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Using Tissue-Derived Data (Tumor/Germline via Buffy Coat WES Data and Normal/Tumor Genotyping Array Data)? #139

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Danielsm8 opened this issue Oct 9, 2024 · 0 comments

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@Danielsm8
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Hello,
I'm working on a plasma cfDNA project that has paired tumor WES data and normal/tumor genotyping array data (Infinium GSA Panel). With the paired WES data that have both normal and tumor data, I can get ichorCNA to run perfectly, however, I do not have normal tissue WES data for many samples.

  1. I was wondering if germline data derived from buffy coat samples can be used with ichorCNA?
  2. I was also wondering if Infinium GSA panel data derived from both normal and tumor tissue can be used with ichorCNA?

Thank You!

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