Scn2a Compartmental Model

Models and Jupyter notebooks for:

** Paper reference **

The simulations were tested with:

• Python v3.8.5

• NEURON v8.0

Model in ./Na12 Analysis/NaV12_analysis.ipynb corresponds to Figure 3, S3A-B, S4.

Model in ./Ri Increase/25% Ri Increase Figures.ipynb corresponds to Figure S3C.

Compile in mechanisms folder by running shell command nrnivmodl (Mac)/mknrndll (Windows) and copy x86_64 folder (Mac)/nrnmech.dll (Windows) to model folder.

For additional information, please contact bens.roy@gmail.com or henry.kyoung@ucsf.edu

Changelog

2023-02-28: updated for C++ compatibility (NEURON 9+) 2023-04-20: updated for SoA data compatibility (NEURON 9+)