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update readme
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Zilong-Li committed Feb 18, 2025
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Expand Up @@ -92,7 +92,7 @@ See [[file:CHANGELOG.org][change log]] here.

- If using the PCAngsd algorithm, please also cite [[https://www.genetics.org/content/210/2/719][Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data]].

- If using the ancestry ajusted LD statistics for pruning and clumping, please also cite [[https://doi.org/10.1101/2024.05.02.592187][Measuring linkage disequilibrium and improvement of pruning and clumping in structured populations]].
- If using the ancestry ajusted LD statistics for pruning and clumping, please also cite [[ https://doi.org/10.1093/genetics/iyaf009][Measuring linkage disequilibrium and improvement of pruning and clumping in structured populations]].

* Quick start

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of samples (=N=) and the number of variants / features (=M=) and the top PCs
(=k=). Here is an overview and the recommendation.

|--------------------------+-----------+-------------------------------------------|
| Method | Accuracy | Scenario |
|--------------------------+-----------+-------------------------------------------|
| IRAM (-d 0) | Very high | large scale data with =N < 5000= |
| Window-based RSVD (-d 2) | Very high | large scale data with =M > 1,000,000= |
| RSVD (-d 1) | High | accuracy insensitive, any scale data |
| Full SVD (-d 3) | Exact | cost insensitive, full variance explained |
|--------------------------+-----------+-------------------------------------------|
|--------------------------+-------------------------+-----------+-----------------------------------------|
| Method | Scenario | Accuracy | Speed |
|--------------------------+-------------------------+-----------+-----------------------------------------|
| Full SVD (-d 3) | full variance explained | Exact | slow for big =N= or =M= |
| Window-based RSVD (-d 2) | data with =M >> N= | Very high | fast (only 7 iterations used) |
| IRAM (-d 0) | data with =N < 5000= | Very high | denpends on =N= and # iterations |
| RSVD (-d 1) | accuracy insensitive | High | depends on # iterations for convergence |
|--------------------------+-------------------------+-----------+-----------------------------------------|

** Input formats

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