis and Management of Acute Pulmonary Embolism Developed in Collaboration with the {{European Respiratory Society}} ({{ERS}}): {{The Task Force}} for the Diagnosis and Management of Acute Pulmonary Embolism of the {{European Society}} of {{Cardiology}} ({{ESC}})},
shorttitle = {2019 {{ESC Guidelines}} for the Diagnosis and Management of Acute Pulmonary Embolism Developed in Collaboration with the {{European Respiratory Society}} ({{ERS}})},
author = {Konstantinides, Stavros V and Meyer, Guy and Becattini, Cecilia and Bueno, Héctor and Geersing, Geert-Jan and Harjola, Veli-Pekka and Huisman, Menno V and Humbert, Marc and Jennings, Catriona Sian and Jiménez, David and Kucher, Nils and Lang, Irene Marthe and Lankeit, Mareike and Lorusso, Roberto and Mazzolai, Lucia and Meneveau, Nicolas and Ní Áinle, Fionnuala and Prandoni, Paolo and Pruszczyk, Piotr and Righini, Marc and Torbicki, Adam and Van Belle, Eric and Zamorano, José Luis and {ESC Scientific Document Group}},
date = {2020-01-21},
journaltitle = {European Heart Journal},
shortjournal = {European Heart Journal},
volume = {41},
number = {4},
pages = {543--603},
issn = {0195-668X},
doi = {10.1093/eurheartj/ehz405},
url = {https://doi.org/10.1093/eurheartj/ehz405},
urldate = {2022-07-01},
abstract = {For the Supplementary Data which include background information and detailed discussion of the data that have provided the basis for the Guidelines see https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehz405\#supplementary-data},
file = {/Users/vic/Zotero/storage/NS8RNXFP/Konstantinides et al. - 2020 - 2019 ESC Guidelines for the diagnosis and manageme.pdf;/Users/vic/Zotero/storage/VXNBSIIN/5556136.html}
}
@article{Kristinsson_2013,
title = {Long-Term Risks after Splenectomy among 8,149 Cancer-Free {{American}} Veterans: {{A}} Cohort Study with up to 27 Years Follow-Up},
author = {Kristinsson, S. Y. and Gridley, G. and Hoover, R. N. and Check, D. and Landgren, O.},
date = {2013-09},
journaltitle = {Haematologica},
volume = {99},
number = {2},
pages = {392--398},
publisher = {{Ferrata Storti Foundation (Haematologica)}},
doi = {10.3324/haematol.2013.092460},
url = {https://doi.org/10.3324%2Fhaematol.2013.092460},
abstract = {Although preservation of the spleen following abdominal trauma and spleen-preserving surgical procedures have become gold standards, about 22,000 splenectomies are still conducted annually in the USA. Infections, mostly by encapsulated organisms, are the most well-known complications following splenectomy. Recently, thrombosis and cancer have become recognized as potential adverse outcomes post-splenectomy. Among more than 4 million hospitalized USA veterans, we assessed incidence and mortality due to infections, thromboembolism, and cancer including 8,149 cancer-free veterans who underwent splenectomy with a follow-up of up to 27 years. Relative risk estimates and 95\% confidence intervals were calculated using time-dependent Poisson regression methods for cohort data. Splenectomized patients had an increased risk of being hospitalized for pneumonia, meningitis, and septicemia (rate ratios=1.9–3.4); deep venous thrombosis and pulmonary embolism (rate ratios=2.2); certain solid tumors: buccal, esophagus, liver, colon, pancreas, lung, and prostate (rate ratios =1.3–1.9); and hematologic malignancies: non-Hodgkin lymphoma, Hodgkin lymphoma, multiple myeloma, acute myeloid leukemia, chronic lymphocytic leukemia, chronic myeloid leukemia, and any leukemia (rate ratios =1.8–6.0). They also had an increased risk of death due to pneumonia and septicemia (rate ratios =1.6–3.0); pulmonary embolism and coronary artery disease (rate ratios =1.4–4.5); any cancer: liver, pancreas, and lung cancer, non-Hodgkin lymphoma, Hodgkin lymphoma, and any leukemia (rate ratios =1.3–4.7). Many of the observed risks were increased more than 10 years after splenectomy. Our results underscore the importance of vaccination, surveillance, and thromboprophylaxis after splenectomy.},
file = {/Users/vic/Zotero/storage/GKNF48R8/Kristinsson et al. - 2013 - Long-term risks after splenectomy among 8,149 canc.pdf}
}
@misc{macioccoTrasformazioniSistemiSanitari2002,
title = {Le Trasformazioni Dei Sistemi Sanitari: {{Un}} Itinerario Storico. {{Dal}} Liberismo al Liberismo, La Parabola Del Diritto Alla Salute Dall'{{Ottocento}} al {{Duemila}}},
shorttitle = {Le Trasformazioni Dei Sistemi Sanitari},
author = {Maciocco, Gavino},
date = {2002-10-25}
}
@article{marmot_covid-19_2020,
title = {{{COVID-19}}: {{Exposing}} and Amplifying Inequalities},
shorttitle = {{{COVID-19}}},
author = {Marmot, Michael and Allen, Jessica},
date = {2020-09},
journaltitle = {Journal of Epidemiology and Community Health},
shortjournal = {J Epidemiol Community Health},
volume = {74},
number = {9},
eprint = {32669357},
eprinttype = {pmid},
pages = {681--682},
issn = {0143-005X},
doi = {10.1136/jech-2020-214720},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577092/},
urldate = {2021-03-12},
pmcid = {PMC7577092},
keywords = {disuguaglianze,epidemiologia,IGIENE},
file = {/Users/vic/Zotero/storage/W2RDR2T6/Marmot and Allen - 2020 - COVID-19 Exposing and amplifying inequalities.pdf}
}
@article{medlife-placebo,
title = {How Medical Research Gets It Wrong (Medical Bias Part 1)},
author = {Francis, Rohin},
date = {2018},
url = {https://www.youtube.com/watch?v=ooWA4tM<sub>g</sub>Us}
}
@book{netter2014atlas,
title = {Atlante Di Anatomia Umana},
author = {Netter, Frank},
date = {2014},
publisher = {{Saunders/Elsevier}},
location = {{Philadelphia, PA}},
isbn = {978-1-4557-0418-7}
}
@book{netter2018atlas,
title = {Atlas of Human Anatomy},
author = {Netter, Frank},
date = {2018},
publisher = {{Elsevier}},
location = {{Philadelphia, PA}},
isbn = {978-0-323-39322-5}
}
@article{noauthor_sars_2003,
title = {{{SARS}}: {{What}} Have We Learned?},
shorttitle = {{{SARS}}},
date = {2003-07-01},
journaltitle = {Nature},
volume = {424},
number = {6945},
pages = {121--126},
publisher = {{Nature Publishing Group}},
issn = {1476-4687},
doi = {10.1038/424121a},
url = {https://www.nature.com/articles/424121a},
urldate = {2021-02-16},
abstract = {It's less than four months since the World Health Organization issued global warnings about a mysterious and deadly form of pneumonia. Nature's reporters pose key questions about the outbreak, and assess our preparedness to deal with future viral threats.},
langid = {english},
keywords = {microbiologia},
file = {/Users/vic/Zotero/storage/29BWWB73/2003 - SARS What have we learned.pdf}
}
@article{onesimo2012,
title = {Congenital Syphilis: {{Remember}} to Not Forget},
author = {Onesimo, Roberta and Buonsenso, Danilo and Gioè, Claudia and Valetini, Piero},
date = {2012},
journaltitle = {Case Reports},
volume = {2012},
eprint = {https://casereports.bmj.com/content/2012/bcr.01.2012.5597.full.pdf},
publisher = {{BMJ Publishing Group}},
doi = {10.1136/bcr.01.2012.5597},
url = {https://casereports.bmj.com/content/2012/bcr.01.2012.5597},
elocation-id = {bcr0120125597},
file = {/Users/vic/Zotero/storage/DCST36WA/Onesimo et al. - 2012 - Congenital syphilis Remember to not forget.pdf}
}
@article{rossouwRisksBenefitsEstrogen2002,
title = {Risks and Benefits of Estrogen plus Progestin in Healthy Postmenopausal Women: {{Principal}} Results {{From}} the {{Women}}'s {{Health Initiative}} Randomized Controlled Trial},
shorttitle = {Risks and Benefits of Estrogen plus Progestin in Healthy Postmenopausal Women},
author = {Rossouw, Jacques E. and Anderson, Garnet L. and Prentice, Ross L. and LaCroix, Andrea Z. and Kooperberg, Charles and Stefanick, Marcia L. and Jackson, Rebecca D. and Beresford, Shirley A. A. and Howard, Barbara V. and Johnson, Karen C. and Kotchen, Jane Morley and Ockene, Judith and {Writing Group for the Women's Health Initiative Investigators}},
date = {2002-07-17},
journaltitle = {JAMA : the journal of the American Medical Association},
shortjournal = {JAMA},
volume = {288},
number = {3},
eprint = {12117397},
eprinttype = {pmid},
pages = {321--333},
issn = {0098-7484},
doi = {10.1001/jama.288.3.321},
abstract = {CONTEXT: Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain. OBJECTIVE: To assess the major health benefits and risks of the most commonly used combined hormone preparation in the United States. DESIGN: Estrogen plus progestin component of the Women's Health Initiative, a randomized controlled primary prevention trial (planned duration, 8.5 years) in which 16608 postmenopausal women aged 50-79 years with an intact uterus at baseline were recruited by 40 US clinical centers in 1993-1998. INTERVENTIONS: Participants received conjugated equine estrogens, 0.625 mg/d, plus medroxyprogesterone acetate, 2.5 mg/d, in 1 tablet (n = 8506) or placebo (n = 8102). MAIN OUTCOMES MEASURES: The primary outcome was coronary heart disease (CHD) (nonfatal myocardial infarction and CHD death), with invasive breast cancer as the primary adverse outcome. A global index summarizing the balance of risks and benefits included the 2 primary outcomes plus stroke, pulmonary embolism (PE), endometrial cancer, colorectal cancer, hip fracture, and death due to other causes. RESULTS: On May 31, 2002, after a mean of 5.2 years of follow-up, the data and safety monitoring board recommended stopping the trial of estrogen plus progestin vs placebo because the test statistic for invasive breast cancer exceeded the stopping boundary for this adverse effect and the global index statistic supported risks exceeding benefits. This report includes data on the major clinical outcomes through April 30, 2002. Estimated hazard ratios (HRs) (nominal 95\% confidence intervals [CIs]) were as follows: CHD, 1.29 (1.02-1.63) with 286 cases; breast cancer, 1.26 (1.00-1.59) with 290 cases; stroke, 1.41 (1.07-1.85) with 212 cases; PE, 2.13 (1.39-3.25) with 101 cases; colorectal cancer, 0.63 (0.43-0.92) with 112 cases; endometrial cancer, 0.83 (0.47-1.47) with 47 cases; hip fracture, 0.66 (0.45-0.98) with 106 cases; and death due to other causes, 0.92 (0.74-1.14) with 331 cases. Corresponding HRs (nominal 95\% CIs) for composite outcomes were 1.22 (1.09-1.36) for total cardiovascular disease (arterial and venous disease), 1.03 (0.90-1.17) for total cancer, 0.76 (0.69-0.85) for combined fractures, 0.98 (0.82-1.18) for total mortality, and 1.15 (1.03-1.28) for the global index. Absolute excess risks per 10 000 person-years attributable to estrogen plus progestin were 7 more CHD events, 8 more strokes, 8 more PEs, and 8 more invasive breast cancers, while absolute risk reductions per 10 000 person-years were 6 fewer colorectal cancers and 5 fewer hip fractures. The absolute excess risk of events included in the global index was 19 per 10 000 person-years. CONCLUSIONS: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women. All-cause mortality was not affected during the trial. The risk-benefit profile found in this trial is not consistent with the requirements for a viable intervention for primary prevention of chronic diseases, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.},
langid = {english},
keywords = {Aged,Bone,Breast Neoplasms,Clinical Trials Data Monitoring Committees,Colorectal Neoplasms,Conjugated (USP),Coronary Disease,Endometrial Neoplasms,Estrogen Replacement Therapy,Estrogens,Female,Fractures,Humans,Medroxyprogesterone Acetate,Middle Aged,Myocardial Infarction,Postmenopause,Progesterone Congeners,Proportional Hazards Models,Pulmonary Embolism,Risk,Stroke,Survival Analysis,Thrombosis,Treatment Outcome},
file = {/Users/vic/Zotero/storage/R2GUWM8A/Rossouw et al. - 2002 - Risks and benefits of estrogen plus progestin in h.pdf}
}
@article{sgarbossaElectrocardiographicDiagnosisEvolving1996,
title = {Electrocardiographic {{Diagnosis}} of {{Evolving Acute Myocardial Infarction}} in the {{Presence}} of {{Left Bundle-Branch Block}}},
author = {Sgarbossa, Elena B. and Pinski, Sergio L. and Barbagelata, Alejandro and Underwood, Donald A. and Gates, Kathy B. and Topol, Eric J. and Califf, Robert M. and Wagner, Galen S.},
date = {1996-02-22},
journaltitle = {New England Journal of Medicine},
volume = {334},
number = {8},
eprint = {8559200},
eprinttype = {pmid},
pages = {481--487},
publisher = {{Massachusetts Medical Society}},
issn = {0028-4793},
doi = {10.1056/NEJM199602223340801},
url = {https://doi.org/10.1056/NEJM199602223340801},
urldate = {2021-05-12},
abstract = {The optimal use of coronary reperfusion therapies relies on a rapid diagnosis of evolving myocardial infarction.1,2 For most patients presenting with cardiac chest pain, the electrocardiogram is a powerful aid in diagnosing the cause of the pain and selecting the appropriate therapy.2 In patients who present with concomitant left bundle-branch block, however, the electrocardiographic manifestations of acute myocardial injury may be masked. During the past five decades, several electrocardiographic signs have been proposed to aid in the diagnosis of infarction in such patients, but because of methodologic limitations,3–9 none of these signs have gained widespread acceptance. Many physicians . . .},
keywords = {cardio},
note = {\_eprint: https://doi.org/10.1056/NEJM199602223340801},
file = {/Users/vic/Zotero/storage/K8FX75RP/Sgarbossa et al. - 1996 - Electrocardiographic Diagnosis of Evolving Acute M.pdf}
}
@article{siemieniukOxygenTherapyAcutely2018,
title = {Oxygen Therapy for Acutely Ill Medical Patients: A Clinical Practice Guideline},
shorttitle = {Oxygen Therapy for Acutely Ill Medical Patients},
author = {Siemieniuk, Reed A C and Chu, Derek K and Kim, Lisa Ha-Yeon and Güell-Rous, Maria-Rosa and Alhazzani, Waleed and Soccal, Paola M and Karanicolas, Paul J and Farhoumand, Pauline D and Siemieniuk, Jillian L K and Satia, Imran and Irusen, Elvis M and Refaat, Marwan M and Mikita, J Stephen and Smith, Maureen and Cohen, Dian N and Vandvik, Per O and Agoritsas, Thomas and Lytvyn, Lyubov and Guyatt, Gordon H},
date = {2018-10-24},
journaltitle = {BMJ},
shortjournal = {BMJ},
pages = {k4169},
issn = {0959-8138, 1756-1833},
doi = {10.1136/bmj.k4169},
url = {https://www.bmj.com/lookup/doi/10.1136/bmj.k4169},
urldate = {2022-07-18},
langid = {english},
file = {/Users/vic/Zotero/storage/FVIGDW74/Siemieniuk et al. - 2018 - Oxygen therapy for acutely ill medical patients a.pdf}
}
@article{stegemanDifferentCombinedOral2013,
title = {Different Combined Oral Contraceptives and the Risk of Venous Thrombosis: {{Systematic}} Review and Network Meta-Analysis},
shorttitle = {Different Combined Oral Contraceptives and the Risk of Venous Thrombosis},
author = {Stegeman, Bernardine H. and de Bastos, Marcos and Rosendaal, Frits R. and Vlieg, A. van Hylckama and Helmerhorst, Frans M. and Stijnen, Theo and Dekkers, Olaf M.},
options = {useprefix=true},
date = {2013-09-12},
journaltitle = {BMJ (Clinical research ed.)},
shortjournal = {BMJ},
volume = {347},
eprint = {24030561},
eprinttype = {pmid},
pages = {f5298},
publisher = {{British Medical Journal Publishing Group}},
issn = {1756-1833},
doi = {10.1136/bmj.f5298},
url = {https://www.bmj.com/content/347/bmj.f5298},
urldate = {2021-04-13},
abstract = {Objective To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. Design Systematic review and network meta-analysis. Data sources PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier, and ScienceDirect up to 22 April 2013. Review methods Observational studies that assessed the effect of combined oral contraceptives on venous thrombosis in healthy women. The primary outcome of interest was a fatal or non-fatal first event of venous thrombosis with the main focus on deep venous thrombosis or pulmonary embolism. Publications with at least 10 events in total were eligible. The network meta-analysis was performed using an extension of frequentist random effects models for mixed multiple treatment comparisons. Unadjusted relative risks with 95\% confidence intervals were reported. The requirement for crude numbers did not allow adjustment for potential confounding variables. Results 3110 publications were retrieved through a search strategy; 25 publications reporting on 26 studies were included. Incidence of venous thrombosis in non-users from two included cohorts was 1.9 and 3.7 per 10 000 woman years, in line with previously reported incidences of 1-6 per 10 000 woman years. Use of combined oral contraceptives increased the risk of venous thrombosis compared with non-use (relative risk 3.5, 95\% confidence interval 2.9 to 4.3). The relative risk of venous thrombosis for combined oral contraceptives with 30-35 µg ethinylestradiol and gestodene, desogestrel, cyproterone acetate, or drospirenone were similar and about 50-80\% higher than for combined oral contraceptives with levonorgestrel. A dose related effect of ethinylestradiol was observed for gestodene, desogestrel, and levonorgestrel, with higher doses being associated with higher thrombosis risk. Conclusion All combined oral contraceptives investigated in this analysis were associated with an increased risk of venous thrombosis. The effect size depended both on the progestogen used and the dose of ethinylestradiol.},
langid = {english},
file = {/Users/vic/Zotero/storage/VH8ASVW5/Stegeman et al. - 2013 - Different combined oral contraceptives and the ris.pdf}
}
@article{toorenvliet_laparoscopic_2010,
title = {Laparoscopic Peritoneal Lavage for Perforated Colonic Diverticulitis: {{A}} Systematic Review},
shorttitle = {Laparoscopic Peritoneal Lavage for Perforated Colonic Diverticulitis},
author = {Toorenvliet, B. R. and Swank, H. and Schoones, J. W. and Hamming, J. F. and Bemelman, W. A.},
date = {2010},
journaltitle = {Colorectal Disease},
volume = {12},
number = {9},
pages = {862--867},
issn = {1463-1318},
doi = {10.1111/j.1463-1318.2009.02052.x},
url = {http://onlinelibrary.wiley.com/doi/abs/10.1111/j.1463-1318.2009.02052.x},
urldate = {2021-02-28},
abstract = {Aim This systematic review aimed to evaluate the efficacy, morbidity and mortality of laparoscopic peritoneal lavage for patients with perforated diverticulitis. Method We searched PubMed, EMBASE, Web of Science, the Cochrane Library and CINAHL databases, Google Scholar and five major publisher websites without language restriction. All articles which reported the use of laparoscopic peritoneal lavage for patients with perforated diverticulitis were included. Results Two prospective cohort studies, nine retrospective case series and two case reports reporting 231 patients were selected for data extraction. Most (77\%) patients had purulent peritonitis (Hinchey III). Laparoscopic peritoneal lavage successfully controlled abdominal and systemic sepsis in 95.7\% of patients. Mortality was 1.7\%, morbidity 10.4\% and only four (1.7\%) of the 231 patients received a colostomy. Conclusion There have been no publications of high methodological quality on laparoscopic peritoneal lavage for patients with perforated colonic diverticulitis. The published papers do, however, show promising results, with high efficacy, low mortality, low morbidity and a minimal need for a colostomy.},
langid = {english},
keywords = {colonic,Diverticulitis,laparoscopy,peritoneal lavage,peritonitis},
note = {\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1463-1318.2009.02052.x},
file = {/Users/vic/Zotero/storage/JEJMB4IX/Toorenvliet et al. - 2010 - Laparoscopic peritoneal lavage for perforated colo.pdf}
}
@article{wagnerChronicDiseaseManagement1998,
title = {Chronic Disease Management: {{What}} Will It Take to Improve Care for Chronic Illness?},
shorttitle = {Chronic Disease Management},
author = {Wagner, E. H.},
date = {1998-09},
journaltitle = {Effective clinical practice: ECP},
shortjournal = {Eff Clin Pract},
volume = {1},
number = {1},
eprint = {10345255},
eprinttype = {pmid},
pages = {2--4},
issn = {1099-8128},
abstract = {Meeting the complex needs of patients with chronic illness or impairment is the single greatest challenge facing organized medical practice. Usual care is not doing the job; dozens of surveys and audits have revealed that sizable proportions of chronically ill patients are not receiving effective therapy, have poor disease con- trol, and are unhappy with their care (1). Results of randomized trials also show that effective disease management programs can achieve substantially better outcomes than usual care, the control intervention. These trials, along with the ideas and efforts for improvement discussed in this issue, show that we can improve care and outcomes. As the articles suggest, these improvements will not come easily. If we are to improve care for most patients with chronic illness, the evidence strongly suggests that we reshape our ambulatory care systems for this purpose. Pri- mary care practice was largely designed to provide ready access and care to patients with acute, varied problems, with an emphasis on triage and patient flow; short appointments; diagnosis and treatment of symptoms and signs; reliance on laborato- ry investigations and prescriptions; brief, didactic patient education; and patient- initiated follow-up. Patients and families struggling with chronic illness have differ- ent needs, and these needs are unlikely to be met by an acute care organization and culture. They require planned, regular interactions with their caregivers, with a focus on function and prevention of exacerbations and complications. This interac- tion includes systematic assessments, attention to treatment guidelines, and behav- iorally sophisticated support for the patient's role as self-manager. These interactions must be linked through time by clinically relevant information systems and continu- ing follow-up initiated by the medical practice.},
langid = {english},
keywords = {Case Management,Chronic Disease,Comprehensive Health Care,Disease Management,Health Care,Humans,Outcome Assessment,Patient Care Team,Personal Health Services,Quality Assurance,United States}
}
@article{waterer_management_2011,
title = {Management of {{Community-acquired Pneumonia}} in {{Adults}}},
author = {Waterer, Grant W. and Rello, Jordi and Wunderink, Richard G.},
date = {2011-01-15},
journaltitle = {American Journal of Respiratory and Critical Care Medicine},
shortjournal = {Am J Respir Crit Care Med},
volume = {183},
number = {2},
pages = {157--164},
issn = {1073-449X, 1535-4970},
doi = {10.1164/rccm.201002-0272CI},
url = {http://www.atsjournals.org/doi/abs/10.1164/rccm.201002-0272CI},
urldate = {2021-03-19},
langid = {english},
keywords = {mcr,pneumologia},
file = {/Users/vic/Zotero/storage/UZTER7QR/Waterer et al. - 2011 - Management of Community-acquired Pneumonia in Adul.pdf}
}
@article{beers2019,
doi = {10.1111/jgs.15767},
url = {https://doi.org/10.1111%2Fjgs.15767},
year = 2019,
month = {jan},
publisher = {Wiley},
volume = {67},
number = {4},
pages = {674--694},
author = {Beers Criteria Update Expert Panel, AGS},
title = {American Geriatrics Society 2019 Updated {AGS} Beers Criteria{\textregistered} for Potentially Inappropriate Medication Use in Older Adults},
journal = {J Am Geriatr Soc}
}
@article{Livingston_2020,
doi = {10.1016/s0140-6736(20)30367-6},
url = {https://doi.org/10.1016%2Fs0140-6736%2820%2930367-6},
year = 2020,
month = {aug},
publisher = {Elsevier {BV}},
volume = {396},
number = {10248},
pages = {413--446},
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