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For any information regarding this project, please contact antoine.meilliez@hec.edu

Molecule classification

This project aims to detect automatically molecule and transcriptions site involved in the first step of developpement of drosophilia embryo. Such information can be extracted from microscop images such as this one:

microscop image

This package implements several tools requested to achieve this classification:

  • Image filtering and scaling
  • Region extraction
  • Blob detection
  • Contours detection
  • 3D region aggregation
  • Region features extraction
  • Unsupervised classification benchmarker
  • File manager and viewer
  • Performance monitoring

A standard pipeline has been implemented in demo.py pipeline image

Exemples

Region detection

Region detection performed on cells. region image

Cell contour detection

This detection is used as feature of classification algorithm. Region are tagged regarding the cell they are embedded in or not. Cell contours

Various data exploration prior to classification

Region intensity exploration along the z axis z_distribution

Intensity / area ratio ratio_mean_area

Distribution filtering. This part enables classification of Transcription site distribution_filtering

Features distribution analysis features_distribution

Unsupervised classification benchmark

A benchmark tool has been implemented to identify which classification algorithm presents the best results. The following classification was handled on the raw features (prior to distribution filtering) benchmark

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