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Setting up CaConc #254

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analkumar2 opened this issue Apr 24, 2019 · 2 comments
Open

Setting up CaConc #254

analkumar2 opened this issue Apr 24, 2019 · 2 comments

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@analkumar2
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analkumar2 commented Apr 24, 2019

Moose requires the thickness, diameter, and length of the calcium shell instead of the drive value B. The ModleDB files give the value of the drive value B directly, and sometimes the value is higher than which can be attainable the shell thickness, diameter, and length.

Thickness = D-sqrt(D^2 - 2/(piLB*F)) where D = shell diameter which has the maximum value of the compartment's diameter; B = current drive; L = shell length which has the maximum value of the compartment's length; F = Faraday constant

For example, for compartment length = 100e-6m, compartment diameter = 100e-6, B has to be at least 6598098 SI units. In Combe et, al,. they have used B = 575792.7 https://senselab.med.yale.edu/ModelDB/showmodel.cshtml?model=244416&file=/CombeEtAl2018/cad.mod#tabs-2 which cannot be set up.

One workaround that I have been using is to change the B value after building the model using
moose.element('/model/elec/soma/Ca_conc').B = 575792.7

@dilawar
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dilawar commented May 22, 2019

Any resolution?

@analkumar2
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Only the workaround.

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