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updated vignette
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ToledoEM authored Oct 2, 2024
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8 changes: 5 additions & 3 deletions vignettes/msigdf.Rmd
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Expand Up @@ -10,7 +10,9 @@ author:
maintenace: Enrique M. Toledo (enriquetoledo@gmail.com)
package: msigdf
output:
BiocStyle::html_document
BiocStyle::html_document:
theme: united
highlight: zenburn
abstract: |
This data package contains the Molecular Signature Database (MSigDB) for both human and predicted mouse orthologs in separate data frames (tibbles).
Each data frame (`msigdf.human` and `msigdf.mouse`) contain three columns: the collection (Hallmark, or c1-c8), the gene set, and Entrez IDs
Expand Down Expand Up @@ -38,7 +40,7 @@ _The gene sets contained in the MSigDB are from a wide variety of sources, and r
**_Prodecure:_**

_1. The current MSigDB v2023.2 gmt files were downloaded from Broad ftp._
_2. This was domne with the human and mouse gene sets_
_2. This was done with the human and mouse gene sets_
_3. Each collection was converted to a list in R, and written to a RData file using `save()`._

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Expand All @@ -49,7 +51,7 @@ See the script in `data-raw/` to see how the data frames (tibbles) were created.

There are three data frames (tibbles) this package. The `msigdf.human` data frame has columns for each MSigDB collection divided by sub-collection (like cc, bp and mf for C5). The format of the data is tidy, so each row is a single gene set collection, sub-collection and gene symbol. The `msigdf.mouse` data frame has the same structure for mouse orthologs. The `msigdf.urls` data frame links the name of the gene set to the URL on the Broad's website.

New C5 ontology information into was added into category subcode for easy filtering and consistency
New C5 ontology information was added to the category subcode for easy filtering and consistency.

- HPO: Human Phenotype Ontology
- MF: GO Molecular Function ontology
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313 changes: 191 additions & 122 deletions vignettes/msigdf.html

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