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Change Log

All notable changes to this project will be documented in this file.

The format is based on Keep a Changelog and this project adheres to Semantic Versioning.

[0.4.0] - 2025-01-30

Added

  • CONTRIBUTING.md file as per #24
  • An initial suite of automated tests compatible with pytest and coverage. Issue #23

Fixed

  • Error in the dose_absorbed macro which was causing an extra ka parameter to be added to the model.

[0.3.3] - 2024-07-21

Fixed

  • Fix for Issue #20

[0.3.2] - 2024-07-18

Fixed

  • Problem with local variable F not being defined when f is a Parameter instance.; Fix for Issue #17

[0.3.1] - 2024-07-03

Fixed

  • Missing sub-packages problem when installing with pip from the repo; Fix for Issue #16

[0.3.0] - 2024-07-01

Added

  • New PD macro fixed_effect encoding a fixed-effect model for the effect/response. Issue #7
  • intercept argument for the linear_effect PD model which allows users to set the y-intercept of the linear model. Issue #9
  • New PD macro loglinear_effect encoding a log-linear model for the effect/response as a function of concentration. Issue #8
  • New util module that defines the simulate function: Issue #11

Changed

  • Replaced the setup.py script with a pyproject.toml; Issue #13
  • linear_effect PD macro: updated the parameter names to prefix them with LinEffect_ to make sure they are unique.

[0.2.1] - 2023-10-17

Fixed

  • Updated the mechanism for the dose_absorbed dosing macro function to use a precursor; Fix for Issue #4

[0.2.0] - 2023-05-23

Added

  • dose_absorbed dosing macro function to the pysb.pkpd.macros module.
  • linear_effect PD macro function to the pysb.pkpd.macros module.
  • one_compartment compartment macro function to the pysb.pkpd.macros module.
  • drug_monomer macro function to the pysb.pkpd.macros module.
  • Functions from the macros module are imported into pkpd.__init__ so that they can be called directly from the pkpd namespace.
  • example-notebooks directory with a new PKRO example case.

[0.1.0] - 2023-05-23

Added

  • Initial development version of the package.

[Unreleased] - yyyy-mm-dd

N/A

Added

Changed

Fixed