Skip to content

Commit

Permalink
fix greenlead
Browse files Browse the repository at this point in the history
  • Loading branch information
rcorces committed May 19, 2020
1 parent 309f0a3 commit 48b05ba
Showing 1 changed file with 1 addition and 1 deletion.
2 changes: 1 addition & 1 deletion bookdown/13_Deviations.Rmd
Original file line number Diff line number Diff line change
Expand Up @@ -48,7 +48,7 @@ set.seed(1)

# ChromVAR Deviatons Enrichment with ArchR

As shown in previous chapters, TF motif enrichments can help us predict which regulatory factors are most active in our cell type of interest. These enrichments, however, are not calculated on a per-cell basis and they do not take into account the insertion sequence bias of the Tn5 transposase. [chromVAR](https://greenleaflab.github.io/chromVAR/index.html), an R packaged from the Greenlead Lab, was created to account for these issues. chromVAR is designed for predicting enrichment of TF activity on a per-cell basis from sparse chromatin accessibility data. The two primary outputs of chromVAR are:
As shown in previous chapters, TF motif enrichments can help us predict which regulatory factors are most active in our cell type of interest. These enrichments, however, are not calculated on a per-cell basis and they do not take into account the insertion sequence bias of the Tn5 transposase. [chromVAR](https://greenleaflab.github.io/chromVAR/index.html), an R packaged from the Greenleaf Lab, was created to account for these issues. chromVAR is designed for predicting enrichment of TF activity on a per-cell basis from sparse chromatin accessibility data. The two primary outputs of chromVAR are:

```{r include=FALSE, eval=FALSE,echo=FALSE}
# JJJ I would prefer to have more clear descriptions about deviations vs z scores for chromVAR. I've always found this very nuanced and it was never clear which metric should be used in which scenarios.
Expand Down

0 comments on commit 48b05ba

Please sign in to comment.