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AtacWorks Release 0.1.0

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@tijyojwad tijyojwad released this 27 Nov 04:00
· 439 commits to master since this release
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This is the first official release of AtacWorks. AtacWorks is a deep learning-based toolkit for denoising and peak calling from noisy ATAC-Seq data. While currently tested only on ATAC-Seq, AtacWorks can also be applied to other epigenomic data types such as ChIP-Seq or DNase-Seq. A detailed description and results for several use cases are given in the preprint: https://www.biorxiv.org/content/10.1101/829481

The main components of this release are:

  1. Data reading and writing from BED, BEDGRAPH and BigWig formats
  2. Training deep learning models using a customizable resnet architecture
  3. Pre-trained models that can be applied to new data
  4. Inference using a newly trained or provided model, producing a denoised ATAC-Seq signal and peak calls
  5. Evaluating model performance on denoising and peak calling tasks.