The FRIEND software was developed at Cognitive and Behavioral Neuroscience Unit and Neuroinformatics Workgroup, D'Or Institute for Research and Education (IDOR, http://www.idor.org)– R. Diniz Cordeiro, 30, 22281-100, Rio de Janeiro, Brazil, Rio de Janeiro, Brazil. The software is registered at the Brazilian agency of patents and trademarks, Instituto Nacional da Propriedade Industrial (INPI – http://www.inpi.gov.br), under request number 137820. FRIEND's license is open source and free for non-commercial use. It was based on the FSL license and thus follows similar permissions and restrictions.