FGWAS2

Version of code used for Guan et al., Family-based genome-wide association study designs for increased power and robustness.

Two generation PGS analysis accounting for assortative mating

Release implemented two-generation polygenic score analysis accounting for assortative mating. This implements the method described in: Estimation of indirect genetic effects and heritability under assortative mating, Alexander Young, BioRxiv 2023.

Simulation

New simulation module with exercise and improved polygenic score analysis script.

Young et al 2022

Release accompanying forthcoming publication: Young et al., Mendelian imputation of parental genotypes improves estimates of direct genetic effects, Nature Genetics (2022).

EA4

Version of code used for assortative mating and family based polygenic score analyses in Okbay et al. 2022.