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pierrepo committed Mar 23, 2023
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[![SWH](https://archive.softwareheritage.org/badge/origin/https://github.com/data-fun/3d-genome-builder/)](https://archive.softwareheritage.org/browse/origin/?origin_url=https://github.com/data-fun/3d-genome-builder)

<img align="right" width="200px"
src="assets/Neurospora_crassa_WT_50kb.gif"
alt="3D structure of the Neurospora crassa genome at 50 kb resolution">
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3D genome builder (3DGB) is a workflow to build 3D models of genomes from HiC raw data and to integrate omics data on the produced models for further visual exploration.
3DGB bundles [HiC-Pro](https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0831-x), [PASTIS](https://academic.oup.com/bioinformatics/article/30/12/i26/385087) and custom Python scripts into a unified Snakemake workflow with limited inputs (see *Preparing Required Files*). 3DGB produces annotated 3D models of genome in PDB and G3D formats.

[![SWH](https://archive.softwareheritage.org/badge/origin/https://github.com/data-fun/3d-genome-builder/)](https://archive.softwareheritage.org/browse/origin/?origin_url=https://github.com/data-fun/3d-genome-builder)
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