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Demultiplexing

The objective of this function is to demultiplex Illumina reads that are dual-indexed. The script can identify low quality score reads and index hopping. Script will produce R1 and R2 fastq files for each known index, unknow records, and index hopped records.

Input Parameters

  • -f1,--R1_file : Read 1 File name.
  • -f2,--R2_file : Read 2 File name.
  • -f3,--R3_file : Read 3 File name.
  • -f4,--R4_file : Read 4 File name.
  • -i, --index_file : Index file name.
  • -iq,--index_cutoff : Minimum average index quality score cut off

Required parameter to run Demultiplexing_Checking_Sequence_Quality_Score_longer_runtime.py

  • -sq,--seq_cutoff : Minimum average sequence quality score cut off

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Demultiplexing Python3 Script for Illumina Data

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  • Python 95.4%
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