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CloseCall: pipeline for processing RNA-RNA proximity data

CloseCall is a bioinformatics pipeline for identifying RNA-RNA interactions in NGS datasets generated using a new high-throughput protocol named Proximity RNA-seq to fix and sequence RNA complexes. The CloseCall pipeline has 3 main components:

  1. Mapping and QC
  2. Monte Carlo Simulation to identify statistically significant RNA-RNA interactions

The software is written in Perl and Java.

Documentation

The CloseCall documentation can be found with the code in the docs subfolder and can also read online.

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Credits

CloseCall was written by Steven Wingett, part of the Babraham Bioinformatics group.

License

GNU General Public License v3.0

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Pipeline for processing Proximity RNA-seq datasets

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