-
Notifications
You must be signed in to change notification settings - Fork 1
Olfactory Mitral Cell: I-A and I-K currents (Wang et al 1996)
ModelDBRepository/3648
Folders and files
Name | Name | Last commit message | Last commit date | |
---|---|---|---|---|
Repository files navigation
NEURON mod files for the I-A and I-K currents from the paper: Wang, et al., Whole-cell K+ currents in identified olfactory bulb output neurones of rats. J Physiol. 1996 490:63-77. Running the kinetics.hoc simulation file will show the activation and inactivation steady-states, the time constants, and a family of curves generated modeling the same protocols used for Figs.6B-C of the paper. Markers show the experimental values reported in the paper (Table.1). For the I-A current, two parameters (shi_kamt and sha_kamt) have been introduced to take into account the shift in the kinetics (Fig.4B) observed using different bathing solutions (with or without Ca++, see legend of Fig.4). Default values for shi_kamt (inactivation) and sha_kamt (activation) are 5.7 and 9.9mV, respectively. shi_kamt = sha_kamt = 0 was used here (solid lines in Fig.4B). Under unix systems: to compile the mod files use the command nrnivmodl and run the simulation hoc file with the command nrngui kinetics.hoc Under Windows using NEURON 5.1: to compile the mod files use the "mknrndll" command. A double click on the simulation file kinetics.hoc will open the simulation window. Questions on the model parameters should be directed to the authors. Questions on how to use this model with NEURON should be directed to michele.migliore@pa.ibf.cnr.it
About
Olfactory Mitral Cell: I-A and I-K currents (Wang et al 1996)
Topics
Resources
Stars
Watchers
Forks
Releases
No releases published
Packages 0
No packages published