Adopting gene score model to bulk ATAC-seq data

[ammaralsheik]

The gene score model that was optimized in ArchR performs really well and, such an approach is lacking for bulk ATAC-seq analysis, how possible is it to adapt this model to be used with bulk datasets?

[rcorces]

We do not have code for this at the moment but it is something that I've been asked for multiple times recently. In theory, this should work very well - it just doesnt fit in the current ArchR ecosystem because we have no support for bulk data.

[ammaralsheik]

Thank you, Ryan, Yes i definitely understand that it's not a direct fit. Hopefully someone will be able to adopt it or if we do we can share the code in the future.