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Optimize alignment view 'decoration' #232

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nataled opened this issue Apr 9, 2021 · 4 comments
Open

Optimize alignment view 'decoration' #232

nataled opened this issue Apr 9, 2021 · 4 comments
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CanDelay Issues that can be delayed Web Site Report issue with PRO website (proconsortium.org)

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@nataled
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nataled commented Apr 9, 2021

Page loading for terms with a lot of sequences to align is very slow. https://proconsortium.org/app/entry/PR%3A000036285/ is a good example. All the sequence variants use the same reference sequence, so no alignment is necessary. It must be the decoration that is slow. This needs to be optimized.

@nataled nataled added the Web Site Report issue with PRO website (proconsortium.org) label Apr 9, 2021
@nataled
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nataled commented Apr 9, 2021

From Julie:
I can confirm that when loading the very slow msa for https://proconsortium.org/app_test/entry/PR:000036285/ that has 230 rows there is only one sequence for P49768 so muscle doesn't actually run. It does take some time for the server to respond with the annotated data it returns (which includes all the details of the ptms and sequences) so it is probably worth optimizing that code too in addition to the angularjs code that the browser runs over that data that actually generates the html.

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nataled commented Apr 9, 2021

This page times out: https://proconsortium.org/app_test/entry/PR:P20039

Unclear if that's related to decoration since there is no UniProtKB accession indicated on the definition line.

@Julie-Cowart
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Julie-Cowart commented Apr 9, 2021 via email

@nataled
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nataled commented Jun 4, 2021

All the decoration is done within the client browser--this is slow. The database retrieval is also slow. Will need to look into how these each can be optimized.

@nataled nataled added CanDelay Issues that can be delayed and removed Discuss labels Jun 4, 2021
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