PLeXuS - Protein Learning EXUberant Software. This is an app collecting simple games helping you to learn protein-protein interactions easier. It is heavily built upon Igraph package and has a visual interface made in Tkinter.
Learn protein interactions in delineated signaling cascades from (KEGG, SIGNOR, Panther or Reactome) or load your own gene sets and and highlight connections between them as stored in the comprehensive graph collected by Omipath. Target and background gene sets can be filtered based on the number of pubmed references,centrality measures of the gene nodes or user specific score calculated based on the number of previously incorrect guesses.
Currently available modes
Labirinth game Pave the path through a mesh of proteins selecting only edges supported by the biological data; help yourself using snippets of functional gene annotations from Uniprot or Ensemble masked on different levels. Store your corrent and incorrect guesses, building personal statstics.
Mines game Organized in the similar way as Labirinth game, but the objective is reversed - highlight only genes which do not have protein interaction with a given gene.