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======================================================== author: ALeksandra Dąbrowska, Alicja Gosiewska date: width: 1400 height: 900 css: custom.css

Grupa MI^2 i MI^2 DataLab

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Podstawowe pojęcia

  • Gen
  • Sonda CpG
  • Ekspresja genu
  • Metylacja DNA plot of chunk unnamed-chunk-7

Ekspresja

                             SUBTYPE AANAT AARSD1 AATF AATK
TCGA-A1-A0SB-01A-11R-A144-07  Normal     9   2354 2870  317
TCGA-A1-A0SD-01A-11R-A115-07    LumA     2   1846 5656  312
TCGA-A1-A0SE-01A-11R-A084-07    LumA    11   3391 9522  736
TCGA-A1-A0SF-01A-11R-A144-07    LumA     0   2169 4625  169
TCGA-A1-A0SG-01A-11R-A144-07    LumA     1   2273 3473   92

     id log2.fold         pval mean_LumA mean_other     mean
1 AURKB  2.339920 3.191000e-32  539.0426  2323.8868  1485.01
2  CBX2  2.895062 2.834335e-26  632.5106  4296.6038  2574.48
3 KPNA2  1.447288 8.551812e-24  11547.36   26427.38 19433.77
4 PRR11  3.822148 2.286874e-22   396.383   3479.981  2030.69
5 BIRC5  1.988998 1.953941e-21  1957.085   6658.358  4448.76
6  GSG2  1.405039 3.527773e-21  278.2128   629.3396   464.31