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cell.p
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//genesis
//
// cell.p - template neuron prototype
//
// Reduction of the original model by Huss M, Lansner A, Wallen P,
// El Manira A, Grillner S, Kotaleski JH. Roles of ionic currents
// in lamprey CPG neurons: a modeling study. J Neurophysiol. 2007
// Apr;97(4):2696-711. Epub 2007 Feb 7 (ModelDB accession number 93319).
//
// The cell morphology is simplified in that the small adjacent membrane
// compartments are lumped together to make longer cylinders. Cell membrane
// of the simplified model contains 16 compartments: soma, axon initial
// segment, 2 primary, 4 secondary and 8 tertiary dendrites.
*relative
*cartesian
*asymmetric
*set_compt_param EREST_ACT -0.078
*set_compt_param ELEAK -0.078
*set_global RA 1
*set_global RM 1
*set_global CM 0.01
*start_cell /library/soma
soma none 0 0 20 20 Na 320 Ks 40 Kt 50 CaN 80 CaN_pool -1.25e5 KCaN 60 CaL 4 Na_pool -5e11 Na_slow_pool -3e9 KNa 50 KNa_slow 5.2 Glyc -1e-9 AMPA -0.25e-9 NMDA -0.12e-9
*makeproto /library/soma
*start_cell /library/iseg
iseg none 0 0 50 5 shNa 20000 Kt 6000
*makeproto /library/iseg
*start_cell /library/prim_dend
prim_dend none 90 0 0 5 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 Glyc -1e-9 AMPA -0.25e-9 NMDA -0.12e-9
*makeproto /library/prim_dend
*start_cell /library/secn_dend
secn_dend none 150 0 0 3 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 AMPA -0.25e-9 NMDA -0.12e-9
*makeproto /library/secn_dend
*start_cell /library/tert_dend
tert_dend none 240 0 0 2 Na 320 Ks 40 Kt 20 CaN 80 CaN_pool -1.25e5 KCaN 600 CaL 2 CaLVA 575 Na_pool -5e11 Na_slow_pool -3e9 KNa 150 KNa_slow 52 AMPA -0.25e-9 NMDA -0.12e-9
*makeproto /library/tert_dend
*start_cell
*compt /library/soma
soma none 0 0 20 20
*compt /library/iseg
iseg soma 0 0 50 5
*compt /library/prim_dend
prox1 soma 90 0 0 5
prox2 soma 90 0 0 5
*compt /library/secn_dend
medi1 prox1 150 0 0 3
medi2 prox1 150 0 0 3
medi3 prox2 150 0 0 3
medi4 prox2 150 0 0 3
*compt /library/tert_dend
dist1 medi1 240 0 0 2
dist2 medi1 240 0 0 2
dist3 medi2 240 0 0 2
dist4 medi2 240 0 0 2
dist5 medi3 240 0 0 2
dist6 medi3 240 0 0 2
dist7 medi4 240 0 0 2
dist8 medi4 240 0 0 2