Cant find chain

[aspitaleri]

Hi there,
thanks for the script! I am using to generate pdb with missense mutations. It works except for this:

pymissense O95477 abaca1 --maxacid 2224 --pdbpath 7tc0.pdb --tsv /tmp/alpha.tsv

Cant find chain for O95477 in 7tc0.pdb
The pdb is from rcsb. Using --pdbpath 7TC0 it works. The chain is present and I tried also to keep only ATOM lines.

BTW, is it possible to get the tsv or the matrix used to generate the heatmap plot? To post process the data.

Best

[thorstenwagner]

Thanks for reporting this! I'm not in the office, but I will look into it when I'm back next week.

[thorstenwagner]

Quick comment: I downloaded the pdb from rcsb and I cant find uniprot id O95477 ?

[aspitaleri]

https://www.uniprot.org/uniprotkb/O95477/entry
Using the --pdbpath 7TC0 it works. There is somethig weird in the rcsb file when downloaded first.