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Voltage imaging calibration in tuft dendrites of mitral cells (Djurisic et al 2004)
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<html> This is the readme for simulation code associated with the paper<p/> Djurisic M, Antic S, Chen WR, Zecevic D (2004) Voltage imaging from dendrites of mitral cells: EPSP attenuation and spike trigger zones. J Neurosci 24:6703-14 <br/> <a href="http://dx.doi.org/10.1523/JNEUROSCI.0307-04.2004">http://dx.doi.org/10.1523/JNEUROSCI.0307-04.2004</a><p/> This model was contributed by Dejan Zecevic.<p/> This model requires NEURON which is freely available from <a href="http://neuron.yale.edu">http://neuron.yale.edu</a><p/> Usage:<p/> To run the model (linux/unix) compile the mod file with a command like<p/> nrnivmodl<p/> or for mswin or mac use makenrndll. Start with the mosinit.hoc file (linux):<p/> nrngui mosinit.hoc<p/> or by double clicking (mswin) or dragging and dropping (mac). If you need more help to run the simulation on your platform please consult this page:<p/> <a href="https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide.cshtml">https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide.cshtml<a/> <p/> After running the model you should see the propagation of a passive EPSP into the tuft compartments similar to Fig 3G trace 3 in the paper:<p/> <img src="./screenshot1.png" alt="screenshot1" width="650"> <p/> This model entry includes a mitral cell morphology with a detailed reconstruction of a tuft (slightly more elaborate than the one depicted in Fig 3G in the paper) depicted below in a shape plot with show diameter shape style selected<p/> <img src="./screenshot2.png" alt="screenshot2" width="650"> </html>
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Voltage imaging calibration in tuft dendrites of mitral cells (Djurisic et al 2004)
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